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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2016, Volume 67, Issue 4,



Bogdan Tita, Gheorghe Furau, Eleonora Marian, Dumitru Tita, Cristian Furau

Anti-inflammatory Drugs Interacting with Cu(II) Metal Ion Synthesis, characterization and thermal behaviour of the complex with ketoprofen

Abstract:

New metal (II) complex with empirical formula [Cu(KET)2]2.0.5H2O (where KET = C6H5COC6H4CH(CH3)COO-) was isolated and investigated. The elemental analysis, Fourier transformed infrared spectroscopy (FT-IR), X-ray diffraction powder (XRPD) and thermal analysis were used to study solid Ketoprofen (KET) of Cu(II) metal ion. The thermal behavior was studied by thermogravimetry (TG), derivative thermogravimetry (DTG) and differential scaning calorimetry (DSC) methods under non-isothermal conditions in a dynamic air atmosphere. The results provided informations of the composition, structure, thermal behavior and thermal decomposition. The FT-IR spectra of studied complex revealed also absorption of the carboxylate group, for which is important the position of asymmetric, symmetric frequencies. The value of their separation allow to deduce about type of coordination these groups.
Keywords:
anti-inflammatory drug; ketoprofen; FT-IR spectroscopy; X-ray analysis; thermal analysis

Issue: 2016, Volume 67, Issue 4
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