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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

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Revista de Chimie (Rev. Chim.), Year 2016, Volume 67, Issue 9,





FRANCISC FLORIN BARTOK, NORINA CONSUELA FORNA
Bone Loss Biomarkers Evaluation as an Early Diagnosis and Prognostic Factor of Peri-implantitis

Abstract:

Peri-implantitis presents inflammatory process that affects soft and hard supporting tissues of osseointegrated implant. Inflammatory processes that occur in the case of periodontitis and in the case of peri-implantitis have similar characteristics, with bone loss as defining element. The studies have shown that peri-implant and gingival sulcus have a similar structure, sharing the same immune components in the inflammatory process. At molecular level, the balance between bone-resorbing osteoclasts and bone-producing osteoblasts is mediated by RANK (receptor activator of nuclear factor kappa B). The current scientific data doesn’t offer specific information regarding the role of RANK in the process of bone resorption in peri-impantitis/periodontitis. The aim of this study was to investigate if there are any correlations between receptor activator of nuclear factor kappa B (RANK) concentrations in peri-implant crevicular fluid and clinical parameters that reflect inflammatory nature of peri-implantitis. Keywords: RANK, peri-implantitis, dental implant, periodontitis

Issue: 2016, Volume 67, Issue 9
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