The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks

Alexa, Anisia Iuliana; Cantemir, Alina; Antioch, Iulia; Balmus, Ioana Miruna; Cojocaru, Sabina; Gardikiotis, Rodica; Luca, Andrei; Filip, Mihai-Andrei; Ababei, Daniela Carmen; Zamfir, Carmen Lacramioara

Anisia Iuliana Alexa, Alina Cantemir, Iulia Antioch, Ioana Miruna Balmus, Sabina Cojocaru, Rodica Gardikiotis, Andrei Luca, Mihai-Andrei Filip, Daniela Carmen Ababei, Carmen Lacramioara Zamfir

The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks

Abstract:

Oxidative damage is a biochemical event currently incriminated in the occurrence of many disorders. The range of affections varies, from psychiatric illnesses, like depression, schizophrenia, Alzheimer‘s disease, for instance, to somatic disorders such as carcinogenesis or diabetes. Moreover, ophthalmological pathology is also affected in their development by the oxidative stress factor. In the present study, we focused on following the changes which occur in the serum of rats exposed to environmental stress conditions (swimming and treadmill exercises) by determinations of superoxide dismutase (SOD), glutathione peroxidase (GPX) specific activity and malondialdehyde (MDA) concentration. There are important biomarkers of oxidative stress, suspected to play a relevant role in the pathology of dry eye syndrome. Our preliminary oxidative stress analysis of the serum, sampled from animals exposed to physical stress in attempt to induce dry eye syndrome pathology, showed that the levels of SOD and GPX enzymes were higher as compared to controls. Also, MDA concentration was decreased with a significant value attributed to the swimmer rats compared to controls.

Keywords:
superoxide dismutase; glutathione peroxidase; malondialdehyde; catalase; rat animal models; oxidative stress; environmental stress

Issue: 2017, Volume 68, Issue 2

Pages: 350-353

Publication date: 2017/3/15

https://doi.org/10.37358/RC.17.2.5451

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ALEXA, A.I., CANTEMIR, A., ANTIOCH, I., BALMUS, I.M., COJOCARU, S., GARDIKIOTIS, R., LUCA, A., FILIP, M., ABABEI, D.C., ZAMFIR, C.L., The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks, Rev. Chim., 68(2), 2017, 350-353.

Vancouver
Alexa AI, Cantemir A, Antioch I, Balmus IM, Cojocaru S, Gardikiotis R, Luca A, Filip M, Ababei DC, Zamfir CL. The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks. Rev. Chim.[internet]. 2017 Feb;68(2):350-353. Available from: https://doi.org/10.37358/RC.17.2.5451

APA 6th edition
Alexa, A.I., Cantemir, A., Antioch, I., Balmus, I.M., Cojocaru, S., Gardikiotis, R.,... Zamfir, C.L. (2017). The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks. Revista de Chimie, 68(2), 350-353. https://doi.org/10.37358/RC.17.2.5451

Harvard
Alexa, A.I., Cantemir, A., Antioch, I., Balmus, I.M., Cojocaru, S., Gardikiotis, R., Luca, A., Filip, M., Ababei, D.C., Zamfir, C.L. (2017). 'The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks', Revista de Chimie, 68(2), pp. 350-353. https://doi.org/10.37358/RC.17.2.5451

IEEE
A.I. Alexa, A. Cantemir, I. Antioch, I.M. Balmus, S. Cojocaru, R. Gardikiotis, A. Luca, M. Filip, D.C. Ababei, C.L. Zamfir, "The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks". Revista de Chimie, vol. 68, no. 2, pp. 350-353, 2017. [online]. https://doi.org/10.37358/RC.17.2.5451

Text
Anisia Iuliana Alexa, Alina Cantemir, Iulia Antioch, Ioana Miruna Balmus, Sabina Cojocaru, Rodica Gardikiotis, Andrei Luca, Mihai-Andrei Filip, Daniela Carmen Ababei, Carmen Lacramioara Zamfir,
The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks,
Revista de Chimie,
Volume 68, Issue 2,
2017,
Pages 350-353,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.2.5451.
(https://revistadechimie.ro/Articles.asp?ID=5451)
Keywords: superoxide dismutase; glutathione peroxidase; malondialdehyde; catalase; rat animal models; oxidative stress; environmental stress

RIS
TY - JOUR
T1 - The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks
A1 - Alexa, Anisia Iuliana
A2 - Cantemir, Alina
A3 - Antioch, Iulia
A4 - Balmus, Ioana Miruna
A5 - Cojocaru, Sabina
A6 - Gardikiotis, Rodica
A7 - Luca, Andrei
A8 - Filip, Mihai-Andrei
A9 - Ababei, Daniela Carmen
A10 - Zamfir, Carmen Lacramioara
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 2
SP - 350
EP - 353
UR - https://doi.org/10.37358/RC.17.2.5451
KW - superoxide dismutase
KW - glutathione peroxidase
KW - malondialdehyde
KW - catalase
KW - rat animal models
KW - oxidative stress
KW - environmental stress
ER -

BibTex
@article{RevCh2017P350,
author = {Alexa Anisia Iuliana and Cantemir Alina and Antioch Iulia and Balmus Ioana Miruna and Cojocaru Sabina and Gardikiotis Rodica and Luca Andrei and Filip Mihai-Andrei and Ababei Daniela Carmen and Zamfir Carmen Lacramioara},
title = {The Dynamics of the Main Oxidative Stress Chemical Markers in the Serum of Rats Stressed by Various Behavioural Tasks},
journal = {Revista de Chimie},
volume = {68},
number = {2},
pages = {350-353},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.2.5451},
url = {https://revistadechimie.ro/Articles.asp?ID=5451}
}

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