Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation

Stanescu, Iulia Ioana; Totan, Alexandra; Rus, Florentina; Miricescu, Daniela; Mocanu, Brandusa; Calenic, Bogdan; Greabu, Maria

Iulia Ioana Stanescu, Alexandra Totan, Florentina Rus, Daniela Miricescu, Brandusa Mocanu, Bogdan Calenic, Maria Greabu

Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation

Abstract:

The past decades demonstrated that saliva and its components represent a remarkable diagnosis fluid with valuable clinical uses for both oral and systemic diseases. At the same time it is well established that oxidative stress is involved in a wide number of pathologies, including periodontitis. The specific aim of the present study which included 50 subjects is to determine if saliva can be used in clinical settings to correlate oxidative stress and tissue destruction markers with the severity of periodontal disease. An important oxidative stress marker - 8-hydroxydesoxyguanosine (8-OHdG) and a collagen degradation marker - beta-crosslaps (b-CTX) were quantified in both saliva and gingival crevicular fluid (GCF) using ELISA kits and were found to be significantly increased in the chronic periodontitis group when compared to respective controls (p[0.05). At the same time positive correlations were observed between whole saliva and gingival crevicular fluid (p[0.05). Significant correlations were also determined between GCF and salivary markers and clinical parameters of periodontal disease. Present results demonstrate that saliva and its components can successfully be used in clinical settings and represents a reliable tool for assessing periodontal disease severity.

Keywords:
saliva; periodontal disease; gingival crevicular fluid

Issue: 2017, Volume 68, Issue 6

Pages: 1201-1204

Publication date: 2017/7/15

https://doi.org/10.37358/RC.17.6.5641

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
STANESCU, I.I., TOTAN, A., RUS, F., MIRICESCU, D., MOCANU, B., CALENIC, B., GREABU, M., Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation, Rev. Chim., 68(6), 2017, 1201-1204.

Vancouver
Stanescu II, Totan A, Rus F, Miricescu D, Mocanu B, Calenic B, Greabu M. Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation. Rev. Chim.[internet]. 2017 Jun;68(6):1201-1204. Available from: https://doi.org/10.37358/RC.17.6.5641

APA 6th edition
Stanescu, I.I., Totan, A., Rus, F., Miricescu, D., Mocanu, B., Calenic, B. & Greabu, M. (2017). Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation. Revista de Chimie, 68(6), 1201-1204. https://doi.org/10.37358/RC.17.6.5641

Harvard
Stanescu, I.I., Totan, A., Rus, F., Miricescu, D., Mocanu, B., Calenic, B., Greabu, M. (2017). 'Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation', Revista de Chimie, 68(6), pp. 1201-1204. https://doi.org/10.37358/RC.17.6.5641

IEEE
I.I. Stanescu, A. Totan, F. Rus, D. Miricescu, B. Mocanu, B. Calenic, M. Greabu, "Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation". Revista de Chimie, vol. 68, no. 6, pp. 1201-1204, 2017. [online]. https://doi.org/10.37358/RC.17.6.5641

Text
Iulia Ioana Stanescu, Alexandra Totan, Florentina Rus, Daniela Miricescu, Brandusa Mocanu, Bogdan Calenic, Maria Greabu,
Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation,
Revista de Chimie,
Volume 68, Issue 6,
2017,
Pages 1201-1204,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.6.5641.
(https://revistadechimie.ro/Articles.asp?ID=5641)
Keywords: saliva; periodontal disease; gingival crevicular fluid

RIS
TY - JOUR
T1 - Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation
A1 - Stanescu, Iulia Ioana
A2 - Totan, Alexandra
A3 - Rus, Florentina
A4 - Miricescu, Daniela
A5 - Mocanu, Brandusa
A6 - Calenic, Bogdan
A7 - Greabu, Maria
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 6
SP - 1201
EP - 1204
UR - https://doi.org/10.37358/RC.17.6.5641
KW - saliva
KW - periodontal disease
KW - gingival crevicular fluid
ER -

BibTex
@article{RevCh2017P1201,
author = {Stanescu Iulia Ioana and Totan Alexandra and Rus Florentina and Miricescu Daniela and Mocanu Brandusa and Calenic Bogdan and Greabu Maria},
title = {Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation},
journal = {Revista de Chimie},
volume = {68},
number = {6},
pages = {1201-1204},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.6.5641},
url = {https://revistadechimie.ro/Articles.asp?ID=5641}
}

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