Skin Specific Cells and UVB Damage An experimental assessment

Pavel, Ioana Zinuca; Iftode, Oana Andrada; Pinzaru, Iulia; Coricovac, Dorina; Moaca, Alina; Farcas, Claudia; Simu, Sebastian Claudiu; Soica, Codruta; Dehelean, Cristina; Motoc, Andrei

Ioana Zinuca Pavel, Oana Andrada Iftode, Iulia Pinzaru, Dorina Coricovac, Alina Moaca, Claudia Farcas, Sebastian Claudiu Simu, Codruta Soica, Cristina Dehelean, Andrei Motoc

Skin Specific Cells and UVB Damage An experimental assessment

Abstract:

The alarming increased incidence of skin cancers is closely related to ultraviolet radiation exposure, known to induce cellular transformation in epidermal and dermal layers. The current study describes the behavior of normal (human keratinocytes - HaCat and fibroblasts -1BR3) and tumor cells (human - A375 and murine - B164A5 and B16-F0 - melanoma) after UVB irradiation. A dose of 40 mJ/cm2 (312 nm) led to a decrease of both normal and tumor cells viability in a post-exposure time dependent manner, the most statistically significant reduction being recorded at 24h post-exposure. Moreover, some changes in the shape of cells exposed to UVB were detected. Our results confirm the cytotoxic effects associated with UVB exposure and could be further employed to evaluate the photo-protective effects of different agents.

Keywords:
skin malignancies; irradiation; cells; viability

Issue: 2017, Volume 68, Issue 6

Pages: 1229-1233

Publication date: 2017/7/15

https://doi.org/10.37358/RC.17.6.5647

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
PAVEL, I.Z., IFTODE, O.A., PINZARU, I., CORICOVAC, D., MOACA, A., FARCAS, C., SIMU, S.C., SOICA, C., DEHELEAN, C., MOTOC, A., Skin Specific Cells and UVB Damage An experimental assessment, Rev. Chim., 68(6), 2017, 1229-1233.

Vancouver
Pavel IZ, Iftode OA, Pinzaru I, Coricovac D, Moaca A, Farcas C, Simu SC, Soica C, Dehelean C, Motoc A. Skin Specific Cells and UVB Damage An experimental assessment. Rev. Chim.[internet]. 2017 Jun;68(6):1229-1233. Available from: https://doi.org/10.37358/RC.17.6.5647

APA 6th edition
Pavel, I.Z., Iftode, O.A., Pinzaru, I., Coricovac, D., Moaca, A., Farcas, C.,... Motoc, A. (2017). Skin Specific Cells and UVB Damage An experimental assessment. Revista de Chimie, 68(6), 1229-1233. https://doi.org/10.37358/RC.17.6.5647

Harvard
Pavel, I.Z., Iftode, O.A., Pinzaru, I., Coricovac, D., Moaca, A., Farcas, C., Simu, S.C., Soica, C., Dehelean, C., Motoc, A. (2017). 'Skin Specific Cells and UVB Damage An experimental assessment', Revista de Chimie, 68(6), pp. 1229-1233. https://doi.org/10.37358/RC.17.6.5647

IEEE
I.Z. Pavel, O.A. Iftode, I. Pinzaru, D. Coricovac, A. Moaca, C. Farcas, S.C. Simu, C. Soica, C. Dehelean, A. Motoc, "Skin Specific Cells and UVB Damage An experimental assessment". Revista de Chimie, vol. 68, no. 6, pp. 1229-1233, 2017. [online]. https://doi.org/10.37358/RC.17.6.5647

Text
Ioana Zinuca Pavel, Oana Andrada Iftode, Iulia Pinzaru, Dorina Coricovac, Alina Moaca, Claudia Farcas, Sebastian Claudiu Simu, Codruta Soica, Cristina Dehelean, Andrei Motoc,
Skin Specific Cells and UVB Damage An experimental assessment,
Revista de Chimie,
Volume 68, Issue 6,
2017,
Pages 1229-1233,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.6.5647.
(https://revistadechimie.ro/Articles.asp?ID=5647)
Keywords: skin malignancies; irradiation; cells; viability

RIS
TY - JOUR
T1 - Skin Specific Cells and UVB Damage An experimental assessment
A1 - Pavel, Ioana Zinuca
A2 - Iftode, Oana Andrada
A3 - Pinzaru, Iulia
A4 - Coricovac, Dorina
A5 - Moaca, Alina
A6 - Farcas, Claudia
A7 - Simu, Sebastian Claudiu
A8 - Soica, Codruta
A9 - Dehelean, Cristina
A10 - Motoc, Andrei
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 6
SP - 1229
EP - 1233
UR - https://doi.org/10.37358/RC.17.6.5647
KW - skin malignancies
KW - irradiation
KW - cells
KW - viability
ER -

BibTex
@article{RevCh2017P1229,
author = {Pavel Ioana Zinuca and Iftode Oana Andrada and Pinzaru Iulia and Coricovac Dorina and Moaca Alina and Farcas Claudia and Simu Sebastian Claudiu and Soica Codruta and Dehelean Cristina and Motoc Andrei},
title = {Skin Specific Cells and UVB Damage An experimental assessment},
journal = {Revista de Chimie},
volume = {68},
number = {6},
pages = {1229-1233},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.6.5647},
url = {https://revistadechimie.ro/Articles.asp?ID=5647}
}

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