Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders

Chisnoiu, Andrea Maria; Pallag, Annamaria; Bodog, Florian Dorel; Juncar, Raluca Iulia; Chisnoiu, Radu Marcel; Sirbu, Vasile; Honiges, Ana; Juncar, Mihai

Andrea Maria Chisnoiu, Annamaria Pallag, Florian Dorel Bodog, Raluca Iulia Juncar, Radu Marcel Chisnoiu, Vasile Sirbu, Ana Honiges, Mihai Juncar

Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders

Abstract:

Oxidative stress is considered to have an important role in the pathogenesis of many inflammatory diseases. This investigation sought to determine whether the appliance of etiologic factors for temporomandibular joint disorder is associated with modified values of oxidative stress as measured by biomarkers in plasma. A case-control study design was used to compare oxidative stress biomarkers (malondialdehyde and glutathione) in plasma from Wistar rats with different etiologic factors (biomechanical stress, estrogen hormones and emotional stress), compared to non-temporomandibular joint controls. Etiologic factors were applied in five groups (n=10) of mature female Wistar rats, individually (biomechanical stress, estrogen hormones and emotional stress) in three groups or in combination for two groups (biomechanical stress-emotional stress and biomechanical stress-emotional stress). No factor applied for the control group. Blood samples were taken after 30 and 60 days of experiment. Malondialdehyde and glutathione levels in plasma were evaluated. The most important modifications in malondialdehyde levels were recorded for the fifth group (biomechanical stress-emotional stress) where values increased significantly from 30 to 60 days plasma analysis (p = 0.003). No statistical differences were recorded in glutathione plasmatic levels between control and experimental groups at 30 days analysis. At 60 days, glutathione plasmatic evaluation recorded higher values than control for all experimental groups. Our findings in this rat experimental model, clearly indicate that biomechanical stress, estrogen hormones and emotional stress, have an impact on oxidative stress development and consequently on the functionality of the temporomandibular joint in rats. Moreover combined actions of these factors, increase the oxidative stress phenomena on temporomandibular joint in rats.

Keywords:
biomechanical stress; emotional stress; estrogens hormones; oxidative markers; temporomandibular joint; free radicals

Issue: 2017, Volume 68, Issue 6

Pages: 1367-1370

Publication date: 2017/7/15

https://doi.org/10.37358/RC.17.6.5675

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CHISNOIU, A.M., PALLAG, A., BODOG, F.D., JUNCAR, R.I., CHISNOIU, R.M., SIRBU, V., HONIGES, A., JUNCAR, M., Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders, Rev. Chim., 68(6), 2017, 1367-1370.

Vancouver
Chisnoiu AM, Pallag A, Bodog FD, Juncar RI, Chisnoiu RM, Sirbu V, Honiges A, Juncar M. Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders. Rev. Chim.[internet]. 2017 Jun;68(6):1367-1370. Available from: https://doi.org/10.37358/RC.17.6.5675

APA 6th edition
Chisnoiu, A.M., Pallag, A., Bodog, F.D., Juncar, R.I., Chisnoiu, R.M., Sirbu, V., Honiges, A. & Juncar, M. (2017). Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders. Revista de Chimie, 68(6), 1367-1370. https://doi.org/10.37358/RC.17.6.5675

Harvard
Chisnoiu, A.M., Pallag, A., Bodog, F.D., Juncar, R.I., Chisnoiu, R.M., Sirbu, V., Honiges, A., Juncar, M. (2017). 'Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders', Revista de Chimie, 68(6), pp. 1367-1370. https://doi.org/10.37358/RC.17.6.5675

IEEE
A.M. Chisnoiu, A. Pallag, F.D. Bodog, R.I. Juncar, R.M. Chisnoiu, V. Sirbu, A. Honiges, M. Juncar, "Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders". Revista de Chimie, vol. 68, no. 6, pp. 1367-1370, 2017. [online]. https://doi.org/10.37358/RC.17.6.5675

Text
Andrea Maria Chisnoiu, Annamaria Pallag, Florian Dorel Bodog, Raluca Iulia Juncar, Radu Marcel Chisnoiu, Vasile Sirbu, Ana Honiges, Mihai Juncar,
Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders,
Revista de Chimie,
Volume 68, Issue 6,
2017,
Pages 1367-1370,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.6.5675.
(https://revistadechimie.ro/Articles.asp?ID=5675)
Keywords: biomechanical stress; emotional stress; estrogens hormones; oxidative markers; temporomandibular joint; free radicals

RIS
TY - JOUR
T1 - Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders
A1 - Chisnoiu, Andrea Maria
A2 - Pallag, Annamaria
A3 - Bodog, Florian Dorel
A4 - Juncar, Raluca Iulia
A5 - Chisnoiu, Radu Marcel
A6 - Sirbu, Vasile
A7 - Honiges, Ana
A8 - Juncar, Mihai
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 6
SP - 1367
EP - 1370
UR - https://doi.org/10.37358/RC.17.6.5675
KW - biomechanical stress
KW - emotional stress
KW - estrogens hormones
KW - oxidative markers
KW - temporomandibular joint
KW - free radicals
ER -

BibTex
@article{RevCh2017P1367,
author = {Chisnoiu Andrea Maria and Pallag Annamaria and Bodog Florian Dorel and Juncar Raluca Iulia and Chisnoiu Radu Marcel and Sirbu Vasile and Honiges Ana and Juncar Mihai},
title = {Study of the Plasmatic Oxidative Stress Markers in Temporomandibular Joint Disorders},
journal = {Revista de Chimie},
volume = {68},
number = {6},
pages = {1367-1370},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.6.5675},
url = {https://revistadechimie.ro/Articles.asp?ID=5675}
}

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