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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 9, 2014-2017

https://doi.org/10.37358/RC.17.9.5813

Jelena Savici, Oana Maria Boldura, Cornel Balta, Diana Brezovan, Florin Muselin, Calin Mircu, Claudia Borza, Marilena Motoc, Camelia Tulcan

Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland

Abstract:

This study was carried out to test the possibility of hexavalent chromium administration through drinking water to induce the structural damage in rat’s adrenal glands and the possibility of Hypericum perforatum extract to faith against chromium aggression. Chromium induced cellular stress was determined by the expression level assessment of the Bcl2 genes family, known to modulate the apoptotic pathway. Obtained results showed that exposure to chromium altered adrenal glands morphology, by induction of apoptosis. When Hypericum perforatum extract was administered expression level of Bcl2 genes and histological lesions in adrenal glands were significantly reduced.
Keywords:
chromium; adrenal gland; Aronia melanocarpa

Issue: 2017, Volume 68, Issue 9
Pages: 2014-2017
Publication date: 2017/10/15
https://doi.org/10.37358/RC.17.9.5813
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SAVICI, J., BOLDURA, O.M., BALTA, C., BREZOVAN, D., MUSELIN, F., MIRCU, C., BORZA, C., MOTOC, M., TULCAN, C., Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland, Rev. Chim., 68(9), 2017, 2014-2017.

Vancouver
Savici J, Boldura OM, Balta C, Brezovan D, Muselin F, Mircu C, Borza C, Motoc M, Tulcan C. Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland. Rev. Chim.[internet]. 2017 Sep;68(9):2014-2017. Available from: https://doi.org/10.37358/RC.17.9.5813


APA 6th edition
Savici, J., Boldura, O.M., Balta, C., Brezovan, D., Muselin, F., Mircu, C.,... Tulcan, C. (2017). Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland. Revista de Chimie, 68(9), 2014-2017. https://doi.org/10.37358/RC.17.9.5813


Harvard
Savici, J., Boldura, O.M., Balta, C., Brezovan, D., Muselin, F., Mircu, C., Borza, C., Motoc, M., Tulcan, C. (2017). 'Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland', Revista de Chimie, 68(9), pp. 2014-2017. https://doi.org/10.37358/RC.17.9.5813


IEEE
J. Savici, O.M. Boldura, C. Balta, D. Brezovan, F. Muselin, C. Mircu, C. Borza, M. Motoc, C. Tulcan, "Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland". Revista de Chimie, vol. 68, no. 9, pp. 2014-2017, 2017. [online]. https://doi.org/10.37358/RC.17.9.5813


Text
Jelena Savici, Oana Maria Boldura, Cornel Balta, Diana Brezovan, Florin Muselin, Calin Mircu, Claudia Borza, Marilena Motoc, Camelia Tulcan,
Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland,
Revista de Chimie,
Volume 68, Issue 9,
2017,
Pages 2014-2017,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.9.5813.
(https://revistadechimie.ro/Articles.asp?ID=5813)
Keywords: chromium; adrenal gland; Aronia melanocarpa


RIS
TY - JOUR
T1 - Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland
A1 - Savici, Jelena
A2 - Boldura, Oana Maria
A3 - Balta, Cornel
A4 - Brezovan, Diana
A5 - Muselin, Florin
A6 - Mircu, Calin
A7 - Borza, Claudia
A8 - Motoc, Marilena
A9 - Tulcan, Camelia
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 9
SP - 2014
EP - 2017
UR - https://doi.org/10.37358/RC.17.9.5813
KW - chromium
KW - adrenal gland
KW - Aronia melanocarpa
ER -


BibTex
@article{RevCh2017P2014,
author = {Savici Jelena and Boldura Oana Maria and Balta Cornel and Brezovan Diana and Muselin Florin and Mircu Calin and Borza Claudia and Motoc Marilena and Tulcan Camelia},
title = {Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland},
journal = {Revista de Chimie},
volume = {68},
number = {9},
pages = {2014-2017},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.9.5813},
url = {https://revistadechimie.ro/Articles.asp?ID=5813}
}
 
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