New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets

Bungau, Simona; Tit, Delia Mirela; Iovan, Ciprian; Copolovici, Lucian; Boscencu, Rica; Cioca, Gabriela; Copolovici, Dana

Simona Bungau, Delia Mirela Tit, Ciprian Iovan, Lucian Copolovici, Rica Boscencu, Gabriela Cioca, Dana Copolovici

New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets

Abstract:

The determination of the real concentration in different pharmaceutical drugs represents a very important goal of the pharmaceutical industry. The main aim of the study was to set up a simple, cheap and rapid method in order to determine both ascorbic and acetylsalicylic acid content of effervescent tablets that could be found on the pharmaceutical market, without preliminary separation or extraction. For this purpose, a very simple and reliable clock method based on two Landolt-type systems of reactions, based on potentiometric techniques, has been developed. The method has been tested on different effervescent tablets which contain ascorbic acid and acetylsalicylic acid in different mixture ratio.

Keywords:
ascorbic acid; acetylsalicylic acid; potentiometric method; Landolt system; effervescent tablets

Issue: 2017, Volume 68, Issue 11

Pages: 2495-2598

Publication date: 2017/12/15

https://doi.org/10.37358/RC.17.11.5914

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BUNGAU, S., TIT, D.M., IOVAN, C., COPOLOVICI, L., BOSCENCU, R., CIOCA, G., COPOLOVICI, D., New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets, Rev. Chim., 68(11), 2017, 2495-2598.

Vancouver
Bungau S, Tit DM, Iovan C, Copolovici L, Boscencu R, Cioca G, Copolovici D. New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets. Rev. Chim.[internet]. 2017 Nov;68(11):2495-2598. Available from: https://doi.org/10.37358/RC.17.11.5914

APA 6th edition
Bungau, S., Tit, D.M., Iovan, C., Copolovici, L., Boscencu, R., Cioca, G. & Copolovici, D. (2017). New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets. Revista de Chimie, 68(11), 2495-2598. https://doi.org/10.37358/RC.17.11.5914

Harvard
Bungau, S., Tit, D.M., Iovan, C., Copolovici, L., Boscencu, R., Cioca, G., Copolovici, D. (2017). 'New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets', Revista de Chimie, 68(11), pp. 2495-2598. https://doi.org/10.37358/RC.17.11.5914

IEEE
S. Bungau, D.M. Tit, C. Iovan, L. Copolovici, R. Boscencu, G. Cioca, D. Copolovici, "New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets". Revista de Chimie, vol. 68, no. 11, pp. 2495-2598, 2017. [online]. https://doi.org/10.37358/RC.17.11.5914

Text
Simona Bungau, Delia Mirela Tit, Ciprian Iovan, Lucian Copolovici, Rica Boscencu, Gabriela Cioca, Dana Copolovici,
New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets,
Revista de Chimie,
Volume 68, Issue 11,
2017,
Pages 2495-2598,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.11.5914.
(https://revistadechimie.ro/Articles.asp?ID=5914)
Keywords: ascorbic acid; acetylsalicylic acid; potentiometric method; Landolt system; effervescent tablets

RIS
TY - JOUR
T1 - New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets
A1 - Bungau, Simona
A2 - Tit, Delia Mirela
A3 - Iovan, Ciprian
A4 - Copolovici, Lucian
A5 - Boscencu, Rica
A6 - Cioca, Gabriela
A7 - Copolovici, Dana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 11
SP - 2495
EP - 2598
UR - https://doi.org/10.37358/RC.17.11.5914
KW - ascorbic acid
KW - acetylsalicylic acid
KW - potentiometric method
KW - Landolt system
KW - effervescent tablets
ER -

BibTex
@article{RevCh2017P2495,
author = {Bungau Simona and Tit Delia Mirela and Iovan Ciprian and Copolovici Lucian and Boscencu Rica and Cioca Gabriela and Copolovici Dana},
title = {New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets},
journal = {Revista de Chimie},
volume = {68},
number = {11},
pages = {2495-2598},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.11.5914},
url = {https://revistadechimie.ro/Articles.asp?ID=5914}
}

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