Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac

Rusu, Elena; Sarbu, Ionela; Mitache, Magdalena; Moldovan, Horatiu; Biris, Carmen Ioana; Vassu, Tatiana; Pelinescu, Diana

Elena Rusu, Ionela Sarbu, Magdalena Mitache, Horatiu Moldovan, Carmen Ioana Biris, Tatiana Vassu, Diana Pelinescu

Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac

Abstract:

The high frequency of occurrence of candidiasis as well as high mortality of patients with immunosuppression cause a tendency toward better understanding of Candida albicans species virulence factors and developing sensitive and specific diagnostic methods, and appropriate strategies of candidiasis treatment. In recent decades the incidence of fungal infections has alarming increases because of advanced medical treatments. In this study was analyzed possible ultrastructural changes of the species C. albicans cells following treatment with sodium diclofenac at various concentrations. Following treatment of C. albicans cells with sodium diclofenac 1 mM and 2 mM changes in the plasmalemma can be noticed, changes in the density of cell wall, disruption and necrotic appearance of the cytoplasm.

Keywords:
diclofenac; yeast; morphology; NSAID

Issue: 2017, Volume 68, Issue 11

Pages: 2566-2569

Publication date: 2017/12/15

https://doi.org/10.37358/RC.17.11.5929

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
RUSU, E., SARBU, I., MITACHE, M., MOLDOVAN, H., BIRIS, C.I., VASSU, T., PELINESCU, D., Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac, Rev. Chim., 68(11), 2017, 2566-2569.

Vancouver
Rusu E, Sarbu I, Mitache M, Moldovan H, Biris CI, Vassu T, Pelinescu D. Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac. Rev. Chim.[internet]. 2017 Nov;68(11):2566-2569. Available from: https://doi.org/10.37358/RC.17.11.5929

APA 6th edition
Rusu, E., Sarbu, I., Mitache, M., Moldovan, H., Biris, C.I., Vassu, T. & Pelinescu, D. (2017). Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac. Revista de Chimie, 68(11), 2566-2569. https://doi.org/10.37358/RC.17.11.5929

Harvard
Rusu, E., Sarbu, I., Mitache, M., Moldovan, H., Biris, C.I., Vassu, T., Pelinescu, D. (2017). 'Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac', Revista de Chimie, 68(11), pp. 2566-2569. https://doi.org/10.37358/RC.17.11.5929

IEEE
E. Rusu, I. Sarbu, M. Mitache, H. Moldovan, C.I. Biris, T. Vassu, D. Pelinescu, "Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac". Revista de Chimie, vol. 68, no. 11, pp. 2566-2569, 2017. [online]. https://doi.org/10.37358/RC.17.11.5929

Text
Elena Rusu, Ionela Sarbu, Magdalena Mitache, Horatiu Moldovan, Carmen Ioana Biris, Tatiana Vassu, Diana Pelinescu,
Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac,
Revista de Chimie,
Volume 68, Issue 11,
2017,
Pages 2566-2569,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.11.5929.
(https://revistadechimie.ro/Articles.asp?ID=5929)
Keywords: diclofenac; yeast; morphology; NSAID

RIS
TY - JOUR
T1 - Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac
A1 - Rusu, Elena
A2 - Sarbu, Ionela
A3 - Mitache, Magdalena
A4 - Moldovan, Horatiu
A5 - Biris, Carmen Ioana
A6 - Vassu, Tatiana
A7 - Pelinescu, Diana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 11
SP - 2566
EP - 2569
UR - https://doi.org/10.37358/RC.17.11.5929
KW - diclofenac
KW - yeast
KW - morphology
KW - NSAID
ER -

BibTex
@article{RevCh2017P2566,
author = {Rusu Elena and Sarbu Ionela and Mitache Magdalena and Moldovan Horatiu and Biris Carmen Ioana and Vassu Tatiana and Pelinescu Diana},
title = {Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac},
journal = {Revista de Chimie},
volume = {68},
number = {11},
pages = {2566-2569},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.11.5929},
url = {https://revistadechimie.ro/Articles.asp?ID=5929}
}

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