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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 1, 121-124

https://doi.org/10.37358/RC.18.1.6056

Iulia Pinzaru, Alina Heghes, Daniela Marti, Cristina Dehelean, Dorina Coricovac, Alina Moaca, Mihaela Moatar, Dorin Came

Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments

Abstract:

The present study was aimed to evaluate total phenols, flavonoid and flavonols content and to assess relative cytotoxicity of Medicago sativa hydro-alcoholic and alcoholic leaves and stems extracts on human lung carcinoma (A549) and human breast carcinoma (MDA-MB-231). All extracts tested have proven to be rich in hydroxylated compounds, larger amounts of phenolic compounds were found in extracts obtained using 70% ethanol, a proper polar solvent for this molecule types. Evaluation of antioxidant activity reveals values all most comparable with the ones of ascorbic acid. The extracts induced a cytotoxic effect on both tumor cell lines in a concentration-depend manner.
Keywords:
alfalfa; phenols; flavonoids; antioxidant activity; cytotoxicity

Issue: 2018, Volume 69, Issue 1
Pages: 121-124
Publication date: 2018/2/15
https://doi.org/10.37358/RC.18.1.6056
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
PINZARU, I., HEGHES, A., MARTI, D., DEHELEAN, C., CORICOVAC, D., MOACA, A., MOATAR, M., CAME, D., Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments, Rev. Chim., 69(1), 2018, 121-124.

Vancouver
Pinzaru I, Heghes A, Marti D, Dehelean C, Coricovac D, Moaca A, Moatar M, Came D. Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments. Rev. Chim.[internet]. 2018 Jan;69(1):121-124. Available from: https://doi.org/10.37358/RC.18.1.6056


APA 6th edition
Pinzaru, I., Heghes, A., Marti, D., Dehelean, C., Coricovac, D., Moaca, A., Moatar, M. & Came, D. (2018). Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments. Revista de Chimie, 69(1), 121-124. https://doi.org/10.37358/RC.18.1.6056


Harvard
Pinzaru, I., Heghes, A., Marti, D., Dehelean, C., Coricovac, D., Moaca, A., Moatar, M., Came, D. (2018). 'Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments', Revista de Chimie, 69(1), pp. 121-124. https://doi.org/10.37358/RC.18.1.6056


IEEE
I. Pinzaru, A. Heghes, D. Marti, C. Dehelean, D. Coricovac, A. Moaca, M. Moatar, D. Came, "Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments". Revista de Chimie, vol. 69, no. 1, pp. 121-124, 2018. [online]. https://doi.org/10.37358/RC.18.1.6056


Text
Iulia Pinzaru, Alina Heghes, Daniela Marti, Cristina Dehelean, Dorina Coricovac, Alina Moaca, Mihaela Moatar, Dorin Came,
Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments,
Revista de Chimie,
Volume 69, Issue 1,
2018,
Pages 121-124,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.1.6056.
(https://revistadechimie.ro/Articles.asp?ID=6056)
Keywords: alfalfa; phenols; flavonoids; antioxidant activity; cytotoxicity


RIS
TY - JOUR
T1 - Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments
A1 - Pinzaru, Iulia
A2 - Heghes, Alina
A3 - Marti, Daniela
A4 - Dehelean, Cristina
A5 - Coricovac, Dorina
A6 - Moaca, Alina
A7 - Moatar, Mihaela
A8 - Came, Dorin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 1
SP - 121
EP - 124
UR - https://doi.org/10.37358/RC.18.1.6056
KW - alfalfa
KW - phenols
KW - flavonoids
KW - antioxidant activity
KW - cytotoxicity
ER -


BibTex
@article{RevCh2018P121,
author = {Pinzaru Iulia and Heghes Alina and Marti Daniela and Dehelean Cristina and Coricovac Dorina and Moaca Alina and Moatar Mihaela and Came Dorin},
title = {Therapeutically Potential of Medicago sativa Extracts. Chemical and in vitro assessments},
journal = {Revista de Chimie},
volume = {69},
number = {1},
pages = {121-124},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.1.6056},
url = {https://revistadechimie.ro/Articles.asp?ID=6056}
}
 
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