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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 1, 136-139

https://doi.org/10.37358/RC.18.1.6059

Andra Maria Cocolos, Nicoleta Dumitru, Eugenia Nedeltcheva Petrova, Ion Cocolos, Mirela Tiglis, Razvan Florin Ion Dragomirescu, Maria Olaru, Alina Dumitru, Adina Mariana Ghemigian

Endocrine Disrupting Chemicals - the X Factor in Different Pathologies

Abstract:

Endocrine disruptors (ED) are exogenous agents that interfere with the normal function of the endocrine system and they are considered environmental chemicals with estrogen-like and/or anti-androgenic activity with important impact on the reproductive axis. They act via nuclear receptors, non-nuclear steroid receptors, nonsteroidal receptors, orphan receptors, and different enzyme pathways involved in the biosynthesis and/or metabolism of steroids. The molecules identified as ED and sources of exposure are diverse and vary worldwide, including from natural chemicals found in human and animal food (the main source) up to synthetic chemicals, such as as solvents, plasticizers, pesticides, fungicides, pharmaceuticals etc. ED are incriminated in the occurrence of malignant tumors, birth defects, attention deficit disorders, cognitive impairment, brain development, deformations of the body (including limbs), disturbance of sexual development, menstrual irregularity, precocious puberty, feminizing or masculinizing effects, abortion, not least obesity and decreased fertility. The principles of action are still studied and controversial, therefore, it is difficult to determine the minimum level at which adverse effect occurs and further studies are required.
Keywords:
endocrine disruptors; endocrine systems; sources; pathology; outcome

Issue: 2018, Volume 69, Issue 1
Pages: 136-139
Publication date: 2018/2/15
https://doi.org/10.37358/RC.18.1.6059
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
COCOLOS, A.M., DUMITRU, N., PETROVA, E.N., COCOLOS, I., TIGLIS, M., DRAGOMIRESCU, R.F.I., OLARU, M., DUMITRU, A., GHEMIGIAN, A.M., Endocrine Disrupting Chemicals - the X Factor in Different Pathologies, Rev. Chim., 69(1), 2018, 136-139.

Vancouver
Cocolos AM, Dumitru N, Petrova EN, Cocolos I, Tiglis M, Dragomirescu RFI, Olaru M, Dumitru A, Ghemigian AM. Endocrine Disrupting Chemicals - the X Factor in Different Pathologies. Rev. Chim.[internet]. 2018 Jan;69(1):136-139. Available from: https://doi.org/10.37358/RC.18.1.6059


APA 6th edition
Cocolos, A.M., Dumitru, N., Petrova, E.N., Cocolos, I., Tiglis, M., Dragomirescu, R.F.I.,... Ghemigian, A.M. (2018). Endocrine Disrupting Chemicals - the X Factor in Different Pathologies. Revista de Chimie, 69(1), 136-139. https://doi.org/10.37358/RC.18.1.6059


Harvard
Cocolos, A.M., Dumitru, N., Petrova, E.N., Cocolos, I., Tiglis, M., Dragomirescu, R.F.I., Olaru, M., Dumitru, A., Ghemigian, A.M. (2018). 'Endocrine Disrupting Chemicals - the X Factor in Different Pathologies', Revista de Chimie, 69(1), pp. 136-139. https://doi.org/10.37358/RC.18.1.6059


IEEE
A.M. Cocolos, N. Dumitru, E.N. Petrova, I. Cocolos, M. Tiglis, R.F.I. Dragomirescu, M. Olaru, A. Dumitru, A.M. Ghemigian, "Endocrine Disrupting Chemicals - the X Factor in Different Pathologies". Revista de Chimie, vol. 69, no. 1, pp. 136-139, 2018. [online]. https://doi.org/10.37358/RC.18.1.6059


Text
Andra Maria Cocolos, Nicoleta Dumitru, Eugenia Nedeltcheva Petrova, Ion Cocolos, Mirela Tiglis, Razvan Florin Ion Dragomirescu, Maria Olaru, Alina Dumitru, Adina Mariana Ghemigian,
Endocrine Disrupting Chemicals - the X Factor in Different Pathologies,
Revista de Chimie,
Volume 69, Issue 1,
2018,
Pages 136-139,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.1.6059.
(https://revistadechimie.ro/Articles.asp?ID=6059)
Keywords: endocrine disruptors; endocrine systems; sources; pathology; outcome


RIS
TY - JOUR
T1 - Endocrine Disrupting Chemicals - the X Factor in Different Pathologies
A1 - Cocolos, Andra Maria
A2 - Dumitru, Nicoleta
A3 - Petrova, Eugenia Nedeltcheva
A4 - Cocolos, Ion
A5 - Tiglis, Mirela
A6 - Dragomirescu, Razvan Florin Ion
A7 - Olaru, Maria
A8 - Dumitru, Alina
A9 - Ghemigian, Adina Mariana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 1
SP - 136
EP - 139
UR - https://doi.org/10.37358/RC.18.1.6059
KW - endocrine disruptors
KW - endocrine systems
KW - sources
KW - pathology
KW - outcome
ER -


BibTex
@article{RevCh2018P136,
author = {Cocolos Andra Maria and Dumitru Nicoleta and Petrova Eugenia Nedeltcheva and Cocolos Ion and Tiglis Mirela and Dragomirescu Razvan Florin Ion and Olaru Maria and Dumitru Alina and Ghemigian Adina Mariana},
title = {Endocrine Disrupting Chemicals - the X Factor in Different Pathologies},
journal = {Revista de Chimie},
volume = {69},
number = {1},
pages = {136-139},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.1.6059},
url = {https://revistadechimie.ro/Articles.asp?ID=6059}
}
 
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