ABOUT INDEXING BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER AUTHORS'S SUBSCRIPTIONS AUTHORS'S PAGE PUBLISHING ETHICS NEWS, EVENTS
REVISTA DE CHIMIE
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN 0034-7752
ISSN 2668-8212 (Online)
Journal Metrics
* Impact Factor 2018-19: 1.605
* 5-Year IF: 1.34
* CiteScore: 1.23
* SNIP: 0.710
* SJR: 0.294
(academic-accelerator.com)
Crossref Member Badge
 DOI  logo

Chemistry Magazine

LATEST ISSUE >>>

   Volume 71, 2020
   Volume 70, 2019
   Volume 69, 2018
   Volume 68, 2017
   Volume 67, 2016
   Volume 66, 2015
   Volume 65, 2014
   Volume 64, 2013
   Volume 63, 2012
   Volume 62, 2011
   Volume 61, 2010
   Volume 60, 2009
   Volume 59, 2008
   Volume 58, 2007
   Volume 57, 2006
   Volume 56, 2005
   Volume 55, 2004
   Volume 54, 2003
   Volume 53, 2002
 
<<<< back

Revista de Chimie, Volume 69, Issue 1, pp. 169-171 (2018)
https://doi.org/10.37358/RC.18.1.6067

Mihaela Pertea, Vladimir Poroch, Oxana Madalina Grosu, Sorinel Lunca

Study on Epinephrine Used in Local Anesthesia Controversy and certainty

Abstract:

Epinephrine (adrenaline) - C9H13NO3 - was synthesized for the first time by Fredrich Stelz in 1904 from phenylalanine. After a hydrolysis and decarboxylation process, active dopamine is obtained. Following the pathway of other hydroxylation followed by N-methylation, epinephrine synthesis is achieved. Epinephrine has initially been administrated together with procaine in local anesthesia in hand surgery. Epinephrine has been considered to be one of causes of ischemia and necrosis in hand and especially fingers surgery. Over time, studies have shown the efficacy and safety of using lidocaine-associated epinephrine in local hand surgery anesthesia. Numerous advantages regarding the use of lidocaine 1% with epinephrine, solution at a concentration of 1:100,000 have been reported, starting with increasing the duration of anesthesia, avoiding the use of tourniquet, leading to increased patient comfort and to the advantage of a much lower cost in terms of surgery as a whole. Our study group consisted of fifty patients with hand and fingers different patologies. In all cases surgery was performed under local anesthesia using lidocaine 1% with epinephrine, solution at a concentration of 1:100,000. The decrease of doses mentioned in the literature was attempted and in some cases the decrease was up to 30%. There have not been reported any ischemic or necrosis complication in the immediate postoperative period.
Keywords:
lidocaine; epinephrine; local anesthesia; hand surgery

Issue: 2018 Volume 69, Number 1
Pages: 169-171
https://doi.org/10.37358/RC.18.1.6067
download pdf   Download Pdf Article
Citation Styles
Cite this article as:
PERTEA, M., POROCH, V., GROSU, O.M., LUNCA, S., Rev.Chim., 69, no. 1, 2018, p. 169

Vancouver
Pertea M, Poroch V, Grosu OM, Lunca S. Study on Epinephrine Used in Local Anesthesia Controversy and certainty. Rev. Chim.[internet]. 2018 Jan;69(1):169-171. Available from: https://doi.org/10.37358/RC.18.1.6067


APA 6th edition
Pertea, M., Poroch, V., Grosu, O.M. & Lunca, S. (2018). Study on Epinephrine Used in Local Anesthesia Controversy and certainty. Revista de Chimie, 69(1), 169-171. https://doi.org/10.37358/RC.18.1.6067


Harvard
Pertea, M., Poroch, V., Grosu, O.M., Lunca, S. (2018). 'Study on Epinephrine Used in Local Anesthesia Controversy and certainty', Revista de Chimie, 69(1), pp. 169-171. https://doi.org/10.37358/RC.18.1.6067


IEEE
M. Pertea, V. Poroch, O.M. Grosu, S. Lunca, "Study on Epinephrine Used in Local Anesthesia Controversy and certainty". Revista de Chimie, vol. 69, no. 1, pp. 169-171, 2018. [online]. https://doi.org/10.37358/RC.18.1.6067


Text
Mihaela Pertea, Vladimir Poroch, Oxana Madalina Grosu, Sorinel Lunca,
Study on Epinephrine Used in Local Anesthesia Controversy and certainty,
Revista de Chimie,
Volume 69, Issue 1,
2018,
Pages 169-171,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.1.6067.
(https://revistadechimie.ro/Articles.asp?ID=6067)
Keywords: lidocaine; epinephrine; local anesthesia; hand surgery


RIS
TY - JOUR
T1 - Study on Epinephrine Used in Local Anesthesia Controversy and certainty
A1 - Pertea, Mihaela
A2 - Poroch, Vladimir
A3 - Grosu, Oxana Madalina
A4 - Lunca, Sorinel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 1
SP - 169
EP - 171
UR - https://doi.org/10.37358/RC.18.1.6067
KW - lidocaine
KW - epinephrine
KW - local anesthesia
KW - hand surgery
ER -


BibTex
@article{RevCh2018P169,
author = {Pertea Mihaela and Poroch Vladimir and Grosu Oxana Madalina and Lunca Sorinel},
title = {Study on Epinephrine Used in Local Anesthesia Controversy and certainty},
journal = {Revista de Chimie},
volume = {69},
number = {1},
pages = {169-171},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.1.6067},
url = {https://revistadechimie.ro/Articles.asp?ID=6067}
}
 
Views number: 142    |     Downloads number: 27  
<<<< back
 
PUBLISHING SECTION
Author Guidelines
 * Ghidul Autorului (ro)
 * Paper Drafting
 * Paper Template
 * Paper Submission
 * Author Payments
 * Publishing Ethics
Submit Paper
Author's Page
  Search Authors
  News, Events
 chimie
*REVISTA DE CHIMIE - 70 de ani de aparitie neintrerupta*

Un eveniment special pentru comunitatea stiintifica din Romania va fi organizat in data de
4 martie 2020
Hotel Hilton Athenee Palace Bucuresti
Sala Regina Maria
ora 9.30.

Va asteptam.
 Chemistry Conferences Conferences of Contemporary Chemistry
 Publicatii de Chimie Publicatii de Chimie in Romania.
Scurt istoric
 BIBLIOTECA CHIMIEI Biblioteca Chimiei
 Materiale Plastice Materiale Plastice