Pal Fodor, Raluca Fodor, Arpad Solyom, Cornel Catoi, Flaviu Tabaran, Radu Lacatus, Cristian Trambitas, Bogdan Cordos, Tiberiu Bataga
Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model
Abstract:
Currently, microfracturing is the most commonly used cartilage repair procedure in cartilage defects. Our aim was to study the mechanism of in vivo cartilage repair in case of full-thickness articular cartilage damage of the knee using a three-dimensional matrix implanted without any preseeded cells in the defect. We also investigated whether platelet-rich plasma application after microfracture procedure of the knee is associated with improved outcome compared with traditional microfracture treatment alone in a rabbit model. Histological examination of the chondral defects, revealed the largest amount of new tissue with hyaline-like cartilage features in Hyalofast group. At 12 weeks from implantation of the Hyalofast scaffold demonstrated complete filling of the defect with hyaline cartilage in admixture with the scaffold and bone metaplasia in the deepest areas. In the PRP group, complete filling of the defect with an admixture of fibrous and hyaline-like cartilage tissue appeared with a discreet tendency of endochondral ossification. We confirmed the superiority of the autologous matrix-induced chondrogenesis compared to microfracture and PRP or microfracture alone in case of full-thickness articular cartilage damage of the knee.
Cite this article as: FODOR, P., FODOR, R., SOLYOM, A., CATOI, C., TABARAN, F., LACATUS, R., TRAMBITAS, C., CORDOS, B., BATAGA, T., Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model, Rev. Chim., 69(4), 2018, 894-900.
Vancouver Fodor P, Fodor R, Solyom A, Catoi C, Tabaran F, Lacatus R, Trambitas C, Cordos B, Bataga T. Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model. Rev. Chim.[internet]. 2018 Apr;69(4):894-900. Available from: https://doi.org/10.37358/RC.18.4.6223
APA 6th edition Fodor, P., Fodor, R., Solyom, A., Catoi, C., Tabaran, F., Lacatus, R.,... Bataga, T. (2018). Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model. Revista de Chimie, 69(4), 894-900. https://doi.org/10.37358/RC.18.4.6223
Harvard Fodor, P., Fodor, R., Solyom, A., Catoi, C., Tabaran, F., Lacatus, R., Trambitas, C., Cordos, B., Bataga, T. (2018). 'Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model', Revista de Chimie, 69(4), pp. 894-900. https://doi.org/10.37358/RC.18.4.6223
IEEE P. Fodor, R. Fodor, A. Solyom, C. Catoi, F. Tabaran, R. Lacatus, C. Trambitas, B. Cordos, T. Bataga, "Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model". Revista de Chimie, vol. 69, no. 4, pp. 894-900, 2018. [online]. https://doi.org/10.37358/RC.18.4.6223
Text Pal Fodor, Raluca Fodor, Arpad Solyom, Cornel Catoi, Flaviu Tabaran, Radu Lacatus, Cristian Trambitas, Bogdan Cordos, Tiberiu Bataga, Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model, Revista de Chimie, Volume 69, Issue 4, 2018, Pages 894-900, ISSN 2668-8212, https://doi.org/10.37358/RC.18.4.6223. (https://revistadechimie.ro/Articles.asp?ID=6223) Keywords: autologous matrix-induced chondrogenesis; hyaline cartilage; microfracture; platelet-rich plasma
RIS TY - JOUR T1 - Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model A1 - Fodor, Pal A2 - Fodor, Raluca A3 - Solyom, Arpad A4 - Catoi, Cornel A5 - Tabaran, Flaviu A6 - Lacatus, Radu A7 - Trambitas, Cristian A8 - Cordos, Bogdan A9 - Bataga, Tiberiu JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2018 VL - 69 IS - 4 SP - 894 EP - 900 UR - https://doi.org/10.37358/RC.18.4.6223 KW - autologous matrix-induced chondrogenesis KW - hyaline cartilage KW - microfracture KW - platelet-rich plasma ER -
BibTex @article{RevCh2018P894, author = {Fodor Pal and Fodor Raluca and Solyom Arpad and Catoi Cornel and Tabaran Flaviu and Lacatus Radu and Trambitas Cristian and Cordos Bogdan and Bataga Tiberiu}, title = {Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model}, journal = {Revista de Chimie}, volume = {69}, number = {4}, pages = {894-900}, year = {2018}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.18.4.6223}, url = {https://revistadechimie.ro/Articles.asp?ID=6223} }
