Serban Balanescu, Violeta Claudia Bojinca, Adrian Iancu, Mihai Bojinca, Andra Balanescu
Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?
Abstract:
Calcium and vitamin D are prescribed in women with osteopenia-osteoporosis to prevent fractures. These bone events increase morbidity and mortality justifying therapy to prevent bone loss. These elderly patients also have cardiovascular risk factors, atherosclerosis and vascular calcifications. Multiple trials demonstrated a relationship between the latter, coronary events and cardiovascular mortality. In these patients, ectopic tissue mineralization may worsen cardiovascular outcome. Calcium intake correlates neither with serum calcium, vascular calcification nor cardiovascular events. However serum calcium-phosphate product is related to vascular calcification and outcome. The main cause for vascular calcification is systemic inflammation and local atherosclerotic process with specific interactions between macrophages and smooth muscle cells. This review examines calcium intake, serum calcium concentration, systemic and vascular inflammation, the mechanisms of vascular calcification and their impact on cardiovascular outcome.
Keywords: calcium and vitamin D supplements; vascular calcifications; cardiovascular risk
Cite this article as: BALANESCU, S., BOJINCA, V.C., IANCU, A., BOJINCA, M., BALANESCU, A., Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?, Rev. Chim., 69(4), 2018, 956-960.
Vancouver Balanescu S, Bojinca VC, Iancu A, Bojinca M, Balanescu A. Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?. Rev. Chim.[internet]. 2018 Apr;69(4):956-960. Available from: https://doi.org/10.37358/RC.18.4.6236
APA 6th edition Balanescu, S., Bojinca, V.C., Iancu, A., Bojinca, M. & Balanescu, A. (2018). Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?. Revista de Chimie, 69(4), 956-960. https://doi.org/10.37358/RC.18.4.6236
Harvard Balanescu, S., Bojinca, V.C., Iancu, A., Bojinca, M., Balanescu, A. (2018). 'Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?', Revista de Chimie, 69(4), pp. 956-960. https://doi.org/10.37358/RC.18.4.6236
IEEE S. Balanescu, V.C. Bojinca, A. Iancu, M. Bojinca, A. Balanescu, "Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?". Revista de Chimie, vol. 69, no. 4, pp. 956-960, 2018. [online]. https://doi.org/10.37358/RC.18.4.6236
Text Serban Balanescu, Violeta Claudia Bojinca, Adrian Iancu, Mihai Bojinca, Andra Balanescu, Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?, Revista de Chimie, Volume 69, Issue 4, 2018, Pages 956-960, ISSN 2668-8212, https://doi.org/10.37358/RC.18.4.6236. (https://revistadechimie.ro/Articles.asp?ID=6236) Keywords: calcium and vitamin D supplements; vascular calcifications; cardiovascular risk
RIS TY - JOUR T1 - Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk? A1 - Balanescu, Serban A2 - Bojinca, Violeta Claudia A3 - Iancu, Adrian A4 - Bojinca, Mihai A5 - Balanescu, Andra JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2018 VL - 69 IS - 4 SP - 956 EP - 960 UR - https://doi.org/10.37358/RC.18.4.6236 KW - calcium and vitamin D supplements KW - vascular calcifications KW - cardiovascular risk ER -
BibTex @article{RevCh2018P956, author = {Balanescu Serban and Bojinca Violeta Claudia and Iancu Adrian and Bojinca Mihai and Balanescu Andra}, title = {Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?}, journal = {Revista de Chimie}, volume = {69}, number = {4}, pages = {956-960}, year = {2018}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.18.4.6236}, url = {https://revistadechimie.ro/Articles.asp?ID=6236} }
