Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?

Balanescu, Serban; Bojinca, Violeta Claudia; Iancu, Adrian; Bojinca, Mihai; Balanescu, Andra

Serban Balanescu, Violeta Claudia Bojinca, Adrian Iancu, Mihai Bojinca, Andra Balanescu

Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?

Abstract:

Calcium and vitamin D are prescribed in women with osteopenia-osteoporosis to prevent fractures. These bone events increase morbidity and mortality justifying therapy to prevent bone loss. These elderly patients also have cardiovascular risk factors, atherosclerosis and vascular calcifications. Multiple trials demonstrated a relationship between the latter, coronary events and cardiovascular mortality. In these patients, ectopic tissue mineralization may worsen cardiovascular outcome. Calcium intake correlates neither with serum calcium, vascular calcification nor cardiovascular events. However serum calcium-phosphate product is related to vascular calcification and outcome. The main cause for vascular calcification is systemic inflammation and local atherosclerotic process with specific interactions between macrophages and smooth muscle cells. This review examines calcium intake, serum calcium concentration, systemic and vascular inflammation, the mechanisms of vascular calcification and their impact on cardiovascular outcome.

Keywords:
calcium and vitamin D supplements; vascular calcifications; cardiovascular risk

Issue: 2018, Volume 69, Issue 4

Pages: 956-960

Publication date: 2018/5/15

https://doi.org/10.37358/RC.18.4.6236

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BALANESCU, S., BOJINCA, V.C., IANCU, A., BOJINCA, M., BALANESCU, A., Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?, Rev. Chim., 69(4), 2018, 956-960.

Vancouver
Balanescu S, Bojinca VC, Iancu A, Bojinca M, Balanescu A. Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?. Rev. Chim.[internet]. 2018 Apr;69(4):956-960. Available from: https://doi.org/10.37358/RC.18.4.6236

APA 6th edition
Balanescu, S., Bojinca, V.C., Iancu, A., Bojinca, M. & Balanescu, A. (2018). Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?. Revista de Chimie, 69(4), 956-960. https://doi.org/10.37358/RC.18.4.6236

Harvard
Balanescu, S., Bojinca, V.C., Iancu, A., Bojinca, M., Balanescu, A. (2018). 'Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?', Revista de Chimie, 69(4), pp. 956-960. https://doi.org/10.37358/RC.18.4.6236

IEEE
S. Balanescu, V.C. Bojinca, A. Iancu, M. Bojinca, A. Balanescu, "Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?". Revista de Chimie, vol. 69, no. 4, pp. 956-960, 2018. [online]. https://doi.org/10.37358/RC.18.4.6236

Text
Serban Balanescu, Violeta Claudia Bojinca, Adrian Iancu, Mihai Bojinca, Andra Balanescu,
Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?,
Revista de Chimie,
Volume 69, Issue 4,
2018,
Pages 956-960,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.4.6236.
(https://revistadechimie.ro/Articles.asp?ID=6236)
Keywords: calcium and vitamin D supplements; vascular calcifications; cardiovascular risk

RIS
TY - JOUR
T1 - Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?
A1 - Balanescu, Serban
A2 - Bojinca, Violeta Claudia
A3 - Iancu, Adrian
A4 - Bojinca, Mihai
A5 - Balanescu, Andra
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 4
SP - 956
EP - 960
UR - https://doi.org/10.37358/RC.18.4.6236
KW - calcium and vitamin D supplements
KW - vascular calcifications
KW - cardiovascular risk
ER -

BibTex
@article{RevCh2018P956,
author = {Balanescu Serban and Bojinca Violeta Claudia and Iancu Adrian and Bojinca Mihai and Balanescu Andra},
title = {Postmenopausal Calcium and Vitamin D Supplements Controversy: Do They Increase Cardiovascular Risk?},
journal = {Revista de Chimie},
volume = {69},
number = {4},
pages = {956-960},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.4.6236},
url = {https://revistadechimie.ro/Articles.asp?ID=6236}
}

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