Hyponatremia in Patients with Heart Failure: a Prognostic Marker

Diaconu, Camelia Cristina; Manea, Maria; Iancu, Mihaela Adela; Stanescu, Ana Maria Alexandra; Socea, Bogdan; Spinu, Dan Arsenie; Marcu, Dragos; Bratu, Ovidiu Gabriel

Camelia Cristina Diaconu, Maria Manea, Mihaela Adela Iancu, Ana Maria Alexandra Stanescu, Bogdan Socea, Dan Arsenie Spinu, Dragos Marcu, Ovidiu Gabriel Bratu

Hyponatremia in Patients with Heart Failure: a Prognostic Marker

Abstract:

Due to the high prevalence of cardiovascular diseases and better treatment strategies, with increased survival, heart failure is a condition with increasing prevalence, especially in developed countries. Heart failure patients often present electrolytic disorders, the most frequent one being hyponatremia. The objective of the study was to evaluate the frequency of hyponatremia in patients with chronic heart failure hospitalized in the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest and to assess the clinical and paraclinical correlations, as well as prognostic implications of hyponatremia in these patients. We performed an observational retrospective study on 400 chronic heart failure patients hospitalized between January 1st 2014 and August 31st 2015. From these patients, 60 patients have been diagnosed with hyponatremia (defined as a serum natrium [135 mEq/L) and represented our group of study. The values of the serum natrium at admission in the study group ranged between 110-132 mmol/L. Most patients had advanced heart failure, according to NYHA classes’ classification. The proportion of patients discharged with persistent hyponatremia was 48.33%, lower than the patients discharged with corrected serum sodium (51.67%), indicating an effective treatment of hyponatremia during hospitalization. The mortality rate during hospitalization in patients with corrected hyponatremia was 8.33%, smaller than the mortality rate in patients with persistent hyponatremia despite the correct administration of hydroelectrolytic rebalancing treatment (18.33%). Persistent hyponatremia may be considered a marker of a poor prognosis in hospitalized heart failure patients.

Keywords:
hyponatremia; heart failure; electrolytic disorders; diuretics; mortality

Issue: 2018, Volume 69, Issue 5

Pages: 1071-1074

Publication date: 2018/6/15

https://doi.org/10.37358/RC.18.5.6263

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
DIACONU, C.C., MANEA, M., IANCU, M.A., STANESCU, A.M.A., SOCEA, B., SPINU, D.A., MARCU, D., BRATU, O.G., Hyponatremia in Patients with Heart Failure: a Prognostic Marker, Rev. Chim., 69(5), 2018, 1071-1074.

Vancouver
Diaconu CC, Manea M, Iancu MA, Stanescu AMA, Socea B, Spinu DA, Marcu D, Bratu OG. Hyponatremia in Patients with Heart Failure: a Prognostic Marker. Rev. Chim.[internet]. 2018 May;69(5):1071-1074. Available from: https://doi.org/10.37358/RC.18.5.6263

APA 6th edition
Diaconu, C.C., Manea, M., Iancu, M.A., Stanescu, A.M.A., Socea, B., Spinu, D.A., Marcu, D. & Bratu, O.G. (2018). Hyponatremia in Patients with Heart Failure: a Prognostic Marker. Revista de Chimie, 69(5), 1071-1074. https://doi.org/10.37358/RC.18.5.6263

Harvard
Diaconu, C.C., Manea, M., Iancu, M.A., Stanescu, A.M.A., Socea, B., Spinu, D.A., Marcu, D., Bratu, O.G. (2018). 'Hyponatremia in Patients with Heart Failure: a Prognostic Marker', Revista de Chimie, 69(5), pp. 1071-1074. https://doi.org/10.37358/RC.18.5.6263

IEEE
C.C. Diaconu, M. Manea, M.A. Iancu, A.M.A. Stanescu, B. Socea, D.A. Spinu, D. Marcu, O.G. Bratu, "Hyponatremia in Patients with Heart Failure: a Prognostic Marker". Revista de Chimie, vol. 69, no. 5, pp. 1071-1074, 2018. [online]. https://doi.org/10.37358/RC.18.5.6263

Text
Camelia Cristina Diaconu, Maria Manea, Mihaela Adela Iancu, Ana Maria Alexandra Stanescu, Bogdan Socea, Dan Arsenie Spinu, Dragos Marcu, Ovidiu Gabriel Bratu,
Hyponatremia in Patients with Heart Failure: a Prognostic Marker,
Revista de Chimie,
Volume 69, Issue 5,
2018,
Pages 1071-1074,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.5.6263.
(https://revistadechimie.ro/Articles.asp?ID=6263)
Keywords: hyponatremia; heart failure; electrolytic disorders; diuretics; mortality

RIS
TY - JOUR
T1 - Hyponatremia in Patients with Heart Failure: a Prognostic Marker
A1 - Diaconu, Camelia Cristina
A2 - Manea, Maria
A3 - Iancu, Mihaela Adela
A4 - Stanescu, Ana Maria Alexandra
A5 - Socea, Bogdan
A6 - Spinu, Dan Arsenie
A7 - Marcu, Dragos
A8 - Bratu, Ovidiu Gabriel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 5
SP - 1071
EP - 1074
UR - https://doi.org/10.37358/RC.18.5.6263
KW - hyponatremia
KW - heart failure
KW - electrolytic disorders
KW - diuretics
KW - mortality
ER -

BibTex
@article{RevCh2018P1071,
author = {Diaconu Camelia Cristina and Manea Maria and Iancu Mihaela Adela and Stanescu Ana Maria Alexandra and Socea Bogdan and Spinu Dan Arsenie and Marcu Dragos and Bratu Ovidiu Gabriel},
title = {Hyponatremia in Patients with Heart Failure: a Prognostic Marker},
journal = {Revista de Chimie},
volume = {69},
number = {5},
pages = {1071-1074},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.5.6263},
url = {https://revistadechimie.ro/Articles.asp?ID=6263}
}

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