A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects

Balan, Daniela G.; Sianu, Dan Piperea; Stanescu, Iulia I.; Ionescu, Dorin; Balcangiu, Andra Elena Stroescu; Raducu, Laura; Stoicescu, Silvia Maria; Ceau, Adela M.; Tiliscan, Catalin; Nimigean, Vanda Roxana; Tarmure, Viorica; Croitoru, Alexandru G.

Daniela G. Balan, Dan Piperea Sianu, Iulia I. Stanescu, Dorin Ionescu, Andra Elena Stroescu Balcangiu, Laura Raducu, Silvia Maria Stoicescu, Adela M. Ceau, Catalin Tiliscan, Vanda Roxana Nimigean, Viorica Tarmure, Alexandru G. Croitoru

A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects

Abstract:

Assessment of changes in total proteins level, serum and saliva IgG and IgA levels, serum IgM level, serum and saliva IgA/IgG ratio. The study was conducted on a group of 40 subjects, divided into 2 lots: the first lot consisting of 20 healthy individuals and the second consisting of 20 patients with hepatitis with hepatitis A virus (HAV). The levels of total proteins, serum and saliva IgG and IgA, serum IgM and serum and saliva IgA/IgG ratio have higher values in patients with hepatitis A, in comparison to healthy subjects, without necessarily exceeding the maximum admitted value. The results are significant from a statistical point of view. Due to the sensitivity and specificity of salivary anti-HAV IgM and IgG in patients with acute hepatitis A, compared with healthy subjects, there is a possibility of using salivary immunological tests instead of serum tests for the diagnosis and epidemiological study of HAV infection.

Keywords:
hepatitis A; immunoglobulins; total proteins; saliva; serum

Issue: 2018, Volume 69, Issue 5

Pages: 1125-1128

Publication date: 2018/6/15

https://doi.org/10.37358/RC.18.5.6273

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BALAN, D.G., SIANU, D.P., STANESCU, I.I., IONESCU, D., BALCANGIU, A.E.S., RADUCU, L., STOICESCU, S.M., CEAU, A.M., TILISCAN, C., NIMIGEAN, V.R., TARMURE, V., CROITORU, A.G., A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects, Rev. Chim., 69(5), 2018, 1125-1128.

Vancouver
Balan DG, Sianu DP, Stanescu II, Ionescu D, Balcangiu AES, Raducu L, Stoicescu SM, Ceau AM, Tiliscan C, Nimigean VR, Tarmure V, Croitoru AG. A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects. Rev. Chim.[internet]. 2018 May;69(5):1125-1128. Available from: https://doi.org/10.37358/RC.18.5.6273

APA 6th edition
Balan, D.G., Sianu, D.P., Stanescu, I.I., Ionescu, D., Balcangiu, A.E.S., Raducu, L.,... Croitoru, A.G. (2018). A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects. Revista de Chimie, 69(5), 1125-1128. https://doi.org/10.37358/RC.18.5.6273

Harvard
Balan, D.G., Sianu, D.P., Stanescu, I.I., Ionescu, D., Balcangiu, A.E.S., Raducu, L., Stoicescu, S.M., Ceau, A.M., Tiliscan, C., Nimigean, V.R., Tarmure, V., Croitoru, A.G. (2018). 'A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects', Revista de Chimie, 69(5), pp. 1125-1128. https://doi.org/10.37358/RC.18.5.6273

IEEE
D.G. Balan, D.P. Sianu, I.I. Stanescu, D. Ionescu, A.E.S. Balcangiu, L. Raducu, S.M. Stoicescu, A.M. Ceau, C. Tiliscan, V.R. Nimigean, V. Tarmure, A.G. Croitoru, "A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects". Revista de Chimie, vol. 69, no. 5, pp. 1125-1128, 2018. [online]. https://doi.org/10.37358/RC.18.5.6273

Text
Daniela G. Balan, Dan Piperea Sianu, Iulia I. Stanescu, Dorin Ionescu, Andra Elena Stroescu Balcangiu, Laura Raducu, Silvia Maria Stoicescu, Adela M. Ceau, Catalin Tiliscan, Vanda Roxana Nimigean, Viorica Tarmure, Alexandru G. Croitoru,
A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects,
Revista de Chimie,
Volume 69, Issue 5,
2018,
Pages 1125-1128,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.5.6273.
(https://revistadechimie.ro/Articles.asp?ID=6273)
Keywords: hepatitis A; immunoglobulins; total proteins; saliva; serum

RIS
TY - JOUR
T1 - A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects
A1 - Balan, Daniela G.
A2 - Sianu, Dan Piperea
A3 - Stanescu, Iulia I.
A4 - Ionescu, Dorin
A5 - Balcangiu, Andra Elena Stroescu
A6 - Raducu, Laura
A7 - Stoicescu, Silvia Maria
A8 - Ceau, Adela M.
A9 - Tiliscan, Catalin
A10 - Nimigean, Vanda Roxana
A11 - Tarmure, Viorica
A12 - Croitoru, Alexandru G.
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 5
SP - 1125
EP - 1128
UR - https://doi.org/10.37358/RC.18.5.6273
KW - hepatitis A
KW - immunoglobulins
KW - total proteins
KW - saliva
KW - serum
ER -

BibTex
@article{RevCh2018P1125,
author = {Balan Daniela G. and Sianu Dan Piperea and Stanescu Iulia I. and Ionescu Dorin and Balcangiu Andra Elena Stroescu and Raducu Laura and Stoicescu Silvia Maria and Ceau Adela M. and Tiliscan Catalin and Nimigean Vanda Roxana and Tarmure Viorica and Croitoru Alexandru G.},
title = {A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects},
journal = {Revista de Chimie},
volume = {69},
number = {5},
pages = {1125-1128},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.5.6273},
url = {https://revistadechimie.ro/Articles.asp?ID=6273}
}

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