Corneliu Tanase, Sanda Cosarca, Felicia Toma, Anca Mare, Adina Cosarca, Adrian Man, Amalia Miklos, Silvia Imre
Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens
Abstract:
Spruce is a used material in the wood industry and bark is regarded as a by-product. The aim of this study was to provide information about natural bioactive compounds from spruce (Picea abies L.) bark with potential therapeutic applications such as antibacterial activity against human pathogens. Spruce bark extract was obtained by the conventional aqueous extraction (EAM), and second with ultrasounds (USM). It was determined the total polyphenols by spectrophotometric methods and individual polyphenols by high-performance liquid chromatography (HPLC). For the determination of minimum inhibitory concentration was used microdilution technique. The following strains were tested: Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The yield of extracted polyphenols in the case of spruce bark extract was of 33.8mg gallic acid/gfor EAM and 28.73 mg gallic acid/g for USM. The compounds identified in samples, by HPLC, were vanillic acid and taxifolin.It was found that both extracts have antibacterial capacity for all bacteria tested. The antibacterial effect of both extracts was stronger against Gram positive cocci compared with Gram negative bacilli.Antimicrobial spectra and activities of the fractions and pure isolated compounds from the spruce bark, can be suggested the use of spruce bark in pharmaceutical preparations and as well as a food preservative.
Keywords: antimicrobial; spruce bark; green biotechnology; biorefinery; polyphenols
Cite this article as: TANASE, C., COSARCA, S., TOMA, F., MARE, A., COSARCA, A., MAN, A., MIKLOS, A., IMRE, S., Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens, Rev. Chim., 69(6), 2018, 1462-1467.
Vancouver Tanase C, Cosarca S, Toma F, Mare A, Cosarca A, Man A, Miklos A, Imre S. Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens. Rev. Chim.[internet]. 2018 Jun;69(6):1462-1467. Available from: https://doi.org/10.37358/RC.18.6.6347
APA 6th edition Tanase, C., Cosarca, S., Toma, F., Mare, A., Cosarca, A., Man, A., Miklos, A. & Imre, S. (2018). Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens. Revista de Chimie, 69(6), 1462-1467. https://doi.org/10.37358/RC.18.6.6347
Harvard Tanase, C., Cosarca, S., Toma, F., Mare, A., Cosarca, A., Man, A., Miklos, A., Imre, S. (2018). 'Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens', Revista de Chimie, 69(6), pp. 1462-1467. https://doi.org/10.37358/RC.18.6.6347
IEEE C. Tanase, S. Cosarca, F. Toma, A. Mare, A. Cosarca, A. Man, A. Miklos, S. Imre, "Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens". Revista de Chimie, vol. 69, no. 6, pp. 1462-1467, 2018. [online]. https://doi.org/10.37358/RC.18.6.6347
Text Corneliu Tanase, Sanda Cosarca, Felicia Toma, Anca Mare, Adina Cosarca, Adrian Man, Amalia Miklos, Silvia Imre, Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens, Revista de Chimie, Volume 69, Issue 6, 2018, Pages 1462-1467, ISSN 2668-8212, https://doi.org/10.37358/RC.18.6.6347. (https://revistadechimie.ro/Articles.asp?ID=6347) Keywords: antimicrobial; spruce bark; green biotechnology; biorefinery; polyphenols
RIS TY - JOUR T1 - Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens A1 - Tanase, Corneliu A2 - Cosarca, Sanda A3 - Toma, Felicia A4 - Mare, Anca A5 - Cosarca, Adina A6 - Man, Adrian A7 - Miklos, Amalia A8 - Imre, Silvia JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2018 VL - 69 IS - 6 SP - 1462 EP - 1467 UR - https://doi.org/10.37358/RC.18.6.6347 KW - antimicrobial KW - spruce bark KW - green biotechnology KW - biorefinery KW - polyphenols ER -
BibTex @article{RevCh2018P1462, author = {Tanase Corneliu and Cosarca Sanda and Toma Felicia and Mare Anca and Cosarca Adina and Man Adrian and Miklos Amalia and Imre Silvia}, title = {Antibacterial Activities of Spruce Bark (Picea abies L.) Extract and Its Components Against Human Pathogens}, journal = {Revista de Chimie}, volume = {69}, number = {6}, pages = {1462-1467}, year = {2018}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.18.6.6347}, url = {https://revistadechimie.ro/Articles.asp?ID=6347} }
