Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting

Namat, Razan Al; Felea, Maura Gabriela; Costache, Irina Iuliana; Aursulesei, Viviana; Petris, Antoniu; Mitu, Ovidiu; Constantin, Mihai; Sorodoc, Victorita; Sorodoc, Laurentiu; Miftode, Ionela Larisa; Miftode, Radu; Namat, Nadia Al; Namat, Dina Al; Luta, Andreea; Ion, Adriana; Mihalcia, Mirela Mihaela; Ciocoiu, Manuela; Tinica, Grigore; Mitu, Florin

Razan Al Namat, Maura Gabriela Felea, Irina Iuliana Costache, Viviana Aursulesei, Antoniu Petris, Ovidiu Mitu, Mihai Constantin, Victorita Sorodoc, Laurentiu Sorodoc, Ionela Larisa Miftode, Radu Miftode, Nadia Al Namat, Dina Al Namat, Andreea Luta, Adriana Ion, Mirela Mihaela Mihalcia, Manuela Ciocoiu, Grigore Tinica, Florin Mitu

Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting

Abstract:

Heart-type fatty acid-binding protein (H-FABP) is a non-invasive bio-marker, with high sensitivity and specificity, being capable to point out the myocardial injury and to predict major adverse cardiovascular events (MACE). Cardiac rehabilitation program, through a complex and sustained post-interventional management plays an important role in reducing the plasma levels of H-FABP. In the study, which included 120 post-coronary artery bypass (CABG) patients, we analyzed the link between low levels of general post-surgical health status and the presence of cardiovascular risk factors, common biochemical markers, and especially the role played by diabetic status in lowering the plasma H-FABP levels. From the group, 65 patients had been diagnosed with type 2 Diabetes Mellitus (T2DM). The H-FABP values decreased both in diabetics and in non-diabetics between the two phases of CR, 6 months away from CABG. More than half of the patients had important reduction of H-FABP, at 6 months after the onset of CR program. Half of the group registered a smaller reduction of H-FABP, but more noticeable in diabetics. Ischemic lesion during open heart surgery is linked to high levels of H-FABP and with an occurence risk of postoperative atrial fibrillation, that can be also triggered and sustained by multiple endocrine conditions related to aging. Thus, metabolic control should always remain a target of the complex management in cardiac rehabilitation.

Keywords:
heart-type fatty acid binding protein; coronary-artery bypass graft; cardiac rehabilitation; type 2 diabetes mellitus

Issue: 2018, Volume 69, Issue 10

Pages: 2712-2717

Publication date: 2018/11/15

https://doi.org/10.37358/RC.18.10.6608

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
NAMAT, R.A., FELEA, M.G., COSTACHE, I.I., AURSULESEI, V., PETRIS, A., MITU, O., CONSTANTIN, M., SORODOC, V., SORODOC, L., MIFTODE, I.L., MIFTODE, R., NAMAT, N.A., NAMAT, D.A., LUTA, A., ION, A., MIHALCIA, M.M., CIOCOIU, M., TINICA, G., MITU, F., Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting, Rev. Chim., 69(10), 2018, 2712-2717.

Vancouver
Namat RA, Felea MG, Costache II, Aursulesei V, Petris A, Mitu O, Constantin M, Sorodoc V, Sorodoc L, Miftode IL, Miftode R, Namat NA, Namat DA, Luta A, Ion A, Mihalcia MM, Ciocoiu M, Tinica G, Mitu F. Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting. Rev. Chim.[internet]. 2018 Oct;69(10):2712-2717. Available from: https://doi.org/10.37358/RC.18.10.6608

APA 6th edition
Namat, R.A., Felea, M.G., Costache, I.I., Aursulesei, V., Petris, A., Mitu, O.,... Mitu, F. (2018). Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting. Revista de Chimie, 69(10), 2712-2717. https://doi.org/10.37358/RC.18.10.6608

Harvard
Namat, R.A., Felea, M.G., Costache, I.I., Aursulesei, V., Petris, A., Mitu, O., Constantin, M., Sorodoc, V., Sorodoc, L., Miftode, I.L., Miftode, R., Namat, N.A., Namat, D.A., Luta, A., Ion, A., Mihalcia, M.M., Ciocoiu, M., Tinica, G., Mitu, F. (2018). 'Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting', Revista de Chimie, 69(10), pp. 2712-2717. https://doi.org/10.37358/RC.18.10.6608

IEEE
R.A. Namat, M.G. Felea, I.I. Costache, V. Aursulesei, A. Petris, O. Mitu, M. Constantin, V. Sorodoc, L. Sorodoc, I.L. Miftode, R. Miftode, N.A. Namat, D.A. Namat, A. Luta, A. Ion, M.M. Mihalcia, M. Ciocoiu, G. Tinica, F. Mitu, "Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting". Revista de Chimie, vol. 69, no. 10, pp. 2712-2717, 2018. [online]. https://doi.org/10.37358/RC.18.10.6608

Text
Razan Al Namat, Maura Gabriela Felea, Irina Iuliana Costache, Viviana Aursulesei, Antoniu Petris, Ovidiu Mitu, Mihai Constantin, Victorita Sorodoc, Laurentiu Sorodoc, Ionela Larisa Miftode, Radu Miftode, Nadia Al Namat, Dina Al Namat, Andreea Luta, Adriana Ion, Mirela Mihaela Mihalcia, Manuela Ciocoiu, Grigore Tinica, Florin Mitu,
Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2712-2717,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6608.
(https://revistadechimie.ro/Articles.asp?ID=6608)
Keywords: heart-type fatty acid binding protein; coronary-artery bypass graft; cardiac rehabilitation; type 2 diabetes mellitus

RIS
TY - JOUR
T1 - Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting
A1 - Namat, Razan Al
A2 - Felea, Maura Gabriela
A3 - Costache, Irina Iuliana
A4 - Aursulesei, Viviana
A5 - Petris, Antoniu
A6 - Mitu, Ovidiu
A7 - Constantin, Mihai
A8 - Sorodoc, Victorita
A9 - Sorodoc, Laurentiu
A10 - Miftode, Ionela Larisa
A11 - Miftode, Radu
A12 - Namat, Nadia Al
A13 - Namat, Dina Al
A14 - Luta, Andreea
A15 - Ion, Adriana
A16 - Mihalcia, Mirela Mihaela
A17 - Ciocoiu, Manuela
A18 - Tinica, Grigore
A19 - Mitu, Florin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2712
EP - 2717
UR - https://doi.org/10.37358/RC.18.10.6608
KW - heart-type fatty acid binding protein
KW - coronary-artery bypass graft
KW - cardiac rehabilitation
KW - type 2 diabetes mellitus
ER -

BibTex
@article{RevCh2018P2712,
author = {Namat Razan Al and Felea Maura Gabriela and Costache Irina Iuliana and Aursulesei Viviana and Petris Antoniu and Mitu Ovidiu and Constantin Mihai and Sorodoc Victorita and Sorodoc Laurentiu and Miftode Ionela Larisa and Miftode Radu and Namat Nadia Al and Namat Dina Al and Luta Andreea and Ion Adriana and Mihalcia Mirela Mihaela and Ciocoiu Manuela and Tinica Grigore and Mitu Florin},
title = {Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2712-2717},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6608},
url = {https://revistadechimie.ro/Articles.asp?ID=6608}
}

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