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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 10, 2740-2743

https://doi.org/10.37358/RC.18.10.6616

Corina Grigoriu, Florentina Furtunescu, Laura Elena Gaman, Alice Lavinia Balaceanu, Ramona Buzatu, Mihai Grigoriu

A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy

Abstract:

Changes in lipid metabolism from pregnancies with preeclampsia (PE) are a challenge for the obstetrician, because they contribute to the pathological chain and to some specific severe complications (severe hypertriglyceridemia of pregnancy, acute pancreatitis etc). Patients at risk for PE have higher levels of triglycerides, total and LDL cholesterol, compared to normotensive pregnant women. We searched the link between lipidic changes in pregnancies with PE and the way secondary prophylactic treatments with acetylsalicilic acid or low molecular weight heparin (LMWH) can influence the evolution of pregnancy, avoiding the severe complications of this disease. We identified patients at risk of developing PE and then applied a secondary prophylaxis with either a platelet antiaggregant (acetylsalycilic acid - a group of 36 patients) or an anticoagulant prophylaxis with LMWH - enoxaparin (a second group of 37 patients), aiming a decrease of severe complications of PIH/PE. The control group consisted of 33 pregnant women with risk factors for PE, without any secondary prophylaxis, according to actual guidelines. We periodically determined (at 14, 16-20 and 34 weeks of pregnancy) several biochemical parameters: triglycerides, uric acid, free fatty acids, total cholesterol and albuminemia. In the present paper we present the evolution of triglyceridemia in the studied groups, considering hypertriglyceridemia as an important prognostic factor for maternal complications in pregnancy. The most important result of our study is the statistically significant extremely low rate of complications in the treatment groups.
Keywords:
preeclampsia; hypertriglyceridemia; acetylsalycilic acid; LMWH

Issue: 2018, Volume 69, Issue 10
Pages: 2740-2743
Publication date: 2018/11/15
https://doi.org/10.37358/RC.18.10.6616
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GRIGORIU, C., FURTUNESCU, F., GAMAN, L.E., BALACEANU, A.L., BUZATU, R., GRIGORIU, M., A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy, Rev. Chim., 69(10), 2018, 2740-2743.

Vancouver
Grigoriu C, Furtunescu F, Gaman LE, Balaceanu AL, Buzatu R, Grigoriu M. A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy. Rev. Chim.[internet]. 2018 Oct;69(10):2740-2743. Available from: https://doi.org/10.37358/RC.18.10.6616


APA 6th edition
Grigoriu, C., Furtunescu, F., Gaman, L.E., Balaceanu, A.L., Buzatu, R. & Grigoriu, M. (2018). A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy. Revista de Chimie, 69(10), 2740-2743. https://doi.org/10.37358/RC.18.10.6616


Harvard
Grigoriu, C., Furtunescu, F., Gaman, L.E., Balaceanu, A.L., Buzatu, R., Grigoriu, M. (2018). 'A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy', Revista de Chimie, 69(10), pp. 2740-2743. https://doi.org/10.37358/RC.18.10.6616


IEEE
C. Grigoriu, F. Furtunescu, L.E. Gaman, A.L. Balaceanu, R. Buzatu, M. Grigoriu, "A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy". Revista de Chimie, vol. 69, no. 10, pp. 2740-2743, 2018. [online]. https://doi.org/10.37358/RC.18.10.6616


Text
Corina Grigoriu, Florentina Furtunescu, Laura Elena Gaman, Alice Lavinia Balaceanu, Ramona Buzatu, Mihai Grigoriu,
A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2740-2743,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6616.
(https://revistadechimie.ro/Articles.asp?ID=6616)
Keywords: preeclampsia; hypertriglyceridemia; acetylsalycilic acid; LMWH


RIS
TY - JOUR
T1 - A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy
A1 - Grigoriu, Corina
A2 - Furtunescu, Florentina
A3 - Gaman, Laura Elena
A4 - Balaceanu, Alice Lavinia
A5 - Buzatu, Ramona
A6 - Grigoriu, Mihai
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2740
EP - 2743
UR - https://doi.org/10.37358/RC.18.10.6616
KW - preeclampsia
KW - hypertriglyceridemia
KW - acetylsalycilic acid
KW - LMWH
ER -


BibTex
@article{RevCh2018P2740,
author = {Grigoriu Corina and Furtunescu Florentina and Gaman Laura Elena and Balaceanu Alice Lavinia and Buzatu Ramona and Grigoriu Mihai},
title = {A Biochemical Marker of Preeclampsia - Hypertriglyceridemia - and the Impact of Secondary Prevention Therapy},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2740-2743},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6616},
url = {https://revistadechimie.ro/Articles.asp?ID=6616}
}
 
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