Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas

Cucu, Andrei Ionut; Turliuc, Mihaela Dana; Carauleanu, Alexandru; Poeata, Ion; Costea, Claudia Florida; Dumitrescu, Gabriela Florenta; Sava, Anca

Andrei Ionut Cucu, Mihaela Dana Turliuc, Alexandru Carauleanu, Ion Poeata, Claudia Florida Costea, Gabriela Florenta Dumitrescu, Anca Sava

Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas

Abstract:

Aim of this study was to perform a retrospective evaluation of the radiological, clinical and pathological features influencing the occurrence of peritumoral brain edema (PBE) and understanding the responsible chemical mediators involved. We have examined magnetic resonance imaging(MRI), symptoms and pathology for 25 patients with convexity atypical meningiomas (WHO grade II), who underwent surgery at Professor Dr. N. Oblu Emergency Clinical Hospital between 2010 and 2017. We evaluated the possible prognostic factors related to peritumoral edema including: demography (age, gender), pathology (anatomical localization of the tumor, tumor volume, brain invasion, shape of tumor margin), symptoms and neuroimaging characteristics such as high signal intensity of the tumor on T2-weighted images (T2WI), contrast enhancement and heterogeneity. Age, gender, anatomical location of the tumor and brain invasion were not correlated with peritumoral edema. Also, the neuroimaging characteristics (homogeneity, high signal intensity on T2WI, high contrast enhancement) or the presence of motor deficit were not statistically significant regarding the relationship with the edema. Peritumoral edema and irregular tumor margins were statistically significantly (p=0.03). Tumor volume was not associated with the peritumoral edema. We also found other significant statistical correlations of the radiological features, which are worth mentioning: high-contrast enhancement with the age of the patient (p=0.006), high signal intensity on T2WI with tumor volume (p=0.03) and tumor heterogeneity with irregular tumor margins (p=0.002). The results of this study demonstrate that an irregular tumor margin may be an important predictive factor that would influence the occurrence of peritumoral edema in atypical meningiomas.

Keywords:
peritumoral brain edema; atypical meningiomas; convexity meningiomas; MRI characteristics; cerebrospinal fluid

Issue: 2018, Volume 69, Issue 10

Pages: 2804-2807

Publication date: 2018/11/15

https://doi.org/10.37358/RC.18.10.6628

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CUCU, A.I., TURLIUC, M.D., CARAULEANU, A., POEATA, I., COSTEA, C.F., DUMITRESCU, G.F., SAVA, A., Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas, Rev. Chim., 69(10), 2018, 2804-2807.

Vancouver
Cucu AI, Turliuc MD, Carauleanu A, Poeata I, Costea CF, Dumitrescu GF, Sava A. Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas. Rev. Chim.[internet]. 2018 Oct;69(10):2804-2807. Available from: https://doi.org/10.37358/RC.18.10.6628

APA 6th edition
Cucu, A.I., Turliuc, M.D., Carauleanu, A., Poeata, I., Costea, C.F., Dumitrescu, G.F. & Sava, A. (2018). Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas. Revista de Chimie, 69(10), 2804-2807. https://doi.org/10.37358/RC.18.10.6628

Harvard
Cucu, A.I., Turliuc, M.D., Carauleanu, A., Poeata, I., Costea, C.F., Dumitrescu, G.F., Sava, A. (2018). 'Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas', Revista de Chimie, 69(10), pp. 2804-2807. https://doi.org/10.37358/RC.18.10.6628

IEEE
A.I. Cucu, M.D. Turliuc, A. Carauleanu, I. Poeata, C.F. Costea, G.F. Dumitrescu, A. Sava, "Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas". Revista de Chimie, vol. 69, no. 10, pp. 2804-2807, 2018. [online]. https://doi.org/10.37358/RC.18.10.6628

Text
Andrei Ionut Cucu, Mihaela Dana Turliuc, Alexandru Carauleanu, Ion Poeata, Claudia Florida Costea, Gabriela Florenta Dumitrescu, Anca Sava,
Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2804-2807,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6628.
(https://revistadechimie.ro/Articles.asp?ID=6628)
Keywords: peritumoral brain edema; atypical meningiomas; convexity meningiomas; MRI characteristics; cerebrospinal fluid

RIS
TY - JOUR
T1 - Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas
A1 - Cucu, Andrei Ionut
A2 - Turliuc, Mihaela Dana
A3 - Carauleanu, Alexandru
A4 - Poeata, Ion
A5 - Costea, Claudia Florida
A6 - Dumitrescu, Gabriela Florenta
A7 - Sava, Anca
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2804
EP - 2807
UR - https://doi.org/10.37358/RC.18.10.6628
KW - peritumoral brain edema
KW - atypical meningiomas
KW - convexity meningiomas
KW - MRI characteristics
KW - cerebrospinal fluid
ER -

BibTex
@article{RevCh2018P2804,
author = {Cucu Andrei Ionut and Turliuc Mihaela Dana and Carauleanu Alexandru and Poeata Ion and Costea Claudia Florida and Dumitrescu Gabriela Florenta and Sava Anca},
title = {Chemical Aspects of Peritumoral Cerebral Edema in Atypical Meningiomas},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2804-2807},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6628},
url = {https://revistadechimie.ro/Articles.asp?ID=6628}
}

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