ABOUT INDEXING BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER AUTHOR'S PAGE NEWS, EVENTS CONTACT
REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

REVISTA DE CHIMIE Latest Issue

LATEST ISSUE >>>

   Volume 75, 2024
   Volume 74, 2023
   Volume 73, 2022
   Volume 72, 2021
   Volume 71, 2020
   Volume 70, 2019
   Volume 69, 2018
   Volume 68, 2017
   Volume 67, 2016
   Volume 66, 2015
   Volume 65, 2014
   Volume 64, 2013
   Volume 63, 2012
   Volume 62, 2011
   Volume 61, 2010
   Volume 60, 2009
   Volume 59, 2008
   Volume 58, 2007
 
<<<< back

Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 10, 2916-2020

https://doi.org/10.37358/RC.18.10.6653

Monica Moraru, Carmen Lidia Chitescu, Aurel Nechita, Luana Andreea Macovei, Iuliu Fulga

LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine

Abstract:

In the present work, LC- Q ExactiveOrbitrap high resolution MS techique in both full-scan MS and targeted MS/MS modes was applied to identify psychoactive substances in human urine samples. Methylenedioxy-pyrovalerone (MDPV), methylenedioxy-alpha-pyrrolidino-butyrophenone(MDPBP) and the main metabolites of both compounds were identified. The preliminary full-scan screening was folowed by targeted ion fragmentation (t-MS2) enabling confirmatory analysis and mass spectral characterization. The presented case is the first confirmation of MDPBP abuse in Romania supported by the toxicological identification of the parent compound and the main metabolites in human urine.
Keywords:
designer drugs; MDPV; MDPBP; HR-MS

Issue: 2018, Volume 69, Issue 10
Pages: 2916-2020
Publication date: 2018/11/15
https://doi.org/10.37358/RC.18.10.6653
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
MORARU, M., CHITESCU, C.L., NECHITA, A., MACOVEI, L.A., FULGA, I., LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine, Rev. Chim., 69(10), 2018, 2916-2020.

Vancouver
Moraru M, Chitescu CL, Nechita A, Macovei LA, Fulga I. LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine. Rev. Chim.[internet]. 2018 Oct;69(10):2916-2020. Available from: https://doi.org/10.37358/RC.18.10.6653


APA 6th edition
Moraru, M., Chitescu, C.L., Nechita, A., Macovei, L.A. & Fulga, I. (2018). LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine. Revista de Chimie, 69(10), 2916-2020. https://doi.org/10.37358/RC.18.10.6653


Harvard
Moraru, M., Chitescu, C.L., Nechita, A., Macovei, L.A., Fulga, I. (2018). 'LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine', Revista de Chimie, 69(10), pp. 2916-2020. https://doi.org/10.37358/RC.18.10.6653


IEEE
M. Moraru, C.L. Chitescu, A. Nechita, L.A. Macovei, I. Fulga, "LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine". Revista de Chimie, vol. 69, no. 10, pp. 2916-2020, 2018. [online]. https://doi.org/10.37358/RC.18.10.6653


Text
Monica Moraru, Carmen Lidia Chitescu, Aurel Nechita, Luana Andreea Macovei, Iuliu Fulga,
LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2916-2020,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6653.
(https://revistadechimie.ro/Articles.asp?ID=6653)
Keywords: designer drugs; MDPV; MDPBP; HR-MS


RIS
TY - JOUR
T1 - LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine
A1 - Moraru, Monica
A2 - Chitescu, Carmen Lidia
A3 - Nechita, Aurel
A4 - Macovei, Luana Andreea
A5 - Fulga, Iuliu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2916
EP - 2020
UR - https://doi.org/10.37358/RC.18.10.6653
KW - designer drugs; MDPV; MDPBP; HR-MS
ER -


BibTex
@article{RevCh2018P2916,
author = {Moraru Monica and Chitescu Carmen Lidia and Nechita Aurel and Macovei Luana Andreea and Fulga Iuliu},
title = {LC-High-resolution MS Analysis of the Designer Drugs Methylenedioxy-Pyrovalerone (MDPV) and Methylenedioxy-alpha- pyrolidinobutyrophenone (MDPBP) and Their Main Metabolites in Human Urine},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2916-2020},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6653},
url = {https://revistadechimie.ro/Articles.asp?ID=6653}
}
 
<<<< back
 
PUBLISHING SECTION
Author Guidelines
 * Paper Drafting
 * Paper Template
 * Ethical Statement
 * Paper Submission
Ghidul Autorului (ro)
Submit Paper
Author's Page
Publishing Ethics
Peer Review Process
Open Access & Archiving Policy
 Search Authors
 LATEST NEWS
REvista de Chimie NUMAR OMAGIAL PETRU PONI.. detalii
REvista de Chimie Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
dictionar English-Romanian Dictionary for Mechanical Engineering
(download pdf)
  News, Events
Crossref Member Badge
 DOI  logo
 Gold Open Access | Source=http://www.plos.org/  | Author=art designer at PLoS
Creative Commons License
 Conferences of Contemporary
 Chemistry
 Biblioteca Chimiei
 Materiale Plastice