Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds

Pintilie, Lucia; Stefaniu, Amalia; Nicu, Alina Ioana; Negut, Catalina; Tanase, Constantin; Caproiu, Miron Teodor

Lucia Pintilie, Amalia Stefaniu, Alina Ioana Nicu, Catalina Negut, Constantin Tanase, Miron Teodor Caproiu

Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds

Abstract:

A series of oxazolidinone compounds have been obtained and characterized by physico-chemical methods and antimicrobial activity against Staphylococcus Aureus ATCC 6538. For the synthesized compounds have been performed calculations of characteristics and molecular properties, using Spartan 14 Software from Wavefunction, Inc. Irvine, CA. and molecular docking studies using CLC Drug Discovery Workbench 2.4 software, to identify and visualize the most likely interaction ligand (oxazolidinone derivatives) with the receptor protein.

Keywords:
linezolid; oxazolidinone; antimicrobial activity; molecular docking

Issue: 2018, Volume 69, Issue 11

Pages: 2981-2986

Publication date: 2018/12/15

https://doi.org/10.37358/RC.18.11.6666

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
PINTILIE, L., STEFANIU, A., NICU, A.I., NEGUT, C., TANASE, C., CAPROIU, M.T., Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds, Rev. Chim., 69(11), 2018, 2981-2986.

Vancouver
Pintilie L, Stefaniu A, Nicu AI, Negut C, Tanase C, Caproiu MT. Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds. Rev. Chim.[internet]. 2018 Nov;69(11):2981-2986. Available from: https://doi.org/10.37358/RC.18.11.6666

APA 6th edition
Pintilie, L., Stefaniu, A., Nicu, A.I., Negut, C., Tanase, C. & Caproiu, M.T. (2018). Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds. Revista de Chimie, 69(11), 2981-2986. https://doi.org/10.37358/RC.18.11.6666

Harvard
Pintilie, L., Stefaniu, A., Nicu, A.I., Negut, C., Tanase, C., Caproiu, M.T. (2018). 'Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds', Revista de Chimie, 69(11), pp. 2981-2986. https://doi.org/10.37358/RC.18.11.6666

IEEE
L. Pintilie, A. Stefaniu, A.I. Nicu, C. Negut, C. Tanase, M.T. Caproiu, "Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds". Revista de Chimie, vol. 69, no. 11, pp. 2981-2986, 2018. [online]. https://doi.org/10.37358/RC.18.11.6666

Text
Lucia Pintilie, Amalia Stefaniu, Alina Ioana Nicu, Catalina Negut, Constantin Tanase, Miron Teodor Caproiu,
Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds,
Revista de Chimie,
Volume 69, Issue 11,
2018,
Pages 2981-2986,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.11.6666.
(https://revistadechimie.ro/Articles.asp?ID=6666)
Keywords: linezolid; oxazolidinone; antimicrobial activity; molecular docking

RIS
TY - JOUR
T1 - Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds
A1 - Pintilie, Lucia
A2 - Stefaniu, Amalia
A3 - Nicu, Alina Ioana
A4 - Negut, Catalina
A5 - Tanase, Constantin
A6 - Caproiu, Miron Teodor
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 11
SP - 2981
EP - 2986
UR - https://doi.org/10.37358/RC.18.11.6666
KW - linezolid
KW - oxazolidinone
KW - antimicrobial activity
KW - molecular docking
ER -

BibTex
@article{RevCh2018P2981,
author = {Pintilie Lucia and Stefaniu Amalia and Nicu Alina Ioana and Negut Catalina and Tanase Constantin and Caproiu Miron Teodor},
title = {Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds},
journal = {Revista de Chimie},
volume = {69},
number = {11},
pages = {2981-2986},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.11.6666},
url = {https://revistadechimie.ro/Articles.asp?ID=6666}
}

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