The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients

Grosu, Cristina; Mastaleru, Alexandra; Costan, Victor Vlad; Nita, Otilia; Constantin, Maria Magdalena Leon

Cristina Grosu, Alexandra Mastaleru, Victor Vlad Costan, Otilia Nita, Maria Magdalena Leon Constantin

The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients

Abstract:

Cerebrovascular diseases have become a leading cause of mortality and major invalidity throughout the world in the last years. The levels of cholesterol and triglycerides are among the modifiable risk factors for stroke. The intima media thickness (IMT) is a very good marker for subclinical atherosclerosis and also for predicting future cardio- and cerebrovascular events. The aim of this study was to determine correlations between the lipid profile and the value of the intima media thickness as a risk factor for stroke in first degree relatives of stroke patients. We evaluated a total of 176 subjects, selected by well defined criteria, divided into three groups: stroke patients, first degree relatives of stroke patients and a healthy control group. We measured weight, height and body mass index, the levels of cholesterol and triglycerides, and IMT by cervical ultrasound mode B, at the common carotid artery (CCA) and internal carotid artery (ICA) bilaterally. The mean values of lipids were in the normal range. However, in the stroke group, both cholesterol and triglyceride levels were increased compared to the other groups. The triglycerides level positively correlated with IMT in the CCA in both control and stroke patients, but this was not the case for cholesterol levels. Also, the increase in IMT in stroke patients correlated with an increase in IMT of their relatives. Further research is needed in order to elaborate a screening algorithm for primary prevention of stroke in first degree relatives of stroke patients.

Keywords:
cholesterol; triglyceride; intima media thickness; stroke

Issue: 2018, Volume 69, Issue 11

Pages: 3068-3071

Publication date: 2018/12/15

https://doi.org/10.37358/RC.18.11.6684

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GROSU, C., MASTALERU, A., COSTAN, V.V., NITA, O., CONSTANTIN, M.M.L., The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients, Rev. Chim., 69(11), 2018, 3068-3071.

Vancouver
Grosu C, Mastaleru A, Costan VV, Nita O, Constantin MML. The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients. Rev. Chim.[internet]. 2018 Nov;69(11):3068-3071. Available from: https://doi.org/10.37358/RC.18.11.6684

APA 6th edition
Grosu, C., Mastaleru, A., Costan, V.V., Nita, O. & Constantin, M.M.L. (2018). The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients. Revista de Chimie, 69(11), 3068-3071. https://doi.org/10.37358/RC.18.11.6684

Harvard
Grosu, C., Mastaleru, A., Costan, V.V., Nita, O., Constantin, M.M.L. (2018). 'The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients', Revista de Chimie, 69(11), pp. 3068-3071. https://doi.org/10.37358/RC.18.11.6684

IEEE
C. Grosu, A. Mastaleru, V.V. Costan, O. Nita, M.M.L. Constantin, "The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients". Revista de Chimie, vol. 69, no. 11, pp. 3068-3071, 2018. [online]. https://doi.org/10.37358/RC.18.11.6684

Text
Cristina Grosu, Alexandra Mastaleru, Victor Vlad Costan, Otilia Nita, Maria Magdalena Leon Constantin,
The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients,
Revista de Chimie,
Volume 69, Issue 11,
2018,
Pages 3068-3071,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.11.6684.
(https://revistadechimie.ro/Articles.asp?ID=6684)
Keywords: cholesterol; triglyceride; intima media thickness; stroke

RIS
TY - JOUR
T1 - The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients
A1 - Grosu, Cristina
A2 - Mastaleru, Alexandra
A3 - Costan, Victor Vlad
A4 - Nita, Otilia
A5 - Constantin, Maria Magdalena Leon
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 11
SP - 3068
EP - 3071
UR - https://doi.org/10.37358/RC.18.11.6684
KW - cholesterol
KW - triglyceride
KW - intima media thickness
KW - stroke
ER -

BibTex
@article{RevCh2018P3068,
author = {Grosu Cristina and Mastaleru Alexandra and Costan Victor Vlad and Nita Otilia and Constantin Maria Magdalena Leon},
title = {The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients},
journal = {Revista de Chimie},
volume = {69},
number = {11},
pages = {3068-3071},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.11.6684},
url = {https://revistadechimie.ro/Articles.asp?ID=6684}
}

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