Gabriela Dumitru, Sara Abidar, Mohamad Nhiri, Lucian Hritcu, Razvan Stefan Boiangiu, Ion Sandu, Elena Todirascu-Ciornea
Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model
Abstract:
The richness in soluble sugars and polyphenols, especially condensed tannins, vitamins, minerals and other phytochemicals, recommends Ceratonia siliqua L. species for use in therapeutic practice, especially in terms of neurotoxicity - a major public health problem. Neurodegenerative disorders arise from various metabolic dysfunctions or from the administration of chemicals such as 6-hydroxydopamine (6-OHDA), a catecholaminergic neurotoxin that induces oxidative stress and, implicitly, cellular apoptosis. The results obtained after the administration of the methanolic extract of carob in Danio rerio highlights a phenomenon of prevention of short-term memory deficits, as well as a significant antioxidant activity.
Cite this article as: DUMITRU, G., ABIDAR, S., NHIRI, M., HRITCU, L., BOIANGIU, R.S., SANDU, I., TODIRASCU-CIORNEA, E., Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model, Rev. Chim., 69(12), 2018, 3545-3548.
Vancouver Dumitru G, Abidar S, Nhiri M, Hritcu L, Boiangiu RS, Sandu I, Todirascu-Ciornea E. Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model. Rev. Chim.[internet]. 2018 Dec;69(12):3545-3548. Available from: https://doi.org/10.37358/RC.18.12.6788
APA 6th edition Dumitru, G., Abidar, S., Nhiri, M., Hritcu, L., Boiangiu, R.S., Sandu, I. & Todirascu-Ciornea, E. (2018). Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model. Revista de Chimie, 69(12), 3545-3548. https://doi.org/10.37358/RC.18.12.6788
Harvard Dumitru, G., Abidar, S., Nhiri, M., Hritcu, L., Boiangiu, R.S., Sandu, I., Todirascu-Ciornea, E. (2018). 'Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model', Revista de Chimie, 69(12), pp. 3545-3548. https://doi.org/10.37358/RC.18.12.6788
IEEE G. Dumitru, S. Abidar, M. Nhiri, L. Hritcu, R.S. Boiangiu, I. Sandu, E. Todirascu-Ciornea, "Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model". Revista de Chimie, vol. 69, no. 12, pp. 3545-3548, 2018. [online]. https://doi.org/10.37358/RC.18.12.6788
Text Gabriela Dumitru, Sara Abidar, Mohamad Nhiri, Lucian Hritcu, Razvan Stefan Boiangiu, Ion Sandu, Elena Todirascu-Ciornea, Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model, Revista de Chimie, Volume 69, Issue 12, 2018, Pages 3545-3548, ISSN 2668-8212, https://doi.org/10.37358/RC.18.12.6788. (https://revistadechimie.ro/Articles.asp?ID=6788) Keywords: 6-OHDA; carob; Danio rerio; memory; oxidative stress
RIS TY - JOUR T1 - Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model A1 - Dumitru, Gabriela A2 - Abidar, Sara A3 - Nhiri, Mohamad A4 - Hritcu, Lucian A5 - Boiangiu, Razvan Stefan A6 - Sandu, Ion A7 - Todirascu-Ciornea, Elena JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2018 VL - 69 IS - 12 SP - 3545 EP - 3548 UR - https://doi.org/10.37358/RC.18.12.6788 KW - 6-OHDA KW - carob KW - Danio rerio KW - memory KW - oxidative stress ER -
BibTex @article{RevCh2018P3545, author = {Dumitru Gabriela and Abidar Sara and Nhiri Mohamad and Hritcu Lucian and Boiangiu Razvan Stefan and Sandu Ion and Todirascu-Ciornea Elena}, title = {Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model}, journal = {Revista de Chimie}, volume = {69}, number = {12}, pages = {3545-3548}, year = {2018}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.18.12.6788}, url = {https://revistadechimie.ro/Articles.asp?ID=6788} }
