Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization

Cavalu, Simona; Bisboaca, Simona; Mates, Ileana Mariana; Pasca, Paula Melania; Laslo, Vasile; Costea, Traian; Fritea, Luminita; Vicas, Simona

Simona Cavalu, Simona Bisboaca, Ileana Mariana Mates, Paula Melania Pasca, Vasile Laslo, Traian Costea, Luminita Fritea, Simona Vicas

Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization

Abstract:

The aim of our study was to prepare and characterize chitosan-based nanoparticles encapsulating propolis extract by ionotropic gelation and glutaraldehyde cross-linking technique. Both spectroscopic (UV-Vis, FTIR) and microscopic techniques (AFM) were applied for structural characterization of nanoparticles, along with entrapment and release study of propolis extract. The physico-chemical properties and morphological features of the obtained nanoparticles demonstrated a good correlation between all the investigated methods. Moreover, the bioactive compounds were stable upon the encapsulation procedure. Propolis release from the polymeric matrix was monitored in both simulated gastric acid and simulated intestinal fluids, concluding that our proposed formulation is suitable for controlled release. These results may provide a novel design, with improved bioavailability, stability and nutritional value of propolis bioactive compounds during processing and storage, with possible applications in food and nutraceutical industries.

Keywords:
propolis; nanoparticles; chitosan; Arabic gum; DLS; AFM; FTIR

Issue: 2018, Volume 69, Issue 12

Pages: 3756-3760

Publication date: 2019/1/15

https://doi.org/10.37358/RC.18.12.6836

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CAVALU, S., BISBOACA, S., MATES, I.M., PASCA, P.M., LASLO, V., COSTEA, T., FRITEA, L., VICAS, S., Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization, Rev. Chim., 69(12), 2018, 3756-3760.

Vancouver
Cavalu S, Bisboaca S, Mates IM, Pasca PM, Laslo V, Costea T, Fritea L, Vicas S. Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization. Rev. Chim.[internet]. 2018 Dec;69(12):3756-3760. Available from: https://doi.org/10.37358/RC.18.12.6836

APA 6th edition
Cavalu, S., Bisboaca, S., Mates, I.M., Pasca, P.M., Laslo, V., Costea, T., Fritea, L. & Vicas, S. (2018). Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization. Revista de Chimie, 69(12), 3756-3760. https://doi.org/10.37358/RC.18.12.6836

Harvard
Cavalu, S., Bisboaca, S., Mates, I.M., Pasca, P.M., Laslo, V., Costea, T., Fritea, L., Vicas, S. (2018). 'Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization', Revista de Chimie, 69(12), pp. 3756-3760. https://doi.org/10.37358/RC.18.12.6836

IEEE
S. Cavalu, S. Bisboaca, I.M. Mates, P.M. Pasca, V. Laslo, T. Costea, L. Fritea, S. Vicas, "Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization". Revista de Chimie, vol. 69, no. 12, pp. 3756-3760, 2018. [online]. https://doi.org/10.37358/RC.18.12.6836

Text
Simona Cavalu, Simona Bisboaca, Ileana Mariana Mates, Paula Melania Pasca, Vasile Laslo, Traian Costea, Luminita Fritea, Simona Vicas,
Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization,
Revista de Chimie,
Volume 69, Issue 12,
2018,
Pages 3756-3760,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.12.6836.
(https://revistadechimie.ro/Articles.asp?ID=6836)
Keywords: propolis; nanoparticles; chitosan; Arabic gum; DLS; AFM; FTIR

RIS
TY - JOUR
T1 - Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization
A1 - Cavalu, Simona
A2 - Bisboaca, Simona
A3 - Mates, Ileana Mariana
A4 - Pasca, Paula Melania
A5 - Laslo, Vasile
A6 - Costea, Traian
A7 - Fritea, Luminita
A8 - Vicas, Simona
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 12
SP - 3756
EP - 3760
UR - https://doi.org/10.37358/RC.18.12.6836
KW - propolis
KW - nanoparticles
KW - chitosan
KW - Arabic gum
KW - DLS
KW - AFM
KW - FTIR
ER -

BibTex
@article{RevCh2018P3756,
author = {Cavalu Simona and Bisboaca Simona and Mates Ileana Mariana and Pasca Paula Melania and Laslo Vasile and Costea Traian and Fritea Luminita and Vicas Simona},
title = {Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization},
journal = {Revista de Chimie},
volume = {69},
number = {12},
pages = {3756-3760},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.12.6836},
url = {https://revistadechimie.ro/Articles.asp?ID=6836}
}

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