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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 1, 69-73

https://doi.org/10.37358/RC.19.1.6853

Adela Viviana Sitar Taut, Olga Orasan, Adriana Fodor, Anca Daniela Farcas, Simina Tarmure Sarlea, Gabriela Dogaru, Dumitru Tudor Zdrenghea, Dana Pop, Angela Cozma

The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?

Abstract:

Were investigated the relationship between gender, cardiovascular risk factors and inflammation in metabolic syndrome (MetS) patients. 100 consecutive patients (75 women), 73 with MetS, mean age 57.52±9.77 years, were examined. Adhesion molecules (sICAM1, sVCAM1) were measured in the stored serum samples collected using the ELISA method. The classification of MetS was based on IDF guidelines. The study was carried out at the Department of Cardiology, Clinical Rehabilitation Hospital, Cluj-Napoca, Romania. MetS patients presented lower sICAM1 values (225.01±86.75 ng/mL vs 234.22±82.23 ng/mL, p=NS), but higher sVCAM1 values (605.34±298.69 ng/mL vs 552.29±233.77 ng/mL, p=NS). Differences between patients with vs without metabolic syndrome were found only in men for sICAM1 (194.73±37.92 ng/mL vs 282±27.15 ng/mL, p[0.001). Considering the HOMA index, a significant difference for sICAM1 was found in men (patients within the upper quartile vs the lower quartile, p=0.002), but also between women and men within the upper quartile of HOMA (for sICAM1 p=0.038). No significant differences were found for sVCAM1. In the case of males, sICAM1 was an independent predictor of metabolic syndrome, with a very good capacity to identify metabolic syndrome (AUROC=0.987, p=0.0001, Se=89.47%, Sp=100%). In conclusion, just in men, sICAM1 seems to have an excellent capacity to differentiate between MetS+ and MetS- patients, to predict MetS development.
Keywords:
adhesion molecule; gender; IDF; inflammation; metabolic syndrome

Issue: 2019, Volume 70, Issue 1
Pages: 69-73
Publication date: 2019/2/15
https://doi.org/10.37358/RC.19.1.6853
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
TAUT, A.V.S., ORASAN, O., FODOR, A., FARCAS, A.D., SARLEA, S.T., DOGARU, G., ZDRENGHEA, D.T., POP, D., COZMA, A., The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?, Rev. Chim., 70(1), 2019, 69-73.

Vancouver
Taut AVS, Orasan O, Fodor A, Farcas AD, Sarlea ST, Dogaru G, Zdrenghea DT, Pop D, Cozma A. The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?. Rev. Chim.[internet]. 2019 Jan;70(1):69-73. Available from: https://doi.org/10.37358/RC.19.1.6853


APA 6th edition
Taut, A.V.S., Orasan, O., Fodor, A., Farcas, A.D., Sarlea, S.T., Dogaru, G.,... Cozma, A. (2019). The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?. Revista de Chimie, 70(1), 69-73. https://doi.org/10.37358/RC.19.1.6853


Harvard
Taut, A.V.S., Orasan, O., Fodor, A., Farcas, A.D., Sarlea, S.T., Dogaru, G., Zdrenghea, D.T., Pop, D., Cozma, A. (2019). 'The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?', Revista de Chimie, 70(1), pp. 69-73. https://doi.org/10.37358/RC.19.1.6853


IEEE
A.V.S. Taut, O. Orasan, A. Fodor, A.D. Farcas, S.T. Sarlea, G. Dogaru, D.T. Zdrenghea, D. Pop, A. Cozma, "The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?". Revista de Chimie, vol. 70, no. 1, pp. 69-73, 2019. [online]. https://doi.org/10.37358/RC.19.1.6853


Text
Adela Viviana Sitar Taut, Olga Orasan, Adriana Fodor, Anca Daniela Farcas, Simina Tarmure Sarlea, Gabriela Dogaru, Dumitru Tudor Zdrenghea, Dana Pop, Angela Cozma,
The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?,
Revista de Chimie,
Volume 70, Issue 1,
2019,
Pages 69-73,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.1.6853.
(https://revistadechimie.ro/Articles.asp?ID=6853)
Keywords: adhesion molecule; gender; IDF; inflammation; metabolic syndrome


RIS
TY - JOUR
T1 - The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?
A1 - Taut, Adela Viviana Sitar
A2 - Orasan, Olga
A3 - Fodor, Adriana
A4 - Farcas, Anca Daniela
A5 - Sarlea, Simina Tarmure
A6 - Dogaru, Gabriela
A7 - Zdrenghea, Dumitru Tudor
A8 - Pop, Dana
A9 - Cozma, Angela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 1
SP - 69
EP - 73
UR - https://doi.org/10.37358/RC.19.1.6853
KW - adhesion molecule
KW - gender
KW - IDF
KW - inflammation
KW - metabolic syndrome
ER -


BibTex
@article{RevCh2019P69,
author = {Taut Adela Viviana Sitar and Orasan Olga and Fodor Adriana and Farcas Anca Daniela and Sarlea Simina Tarmure and Dogaru Gabriela and Zdrenghea Dumitru Tudor and Pop Dana and Cozma Angela},
title = {The Realtionship Between Inflammation and Metabolic Syndrome (MetS)-A Matter of Gender?},
journal = {Revista de Chimie},
volume = {70},
number = {1},
pages = {69-73},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.1.6853},
url = {https://revistadechimie.ro/Articles.asp?ID=6853}
}
 
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