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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 1, 96-101

https://doi.org/10.37358/RC.19.1.6859

Delia Mira Berceanu Vaduva, Dana Emilia Velimirovici, Livia Stanga, Marcel Mihai Berceanu Vaduva, Smaranda Arghirescu, Adrian Stancu, Horatiu Petrescu, Matilda Radulescu

Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome

Abstract:

Because the TORCH Syndrome groups infectious agents which cross the placenta during pregnancy and due to that cause the majority of malformative fetopaties, our porpose was to determin specific IgG and IgM antibodies for Cytomegalovirus, Rubella virus and Toxoplasma gondii. We studied 95 serum samples from 93 pregnant females and 2 cilds, being analyzed by a private laboratory in Timisoara between july 2015 - june 2016. Specific antibodies IgG and IgM were found for Rubella virus in 75 of the samples, for Cytomegalovirus in 82 and for toxoplasmosis 92. In this process of determination we used Access 2 (Beckman Coulter) and Immulite 1000 (Siemens) analysers, which use the chemiluminescence reaction. For 72 cases (77.42%) specific antibodies for all tests of the TORCH complex were performed. From all the patients 11 chosed to determine antibodies just for one of the infections of the TORCH Syndrome and 10 patients asked for determining of specific antibodies for two infections of the TORCH Syndrome. 53 (64.63%) of the 82 patients tested for anti-CMV IgG specific antibodies had positive result, which signifies former presence of CMV. 64 (85.33%) of the 75 patients tested for anti-rubella specific antibodies had an IgG positive result. Interpreting of results took in counter the vaccinal status. 6 patients (8%) did not contact the Rubella virus and did were not vaccinated. The level of specific IgG anti-Toxoplasma gondii antibodies was positive for 2 (2.17%) patients of 92. IgM specific antibody test was negative. In pregnant women TORCH Syndrome diagnosis is a must, especially if the medical abortion is the correct decision. Identifyeing infectious agents implicated in TORCH Syndrome can lead to an important decrease of maternal and fetal mortality and morbidity.
Keywords:
TORCH Syndrome; Cytomegalovirus; Rubella virus; Toxoplasma gondii; IgG and IgM antibodies/immunoglobulines; the chemiluminescence reaction

Issue: 2019, Volume 70, Issue 1
Pages: 96-101
Publication date: 15/02/2019
https://doi.org/10.37358/RC.19.1.6859
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
VADUVA, D.M.B., VELIMIROVICI, D.E., STANGA, L., VADUVA, M.M.B., ARGHIRESCU, S., STANCU, A., PETRESCU, H., RADULESCU, M., Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome, Rev. Chim., 70(1), 2019, 96-101.

Vancouver
Vaduva DMB, Velimirovici DE, Stanga L, Vaduva MMB, Arghirescu S, Stancu A, Petrescu H, Radulescu M. Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome. Rev. Chim.[internet]. 2019 Jan;70(1):96-101. Available from: https://doi.org/10.37358/RC.19.1.6859


APA 6th edition
Vaduva, D.M.B., Velimirovici, D.E., Stanga, L., Vaduva, M.M.B., Arghirescu, S., Stancu, A., Petrescu, H. & Radulescu, M. (2019). Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome. Revista de Chimie, 70(1), 96-101. https://doi.org/10.37358/RC.19.1.6859


Harvard
Vaduva, D.M.B., Velimirovici, D.E., Stanga, L., Vaduva, M.M.B., Arghirescu, S., Stancu, A., Petrescu, H., Radulescu, M. (2019). 'Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome', Revista de Chimie, 70(1), pp. 96-101. https://doi.org/10.37358/RC.19.1.6859


IEEE
D.M.B. Vaduva, D.E. Velimirovici, L. Stanga, M.M.B. Vaduva, S. Arghirescu, A. Stancu, H. Petrescu, M. Radulescu, "Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome". Revista de Chimie, vol. 70, no. 1, pp. 96-101, 2019. [online]. https://doi.org/10.37358/RC.19.1.6859


Text
Delia Mira Berceanu Vaduva, Dana Emilia Velimirovici, Livia Stanga, Marcel Mihai Berceanu Vaduva, Smaranda Arghirescu, Adrian Stancu, Horatiu Petrescu, Matilda Radulescu,
Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome,
Revista de Chimie,
Volume 70, Issue 1,
2019,
Pages 96-101,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.1.6859.
(https://revistadechimie.ro/Articles.asp?ID=6859)
Keywords: TORCH Syndrome; Cytomegalovirus; Rubella virus; Toxoplasma gondii; IgG and IgM antibodies/immunoglobulines; the chemiluminescence reaction


RIS
TY - JOUR
T1 - Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome
A1 - Vaduva, Delia Mira Berceanu
A2 - Velimirovici, Dana Emilia
A3 - Stanga, Livia
A4 - Vaduva, Marcel Mihai Berceanu
A5 - Arghirescu, Smaranda
A6 - Stancu, Adrian
A7 - Petrescu, Horatiu
A8 - Radulescu, Matilda
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 1
SP - 96
EP - 101
UR - https://doi.org/10.37358/RC.19.1.6859
KW - TORCH Syndrome
KW - Cytomegalovirus
KW - Rubella virus
KW - Toxoplasma gondii
KW - IgG and IgM antibodies/immunoglobulines
KW - the chemiluminescence reaction
ER -


BibTex
@article{RevCh2019P96,
author = {Vaduva Delia Mira Berceanu and Velimirovici Dana Emilia and Stanga Livia and Vaduva Marcel Mihai Berceanu and Arghirescu Smaranda and Stancu Adrian and Petrescu Horatiu and Radulescu Matilda},
title = {Significance of Specific Immunoglobulins Determined by the Chemiluminescence Reaction in Intrauterine Maternal-fetal Infections of TORCH Syndrome},
journal = {Revista de Chimie},
volume = {70},
number = {1},
pages = {96-101},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.1.6859},
url = {https://revistadechimie.ro/Articles.asp?ID=6859}
}
 
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