Victor Vlad Costan, Anca Sava, Alexandru Carauleanu, Claudia Florida Costea, Andrei Ionut Cucu, Gabriela Dimitriu, Gabriela Florenta Dumitrescu, Nicoleta Dumitrescu, Maria Silvia Stoicescu, Gheorghe Raftu, Mihaela Dana Turliuc
Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit
Abstract:
Cavernous venous malformation (CVM) is the most common primary vascular lesion of the orbit. The aim of this study is to present authors ‘experience regarding fourteen patients with orbital CVM (so-called cavernous hemangioma) and identify their clinical and histopathological particular characteristics. From 2010 to 2017 a total of 14 patients were diagnosed with orbital cavernous hemangiomas and treated by the authors. Patients’ socio-demographic, clinical, radiological, and surgical findings were retrospectively retrieved from medical records and analyzed. Diagnosis of a cavernous hemangioma was confirmed histologically in all cases. Results: All 14 patients were females, with a mean age of 44.2 years old, ranging from 13 years to 57 years. The left orbit was affected in eleven (78.57%) cases. A painless, gradually progressive proptosis and visual disturbance were the main clinical signs. In four (28.57%) cases, the lesion was incidentally discovered at imaging evaluations for persistent headache. All patients were accurately diagnosed preoperatively based on computed tomography (CT) exam or magnetic resonance imaging (MRI). The tumors were removed successfully by anterior orbitotomy. Transconjunctival approach proved to be an important surgical procedure in their treatment, with excellent results and a low risk of complications. Histologically, all lesions revealed large vascular channels with endothelium lining and multilaminar smooth muscle layers in their walls, but also nests of small capillary channels in interstitium. No intravascular thrombosis or stromal lymphocytes could be seen. Orbital cavernous hemangiomas presented clinical, imaging and histological features of a benign lesion. Having to deal with extraconal lesions, we successfully used anterior orbitotomy, mainly the transconjuctival approach, with no complications or recurrences after a six-month follow-up period. Histologically, all lesions revealed images being most closely to dysplastic veins. So, we concluded that the so-called orbital cavernous hemangioma was rather a cavernous venous malformation.
Cite this article as: COSTAN, V.V., SAVA, A., CARAULEANU, A., COSTEA, C.F., CUCU, A.I., DIMITRIU, G., DUMITRESCU, G.F., DUMITRESCU, N., STOICESCU, M.S., RAFTU, G., TURLIUC, M.D., Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit, Rev. Chim., 70(1), 2019, 350-354.
Vancouver Costan VV, Sava A, Carauleanu A, Costea CF, Cucu AI, Dimitriu G, Dumitrescu GF, Dumitrescu N, Stoicescu MS, Raftu G, Turliuc MD. Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit. Rev. Chim.[internet]. 2019 Jan;70(1):350-354. Available from: https://doi.org/10.37358/RC.19.1.6914
APA 6th edition Costan, V.V., Sava, A., Carauleanu, A., Costea, C.F., Cucu, A.I., Dimitriu, G.,... Turliuc, M.D. (2019). Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit. Revista de Chimie, 70(1), 350-354. https://doi.org/10.37358/RC.19.1.6914
Harvard Costan, V.V., Sava, A., Carauleanu, A., Costea, C.F., Cucu, A.I., Dimitriu, G., Dumitrescu, G.F., Dumitrescu, N., Stoicescu, M.S., Raftu, G., Turliuc, M.D. (2019). 'Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit', Revista de Chimie, 70(1), pp. 350-354. https://doi.org/10.37358/RC.19.1.6914
IEEE V.V. Costan, A. Sava, A. Carauleanu, C.F. Costea, A.I. Cucu, G. Dimitriu, G.F. Dumitrescu, N. Dumitrescu, M.S. Stoicescu, G. Raftu, M.D. Turliuc, "Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit". Revista de Chimie, vol. 70, no. 1, pp. 350-354, 2019. [online]. https://doi.org/10.37358/RC.19.1.6914
Text Victor Vlad Costan, Anca Sava, Alexandru Carauleanu, Claudia Florida Costea, Andrei Ionut Cucu, Gabriela Dimitriu, Gabriela Florenta Dumitrescu, Nicoleta Dumitrescu, Maria Silvia Stoicescu, Gheorghe Raftu, Mihaela Dana Turliuc, Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit, Revista de Chimie, Volume 70, Issue 1, 2019, Pages 350-354, ISSN 2668-8212, https://doi.org/10.37358/RC.19.1.6914. (https://revistadechimie.ro/Articles.asp?ID=6914) Keywords: orbit; cavernous hemangioma; cavernous venous malformation; histological examination
RIS TY - JOUR T1 - Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit A1 - Costan, Victor Vlad A2 - Sava, Anca A3 - Carauleanu, Alexandru A4 - Costea, Claudia Florida A5 - Cucu, Andrei Ionut A6 - Dimitriu, Gabriela A7 - Dumitrescu, Gabriela Florenta A8 - Dumitrescu, Nicoleta A9 - Stoicescu, Maria Silvia A10 - Raftu, Gheorghe A11 - Turliuc, Mihaela Dana JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2019 VL - 70 IS - 1 SP - 350 EP - 354 UR - https://doi.org/10.37358/RC.19.1.6914 KW - orbit KW - cavernous hemangioma KW - cavernous venous malformation KW - histological examination ER -
BibTex @article{RevCh2019P350, author = {Costan Victor Vlad and Sava Anca and Carauleanu Alexandru and Costea Claudia Florida and Cucu Andrei Ionut and Dimitriu Gabriela and Dumitrescu Gabriela Florenta and Dumitrescu Nicoleta and Stoicescu Maria Silvia and Raftu Gheorghe and Turliuc Mihaela Dana}, title = {Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit}, journal = {Revista de Chimie}, volume = {70}, number = {1}, pages = {350-354}, year = {2019}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.19.1.6914}, url = {https://revistadechimie.ro/Articles.asp?ID=6914} }
