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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 4, 1288-1292

https://doi.org/10.37358/RC.19.4.7111

Natalia Radulea, Rica Boscencu, Radu Socoteanu, Gina Manda, Ionela Victoria Neagoe

The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells

Abstract:

This study include in the same frame promising structures tailored as photoactive agents for photodynamic therapy of cancer versus one of the most versatile cell lines from experimental point of view, fibroblasts type, subcutaneous connective tissues- L929. Transmembrane potential was studied establishing important features in the behavior of chemical vectors against cultured cells via membranar media. Two amphiphilic porphyrins, 5,15-bis-(4-hydroxy-3-methoxyphenyl)-10,20-bis-(4-carboxymethylphenyl)porphyrin and Zn(II)-5,15-bis-(4-hydroxy-3-methoxyphenyl)-10,20-bis-(4-carboxymethylphenyl)porphyrin were assessed in terms of the effect on membrane potential. The comparative effect of free base porphyrin and metalloporphyrin with amphiphilic structure, reveal hyperpolarization phenomena and bring informations about consequences of active compound concentration against cell membrane.
Keywords:
amphiphilic porphyrins; transmembrane potential; mouse L929 fibroblasts

Issue: 2019, Volume 70, Issue 4
Pages: 1288-1292
Publication date: 2019/5/15
https://doi.org/10.37358/RC.19.4.7111
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
RADULEA, N., BOSCENCU, R., SOCOTEANU, R., MANDA, G., NEAGOE, I.V., The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells, Rev. Chim., 70(4), 2019, 1288-1292.

Vancouver
Radulea N, Boscencu R, Socoteanu R, Manda G, Neagoe IV. The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells. Rev. Chim.[internet]. 2019 Apr;70(4):1288-1292. Available from: https://doi.org/10.37358/RC.19.4.7111


APA 6th edition
Radulea, N., Boscencu, R., Socoteanu, R., Manda, G. & Neagoe, I.V. (2019). The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells. Revista de Chimie, 70(4), 1288-1292. https://doi.org/10.37358/RC.19.4.7111


Harvard
Radulea, N., Boscencu, R., Socoteanu, R., Manda, G., Neagoe, I.V. (2019). 'The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells', Revista de Chimie, 70(4), pp. 1288-1292. https://doi.org/10.37358/RC.19.4.7111


IEEE
N. Radulea, R. Boscencu, R. Socoteanu, G. Manda, I.V. Neagoe, "The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells". Revista de Chimie, vol. 70, no. 4, pp. 1288-1292, 2019. [online]. https://doi.org/10.37358/RC.19.4.7111


Text
Natalia Radulea, Rica Boscencu, Radu Socoteanu, Gina Manda, Ionela Victoria Neagoe,
The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells,
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1288-1292,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7111.
(https://revistadechimie.ro/Articles.asp?ID=7111)
Keywords: amphiphilic porphyrins; transmembrane potential; mouse L929 fibroblasts


RIS
TY - JOUR
T1 - The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells
A1 - Radulea, Natalia
A2 - Boscencu, Rica
A3 - Socoteanu, Radu
A4 - Manda, Gina
A5 - Neagoe, Ionela Victoria
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1288
EP - 1292
UR - https://doi.org/10.37358/RC.19.4.7111
KW - amphiphilic porphyrins
KW - transmembrane potential
KW - mouse L929 fibroblasts
ER -


BibTex
@article{RevCh2019P1288,
author = {Radulea Natalia and Boscencu Rica and Socoteanu Radu and Manda Gina and Neagoe Ionela Victoria},
title = {The Effect of Some Amphiphilic Porphyrins on the Transmembrane Potential of Cultured L929 Cells},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1288-1292},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7111},
url = {https://revistadechimie.ro/Articles.asp?ID=7111}
}
 
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