Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies

Albu, Cristina-Crenguta; Cilievici, Suzana Elena; Albu, Dinu-Florin; Albu, Stefan-Dimitrie; Patrascu, Anca; Goganau, Alexandru Marian

Cristina-Crenguta Albu, Suzana Elena Cilievici, Dinu-Florin Albu, Stefan-Dimitrie Albu, Anca Patrascu, Alexandru Marian Goganau

Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies

Abstract:

It was performed a case-control study, that included totally 187 pregnant women hospitalized in Obstetrical-Gynecology Department of Prof. Dr. Panait Sarbu Hospital, Bucharest, Romania. The selection criteria for case sample were: age over 30 years, history of malformative risk, clinical exam that emphasised malformations and ultrasound examination that suspicioned embrio-fetal morphological abnormalities. We determined the serum levels of alpha fetoprotein (AFP), human chorionic gonadotropin (hCG) and unconjugated estriol (uE3), by immunoenzymometry. As statistical analysis we determined the estimated median value. For each of the three parametres, the final curve was compared with the value obtained by spectrophotometry. The study revealed the predictive value of correlated use of these three parameters, together with ultrasound examination and cytogenetic investigations, in order to early prenatal diagnosis of congenital fetal anomalies.

Keywords:
maternal serum screening (MSS); alpha fetoprotein (AFP); human chorionic gonadotropin (hCG); unconjugated estriol (uE3); ultrasound examination

Issue: 2019, Volume 70, Issue 5

Pages: 1534-1538

Publication date: 2019/6/15

https://doi.org/10.37358/RC.19.5.7164

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ALBU, C., CILIEVICI, S.E., ALBU, D., ALBU, S., PATRASCU, A., GOGANAU, A.M., Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies, Rev. Chim., 70(5), 2019, 1534-1538.

Vancouver
Albu C, Cilievici SE, Albu D, Albu S, Patrascu A, Goganau AM. Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies. Rev. Chim.[internet]. 2019 May;70(5):1534-1538. Available from: https://doi.org/10.37358/RC.19.5.7164

APA 6th edition
Albu, C., Cilievici, S.E., Albu, D., Albu, S., Patrascu, A. & Goganau, A.M. (2019). Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies. Revista de Chimie, 70(5), 1534-1538. https://doi.org/10.37358/RC.19.5.7164

Harvard
Albu, C., Cilievici, S.E., Albu, D., Albu, S., Patrascu, A., Goganau, A.M. (2019). 'Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies', Revista de Chimie, 70(5), pp. 1534-1538. https://doi.org/10.37358/RC.19.5.7164

IEEE
C. Albu, S.E. Cilievici, D. Albu, S. Albu, A. Patrascu, A.M. Goganau, "Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies". Revista de Chimie, vol. 70, no. 5, pp. 1534-1538, 2019. [online]. https://doi.org/10.37358/RC.19.5.7164

Text
Cristina-Crenguta Albu, Suzana Elena Cilievici, Dinu-Florin Albu, Stefan-Dimitrie Albu, Anca Patrascu, Alexandru Marian Goganau,
Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies,
Revista de Chimie,
Volume 70, Issue 5,
2019,
Pages 1534-1538,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.5.7164.
(https://revistadechimie.ro/Articles.asp?ID=7164)
Keywords: maternal serum screening (MSS); alpha fetoprotein (AFP); human chorionic gonadotropin (hCG); unconjugated estriol (uE3); ultrasound examination

RIS
TY - JOUR
T1 - Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies
A1 - Albu, Cristina-Crenguta
A2 - Cilievici, Suzana Elena
A3 - Albu, Dinu-Florin
A4 - Albu, Stefan-Dimitrie
A5 - Patrascu, Anca
A6 - Goganau, Alexandru Marian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 5
SP - 1534
EP - 1538
UR - https://doi.org/10.37358/RC.19.5.7164
KW - maternal serum screening (MSS)
KW - alpha fetoprotein (AFP)
KW - human chorionic gonadotropin (hCG)
KW - unconjugated estriol (uE3)
KW - ultrasound examination
ER -

BibTex
@article{RevCh2019P1534,
author = {Albu Cristina-Crenguta and Cilievici Suzana Elena and Albu Dinu-Florin and Albu Stefan-Dimitrie and Patrascu Anca and Goganau Alexandru Marian},
title = {Impact of Material Serum Screening in Early Prenatal Diagnosis and Management of Congenital Anomalies},
journal = {Revista de Chimie},
volume = {70},
number = {5},
pages = {1534-1538},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.5.7164},
url = {https://revistadechimie.ro/Articles.asp?ID=7164}
}

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