The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries

Papacocea, Marius Toma; Badarau, Ioana Anca; Radoi, Mugurel; Papacocea, Ioana Raluca

Marius Toma Papacocea, Ioana Anca Badarau, Mugurel Radoi, Ioana Raluca Papacocea

The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries

Abstract:

Traumatic brain injuries (TBI) represent a high impact public health problem due to a high rate of death , long term disability and occurrence especially in young adults. Despite several promising animal studies, several parameters were proposed as biological markers and were assessed for this aim. Our study proposes the study of the early biochemical changes in association to hematological parameters for severe TBI patients prognosis. 43 patients with acute TBI were included in study based on clinical, laboratory and imagistic findings. The severity of the TBI was established by Glasgow Coma Scale GCS 3-8. In all patients were evaluated hematologic parameters (Red blood cell count - RBC, Hematocrit, blood Hemoglobin, White blood cell - WBC, Platelet count and biochemical parameters (glucose, urea, creatinine, electrolytes). Outcome was expressed as Glasgow Outcome Scale (GOS), between 1-5. Values were compared to control group -15 cases. Significant early differences in body temperature, heart rate, and systolic blood pressure were observed in TBI group versus control (p[0.05). After correlation, laboratory findings significantly associated to severe outcome - GOS = 1, 2 - (p[0.05) were plasma Na decrease and significant glucose increase. An early increase of temperature and decrease of Na may predict a severe outcome in patients with acute TBI; association with shifts in heart rate and blood pressure, imposes aggressive treatment measures.

Keywords:
traumatic brain injury; hyponatremia; glucose

Issue: 2019, Volume 70, Issue 5

Pages: 1754-1757

Publication date: 2019/6/15

https://doi.org/10.37358/RC.19.5.7209

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
PAPACOCEA, M.T., BADARAU, I.A., RADOI, M., PAPACOCEA, I.R., The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries, Rev. Chim., 70(5), 2019, 1754-1757.

Vancouver
Papacocea MT, Badarau IA, Radoi M, Papacocea IR. The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries. Rev. Chim.[internet]. 2019 May;70(5):1754-1757. Available from: https://doi.org/10.37358/RC.19.5.7209

APA 6th edition
Papacocea, M.T., Badarau, I.A., Radoi, M. & Papacocea, I.R. (2019). The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries. Revista de Chimie, 70(5), 1754-1757. https://doi.org/10.37358/RC.19.5.7209

Harvard
Papacocea, M.T., Badarau, I.A., Radoi, M., Papacocea, I.R. (2019). 'The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries', Revista de Chimie, 70(5), pp. 1754-1757. https://doi.org/10.37358/RC.19.5.7209

IEEE
M.T. Papacocea, I.A. Badarau, M. Radoi, I.R. Papacocea, "The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries". Revista de Chimie, vol. 70, no. 5, pp. 1754-1757, 2019. [online]. https://doi.org/10.37358/RC.19.5.7209

Text
Marius Toma Papacocea, Ioana Anca Badarau, Mugurel Radoi, Ioana Raluca Papacocea,
The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries,
Revista de Chimie,
Volume 70, Issue 5,
2019,
Pages 1754-1757,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.5.7209.
(https://revistadechimie.ro/Articles.asp?ID=7209)
Keywords: traumatic brain injury; hyponatremia; glucose

RIS
TY - JOUR
T1 - The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries
A1 - Papacocea, Marius Toma
A2 - Badarau, Ioana Anca
A3 - Radoi, Mugurel
A4 - Papacocea, Ioana Raluca
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 5
SP - 1754
EP - 1757
UR - https://doi.org/10.37358/RC.19.5.7209
KW - traumatic brain injury
KW - hyponatremia
KW - glucose
ER -

BibTex
@article{RevCh2019P1754,
author = {Papacocea Marius Toma and Badarau Ioana Anca and Radoi Mugurel and Papacocea Ioana Raluca},
title = {The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries},
journal = {Revista de Chimie},
volume = {70},
number = {5},
pages = {1754-1757},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.5.7209},
url = {https://revistadechimie.ro/Articles.asp?ID=7209}
}

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