The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania

Golli, Andreea-Loredana; Nitu, Floarea Mimi; Balasoiu, Maria; Lungu, Marina Alina; Dragomirescu, Cristiana Cerasella; Olteanu, Madalina; Nemes, Roxana Maria; Tantu, Monica Marilena; Olteanu, Mihai

Andreea-Loredana Golli, Floarea Mimi Nitu, Maria Balasoiu, Marina Alina Lungu, Cristiana Cerasella Dragomirescu, Madalina Olteanu, Roxana Maria Nemes, Monica Marilena Tantu, Mihai Olteanu

The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania

Abstract:

To determine the resistance pattern of bacterial pathogens involved in infections of the patients aged between 18-64 years, admitted in a ICU from a 1518-bed university-affiliated hospital. A retrospective study of bacterial pathogens was carried out on 351 patients aged between 18-64 years admitted to the ICU, from January to December 2017. In this study there were analysed 469 samples from 351 patients (18-64 years). A total of 566 bacterial isolates were obtained, of which 120 strains of Klebsiella spp. (35.39%%), followed by Nonfermenting Gram negative bacilli, other than Pseudomonas and Acinetobacter (NFB) (75- 22.12%), Acinetobacter spp. (53 - 15.63%), Pseudomonas aeruginosa and Proteus (51 - 15.04%), and Escherichia coli (49 - 14.45%). The most common isolates were from respiratory tract (394 isolates - 69.61%). High rates of MDR were found for Pseudomonas aeruginosa (64.70%), MRSA (62.65%) and Klebsiella spp. (53.33%), while almost all of the isolated NFB strains were MDR (97.33%). There was statistic difference between the drug resistance rate of Klebsiella and E. coli strains to ceftazidime and ceftriaxone (p[0.001), cefuroxime (p[0.01) and to cefepime (p[0.01). The study revealed an alarming pattern of antibiotic resistance in the majority of ICU isolates.

Keywords:
multidrug resistance (MDR); intensive care unit; bacterial pathogen

Issue: 2019, Volume 70, Issue 5

Pages: 1778-1783

Publication date: 2019/6/15

https://doi.org/10.37358/RC.19.5.7214

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GOLLI, A., NITU, F.M., BALASOIU, M., LUNGU, M.A., DRAGOMIRESCU, C.C., OLTEANU, M., NEMES, R.M., TANTU, M.M., OLTEANU, M., The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania, Rev. Chim., 70(5), 2019, 1778-1783.

Vancouver
Golli A, Nitu FM, Balasoiu M, Lungu MA, Dragomirescu CC, Olteanu M, Nemes RM, Tantu MM, Olteanu M. The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania. Rev. Chim.[internet]. 2019 May;70(5):1778-1783. Available from: https://doi.org/10.37358/RC.19.5.7214

APA 6th edition
Golli, A., Nitu, F.M., Balasoiu, M., Lungu, M.A., Dragomirescu, C.C., Olteanu, M.,... Olteanu, M. (2019). The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania. Revista de Chimie, 70(5), 1778-1783. https://doi.org/10.37358/RC.19.5.7214

Harvard
Golli, A., Nitu, F.M., Balasoiu, M., Lungu, M.A., Dragomirescu, C.C., Olteanu, M., Nemes, R.M., Tantu, M.M., Olteanu, M. (2019). 'The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania', Revista de Chimie, 70(5), pp. 1778-1783. https://doi.org/10.37358/RC.19.5.7214

IEEE
A. Golli, F.M. Nitu, M. Balasoiu, M.A. Lungu, C.C. Dragomirescu, M. Olteanu, R.M. Nemes, M.M. Tantu, M. Olteanu, "The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania". Revista de Chimie, vol. 70, no. 5, pp. 1778-1783, 2019. [online]. https://doi.org/10.37358/RC.19.5.7214

Text
Andreea-Loredana Golli, Floarea Mimi Nitu, Maria Balasoiu, Marina Alina Lungu, Cristiana Cerasella Dragomirescu, Madalina Olteanu, Roxana Maria Nemes, Monica Marilena Tantu, Mihai Olteanu,
The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania,
Revista de Chimie,
Volume 70, Issue 5,
2019,
Pages 1778-1783,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.5.7214.
(https://revistadechimie.ro/Articles.asp?ID=7214)
Keywords: multidrug resistance (MDR); intensive care unit; bacterial pathogen

RIS
TY - JOUR
T1 - The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania
A1 - Golli, Andreea-Loredana
A2 - Nitu, Floarea Mimi
A3 - Balasoiu, Maria
A4 - Lungu, Marina Alina
A5 - Dragomirescu, Cristiana Cerasella
A6 - Olteanu, Madalina
A7 - Nemes, Roxana Maria
A8 - Tantu, Monica Marilena
A9 - Olteanu, Mihai
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 5
SP - 1778
EP - 1783
UR - https://doi.org/10.37358/RC.19.5.7214
KW - multidrug resistance (MDR)
KW - intensive care unit
KW - bacterial pathogen
ER -

BibTex
@article{RevCh2019P1778,
author = {Golli Andreea-Loredana and Nitu Floarea Mimi and Balasoiu Maria and Lungu Marina Alina and Dragomirescu Cristiana Cerasella and Olteanu Madalina and Nemes Roxana Maria and Tantu Monica Marilena and Olteanu Mihai},
title = {The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania},
journal = {Revista de Chimie},
volume = {70},
number = {5},
pages = {1778-1783},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.5.7214},
url = {https://revistadechimie.ro/Articles.asp?ID=7214}
}

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