Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles

Araniciu, Catalin; Oniga, Smaranda Dafina; Stoica, Cristina Ioana; Chifiriuc, Mariana Carmen; Popa, Marcela; Vlase, Laurian; Palage, Mariana; Oniga, Ovidiu

Catalin Araniciu, Smaranda Dafina Oniga, Cristina Ioana Stoica, Mariana Carmen Chifiriuc, Marcela Popa, Laurian Vlase, Mariana Palage, Ovidiu Oniga

Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles

Abstract:

Considering the promising antimicrobial activity of compounds bearing the thiazole or the oxadiazole rings in their structures, we set out to obtain new antimicrobial molecules bearing the 2-(thiazol-5-yl)-1,3,4-oxadiazole schaffold. The structures of the 8 new compounds obtained was confirmed by physicochemical characterization including: 1H-NMR, MS and elemental analysis. Antimicrobial activity was investigated against 5 Gram-positive bacterial strains, 2 Gram-negative bacterial strains and 2 fungal strains. The newly synthesized compounds showed modest antimicrobial activity.

Keywords:
thiazole; oxadiazole; antibacterial; antifungal

Issue: 2019, Volume 70, Issue 6

Pages: 1996-1999

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7262

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ARANICIU, C., ONIGA, S.D., STOICA, C.I., CHIFIRIUC, M.C., POPA, M., VLASE, L., PALAGE, M., ONIGA, O., Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles, Rev. Chim., 70(6), 2019, 1996-1999.

Vancouver
Araniciu C, Oniga SD, Stoica CI, Chifiriuc MC, Popa M, Vlase L, Palage M, Oniga O. Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles. Rev. Chim.[internet]. 2019 Jun;70(6):1996-1999. Available from: https://doi.org/10.37358/RC.19.6.7262

APA 6th edition
Araniciu, C., Oniga, S.D., Stoica, C.I., Chifiriuc, M.C., Popa, M., Vlase, L., Palage, M. & Oniga, O. (2019). Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles. Revista de Chimie, 70(6), 1996-1999. https://doi.org/10.37358/RC.19.6.7262

Harvard
Araniciu, C., Oniga, S.D., Stoica, C.I., Chifiriuc, M.C., Popa, M., Vlase, L., Palage, M., Oniga, O. (2019). 'Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles', Revista de Chimie, 70(6), pp. 1996-1999. https://doi.org/10.37358/RC.19.6.7262

IEEE
C. Araniciu, S.D. Oniga, C.I. Stoica, M.C. Chifiriuc, M. Popa, L. Vlase, M. Palage, O. Oniga, "Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles". Revista de Chimie, vol. 70, no. 6, pp. 1996-1999, 2019. [online]. https://doi.org/10.37358/RC.19.6.7262

Text
Catalin Araniciu, Smaranda Dafina Oniga, Cristina Ioana Stoica, Mariana Carmen Chifiriuc, Marcela Popa, Laurian Vlase, Mariana Palage, Ovidiu Oniga,
Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 1996-1999,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7262.
(https://revistadechimie.ro/Articles.asp?ID=7262)
Keywords: thiazole; oxadiazole; antibacterial; antifungal

RIS
TY - JOUR
T1 - Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles
A1 - Araniciu, Catalin
A2 - Oniga, Smaranda Dafina
A3 - Stoica, Cristina Ioana
A4 - Chifiriuc, Mariana Carmen
A5 - Popa, Marcela
A6 - Vlase, Laurian
A7 - Palage, Mariana
A8 - Oniga, Ovidiu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 1996
EP - 1999
UR - https://doi.org/10.37358/RC.19.6.7262
KW - thiazole
KW - oxadiazole
KW - antibacterial
KW - antifungal
ER -

BibTex
@article{RevCh2019P1996,
author = {Araniciu Catalin and Oniga Smaranda Dafina and Stoica Cristina Ioana and Chifiriuc Mariana Carmen and Popa Marcela and Vlase Laurian and Palage Mariana and Oniga Ovidiu},
title = {Synthesis and Antimicrobial Assessment of Some New 2-(Thiazol-5-yl)-1,3,4-oxadiazoles},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {1996-1999},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7262},
url = {https://revistadechimie.ro/Articles.asp?ID=7262}
}

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