Silvia Robu, Aurelia Romila, Olimpia Dumitriu Buzia, Adrian Florin Spac, Camelia Diaconu, Dana Tutunaru, Elena Lisa, Aurel Nechita
Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis
Abstract:
Numerous articles on Salvia officinalis L. have been published regarding the composition of their essential oil. The considerable variation found may be due to the quality of the plant material as well as to the methods used for analysis. A simple GC-MS method was developed and optimized in the QbD approach, for the determination of sage essential oils. The optimization of GC-MS analysis was performed using different mobile phase flows, injection volumes, split ratios and temperature programs. The optimized method proved to be simple and can be successfully applied for the determination of sage essential oils.
Cite this article as: ROBU, S., ROMILA, A., BUZIA, O.D., SPAC, A.F., DIACONU, C., TUTUNARU, D., LISA, E., NECHITA, A., Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis, Rev. Chim., 70(6), 2019, 2015-2020.
Vancouver Robu S, Romila A, Buzia OD, Spac AF, Diaconu C, Tutunaru D, Lisa E, Nechita A. Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis. Rev. Chim.[internet]. 2019 Jun;70(6):2015-2020. Available from: https://doi.org/10.37358/RC.19.6.7266
APA 6th edition Robu, S., Romila, A., Buzia, O.D., Spac, A.F., Diaconu, C., Tutunaru, D., Lisa, E. & Nechita, A. (2019). Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis. Revista de Chimie, 70(6), 2015-2020. https://doi.org/10.37358/RC.19.6.7266
Harvard Robu, S., Romila, A., Buzia, O.D., Spac, A.F., Diaconu, C., Tutunaru, D., Lisa, E., Nechita, A. (2019). 'Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis', Revista de Chimie, 70(6), pp. 2015-2020. https://doi.org/10.37358/RC.19.6.7266
IEEE S. Robu, A. Romila, O.D. Buzia, A.F. Spac, C. Diaconu, D. Tutunaru, E. Lisa, A. Nechita, "Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis". Revista de Chimie, vol. 70, no. 6, pp. 2015-2020, 2019. [online]. https://doi.org/10.37358/RC.19.6.7266
Text Silvia Robu, Aurelia Romila, Olimpia Dumitriu Buzia, Adrian Florin Spac, Camelia Diaconu, Dana Tutunaru, Elena Lisa, Aurel Nechita, Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis, Revista de Chimie, Volume 70, Issue 6, 2019, Pages 2015-2020, ISSN 2668-8212, https://doi.org/10.37358/RC.19.6.7266. (https://revistadechimie.ro/Articles.asp?ID=7266) Keywords: sage; GC-MS; QbD; essential oil
RIS TY - JOUR T1 - Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis A1 - Robu, Silvia A2 - Romila, Aurelia A3 - Buzia, Olimpia Dumitriu A4 - Spac, Adrian Florin A5 - Diaconu, Camelia A6 - Tutunaru, Dana A7 - Lisa, Elena A8 - Nechita, Aurel JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2019 VL - 70 IS - 6 SP - 2015 EP - 2020 UR - https://doi.org/10.37358/RC.19.6.7266 KW - sage KW - GC-MS KW - QbD KW - essential oil ER -
BibTex @article{RevCh2019P2015, author = {Robu Silvia and Romila Aurelia and Buzia Olimpia Dumitriu and Spac Adrian Florin and Diaconu Camelia and Tutunaru Dana and Lisa Elena and Nechita Aurel}, title = {Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis}, journal = {Revista de Chimie}, volume = {70}, number = {6}, pages = {2015-2020}, year = {2019}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.19.6.7266}, url = {https://revistadechimie.ro/Articles.asp?ID=7266} }
