Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression

Gavril, Raluca; Hritcu, Luminita; Padurariu, Manuela; Ciobica, Alin; Horhogea, Cristina; Stefanescu, Gabriela; Spataru, Mihaela Claudia; Straulea, Crina; Stefanescu, Cristinel

Raluca Gavril, Luminita Hritcu, Manuela Padurariu, Alin Ciobica, Cristina Horhogea, Gabriela Stefanescu, Mihaela Claudia Spataru, Crina Straulea, Cristinel Stefanescu

Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression

Abstract:

Lately there are increased evidences that oxytocin may be an important mediator in several psychiatric disorders including depression and anxiety. Oxytocin system seems to be linked with several neurotransmitters important in psychiatric disorder, but also with the hypothalamic-pituitary-adrenal (HPA) axis and is also a key factor in stress regulation mechanisms. Considering the oxytocin receptor pattern of distribution both central and peripherally and the growing data concerning the disbalance of oxytocin in psychiatric disorders we may speculate that oxytocin system may be at the core of psychosomatic disturbances. Also, recent data brought to attention that oxytocin receptor is distributed throughout gastrointestinal tract. Our hypothesis of the present study was that oxytocin system is disbalanced in irritable bowel syndrome considering also the psychological component of this digestive disorder. We preliminary report here a significant decrease of serum oxytocin levels in patients with major depression disorder and irritable bowel syndrome, as compared with those with major depression disorder alone.

Keywords:
oxytocin; serum; depression; irritable bowel syndrome

Issue: 2019, Volume 70, Issue 6

Pages: 2204-2206

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7305

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GAVRIL, R., HRITCU, L., PADURARIU, M., CIOBICA, A., HORHOGEA, C., STEFANESCU, G., SPATARU, M.C., STRAULEA, C., STEFANESCU, C., Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression, Rev. Chim., 70(6), 2019, 2204-2206.

Vancouver
Gavril R, Hritcu L, Padurariu M, Ciobica A, Horhogea C, Stefanescu G, Spataru MC, Straulea C, Stefanescu C. Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression. Rev. Chim.[internet]. 2019 Jun;70(6):2204-2206. Available from: https://doi.org/10.37358/RC.19.6.7305

APA 6th edition
Gavril, R., Hritcu, L., Padurariu, M., Ciobica, A., Horhogea, C., Stefanescu, G.,... Stefanescu, C. (2019). Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression. Revista de Chimie, 70(6), 2204-2206. https://doi.org/10.37358/RC.19.6.7305

Harvard
Gavril, R., Hritcu, L., Padurariu, M., Ciobica, A., Horhogea, C., Stefanescu, G., Spataru, M.C., Straulea, C., Stefanescu, C. (2019). 'Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression', Revista de Chimie, 70(6), pp. 2204-2206. https://doi.org/10.37358/RC.19.6.7305

IEEE
R. Gavril, L. Hritcu, M. Padurariu, A. Ciobica, C. Horhogea, G. Stefanescu, M.C. Spataru, C. Straulea, C. Stefanescu, "Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression". Revista de Chimie, vol. 70, no. 6, pp. 2204-2206, 2019. [online]. https://doi.org/10.37358/RC.19.6.7305

Text
Raluca Gavril, Luminita Hritcu, Manuela Padurariu, Alin Ciobica, Cristina Horhogea, Gabriela Stefanescu, Mihaela Claudia Spataru, Crina Straulea, Cristinel Stefanescu,
Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2204-2206,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7305.
(https://revistadechimie.ro/Articles.asp?ID=7305)
Keywords: oxytocin; serum; depression; irritable bowel syndrome

RIS
TY - JOUR
T1 - Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression
A1 - Gavril, Raluca
A2 - Hritcu, Luminita
A3 - Padurariu, Manuela
A4 - Ciobica, Alin
A5 - Horhogea, Cristina
A6 - Stefanescu, Gabriela
A7 - Spataru, Mihaela Claudia
A8 - Straulea, Crina
A9 - Stefanescu, Cristinel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2204
EP - 2206
UR - https://doi.org/10.37358/RC.19.6.7305
KW - oxytocin
KW - serum
KW - depression
KW - irritable bowel syndrome
ER -

BibTex
@article{RevCh2019P2204,
author = {Gavril Raluca and Hritcu Luminita and Padurariu Manuela and Ciobica Alin and Horhogea Cristina and Stefanescu Gabriela and Spataru Mihaela Claudia and Straulea Crina and Stefanescu Cristinel},
title = {Preliminary Study on the Correlations Between Oxytocin Levels and Irritable Bowel Syndrome in Patients with Depression},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2204-2206},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7305},
url = {https://revistadechimie.ro/Articles.asp?ID=7305}
}

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