Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale

Zaharescu, Anamaria; Solomon, Sorina Mihaela; Luca, Mihaela Gabriela; Toma, Vasilica; Luchian, Ionut; Sufaru, Irina Georgeta; Martu, Maria Alexandra; Foia, Liliana; Martu, Silvia

Anamaria Zaharescu, Sorina Mihaela Solomon, Mihaela Gabriela Luca, Vasilica Toma, Ionut Luchian, Irina Georgeta Sufaru, Maria Alexandra Martu, Liliana Foia, Silvia Martu

Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale

Abstract:

The present research proposes an assessment of the localized inflammatory burden but also at the systemic level by quantitating the pro-inflammatory molecules (IL1-a, IL1-b, IL2, IL12, IFN-g, TNF-a) with endo-periodontal lesions. The study was performed on a group of 146 subjects who, following clinical and radiological examinations, were divided into five groups: healthy endo-periodontal patients, patients with periodontitis, patients with moderate periodontitis, patients with severe periodontitis and patients presenting combined endo-periodontal lesions. IL1-a, IL1-b, IL2, IL12, IFN-g, TNF-a were analysed in crevicular fluid by ELISA and serum by fluorescence flowcytometry. IL1-a and IL1-b showed serum and crevicular fluid values significantly higher than the healthy subjects. Values for IL2, IL12, TNF-a and IFN-g measured in crevicular fluid were higher for groups II, III, IV, and V compared to the group of healthy endo-periodontal subjects. IL2 showed significantly higher serum values for groups III, IV and V than group I. Serum IL12 values were significantly higher than healthy periodontal subjects only for patients with severe periodontitis and endo-periodontal syndrome. Following serum determinations of proinflammatory molecules, patients with endo-periodontal lesions demonstrated significantly higher values even in subjects with severe periodontitis; these data indicate a much higher risk for these patients to develop and maintain systemic maladies, as is the role local inflammation can play over the general inflammatory status of the patient.

Keywords:
proinflammatory molecules; periodontal disease; endo-periodontal lesions

Issue: 2019, Volume 70, Issue 6

Pages: 2252-2255

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7316

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ZAHARESCU, A., SOLOMON, S.M., LUCA, M.G., TOMA, V., LUCHIAN, I., SUFARU, I.G., MARTU, M.A., FOIA, L., MARTU, S., Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale, Rev. Chim., 70(6), 2019, 2252-2255.

Vancouver
Zaharescu A, Solomon SM, Luca MG, Toma V, Luchian I, Sufaru IG, Martu MA, Foia L, Martu S. Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale. Rev. Chim.[internet]. 2019 Jun;70(6):2252-2255. Available from: https://doi.org/10.37358/RC.19.6.7316

APA 6th edition
Zaharescu, A., Solomon, S.M., Luca, M.G., Toma, V., Luchian, I., Sufaru, I.G.,... Martu, S. (2019). Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale. Revista de Chimie, 70(6), 2252-2255. https://doi.org/10.37358/RC.19.6.7316

Harvard
Zaharescu, A., Solomon, S.M., Luca, M.G., Toma, V., Luchian, I., Sufaru, I.G., Martu, M.A., Foia, L., Martu, S. (2019). 'Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale', Revista de Chimie, 70(6), pp. 2252-2255. https://doi.org/10.37358/RC.19.6.7316

IEEE
A. Zaharescu, S.M. Solomon, M.G. Luca, V. Toma, I. Luchian, I.G. Sufaru, M.A. Martu, L. Foia, S. Martu, "Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale". Revista de Chimie, vol. 70, no. 6, pp. 2252-2255, 2019. [online]. https://doi.org/10.37358/RC.19.6.7316

Text
Anamaria Zaharescu, Sorina Mihaela Solomon, Mihaela Gabriela Luca, Vasilica Toma, Ionut Luchian, Irina Georgeta Sufaru, Maria Alexandra Martu, Liliana Foia, Silvia Martu,
Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2252-2255,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7316.
(https://revistadechimie.ro/Articles.asp?ID=7316)
Keywords: proinflammatory molecules; periodontal disease; endo-periodontal lesions

RIS
TY - JOUR
T1 - Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale
A1 - Zaharescu, Anamaria
A2 - Solomon, Sorina Mihaela
A3 - Luca, Mihaela Gabriela
A4 - Toma, Vasilica
A5 - Luchian, Ionut
A6 - Sufaru, Irina Georgeta
A7 - Martu, Maria Alexandra
A8 - Foia, Liliana
A9 - Martu, Silvia
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2252
EP - 2255
UR - https://doi.org/10.37358/RC.19.6.7316
KW - proinflammatory molecules
KW - periodontal disease
KW - endo-periodontal lesions
ER -

BibTex
@article{RevCh2019P2252,
author = {Zaharescu Anamaria and Solomon Sorina Mihaela and Luca Mihaela Gabriela and Toma Vasilica and Luchian Ionut and Sufaru Irina Georgeta and Martu Maria Alexandra and Foia Liliana and Martu Silvia},
title = {Cuantificarea moleculelor proinflamatorii (IL1-alfa, IL1-beta, IL2, IL 12, IFN-gama, TNF-alfa) in lichid crevicular si ser la pacientii cu leziuni endo-parodontale},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2252-2255},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7316},
url = {https://revistadechimie.ro/Articles.asp?ID=7316}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)

News, Events

Gold Open Access | Source=http://www.plos.org/ | Author=art designer at PLoS

Conferences of Contemporary
Chemistry

Biblioteca Chimiei

Materiale Plastice

REVISTA DE CHIMIE

About

Board

Indexing