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Revista de Chimie, Volume 70, Issue 7, pp. 2439-2441 (2019)
https://doi.org/10.37358/RC.19.7.7357

Gratiela Livia Mihai, Ioana Anca Badarau, Cristian Scheau, Marius Toma Papacocea, Ioana Raluca Papacocea

Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons

Abstract:

Determining neural viability in cell cultures is an essential element in both fundamental and clinical research, including testing the efficacy of certain neuroprotective drug compounds. Therefore, for a more rigorous evaluation of neuronal death associated with either experimental conditions or experimental models of neurological diseases, it is important that the research method and especially the staining method does not produce additional neural injuries and does not change the number destroyed cells. In the present study we tested how several types of dyes: Trypan Blue (TB), Calcein AM, Hoechst 33342, Propidium Iodide and WST-1/Formazan, affect neuronal viability in cell cultures before and after hypoxia and also, which dyes are associated with a higher percentage of cytotoxicity.
Keywords:
cytotoxicity; dyes; cell cultures

Issue: 2019 Volume 70, Number 7
Pages: 2439-2441
https://doi.org/10.37358/RC.19.7.7357
download pdf   Download Pdf Article
Citation Styles
Cite this article as:
MIHAI, G.L., BADARAU, I.A., SCHEAU, C., PAPACOCEA, M.T., PAPACOCEA, I.R., Rev.Chim., 70, no. 7, 2019, p. 2439

Vancouver
Mihai GL, Badarau IA, Scheau C, Papacocea MT, Papacocea IR. Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons. REV.CHIM.[internet]. 2019 Jul;70(7):2439-2441. Available from: https://doi.org/10.37358/RC.19.7.7357


APA 6th edition
Mihai, G.L., Badarau, I.A., Scheau, C., Papacocea, M.T. & Papacocea, I.R. (2019). Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons. Revista de Chimie, 70(7), 2439-2441. https://doi.org/10.37358/RC.19.7.7357


Harvard
Mihai, G.L., Badarau, I.A., Scheau, C., Papacocea, M.T., Papacocea, I.R. (2019). 'Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons', Revista de Chimie, 70(7), pp. 2439-2441. https://doi.org/10.37358/RC.19.7.7357


IEEE
G.L. Mihai, I.A. Badarau, C. Scheau, M.T. Papacocea, I.R. Papacocea, "Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons". Revista de Chimie, vol. 70, no. 7, pp. 2439-2441, 2019. [online]. https://doi.org/10.37358/RC.19.7.7357


Text
Gratiela Livia Mihai, Ioana Anca Badarau, Cristian Scheau, Marius Toma Papacocea, Ioana Raluca Papacocea,
Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons,
Revista de Chimie,
Volume 70, Issue 7,
2019,
Pages 2439-2441,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.7.7357.
(https://revistadechimie.ro/Articles.asp?ID=7357)
Keywords: cytotoxicity; dyes; cell cultures


RIS
TY - JOUR
T1 - Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons
A1 - Mihai, Gratiela Livia
A2 - Badarau, Ioana Anca
A3 - Scheau, Cristian
A4 - Papacocea, Marius Toma
A5 - Papacocea, Ioana Raluca
JF - Revista de Chimie
JO - Rev.Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 7
SP - 2439
EP - 2441
UR - https://doi.org/10.37358/RC.19.7.7357
KW - cytotoxicity
KW - dyes
KW - cell cultures
ER -


BibTex
@article{RevCh2019P2439,
author = {Mihai Gratiela Livia and Badarau Ioana Anca and Scheau Cristian and Papacocea Marius Toma and Papacocea Ioana Raluca},
title = {Comparative Study of the Dyes Induced Citotoxicity in Cultures of Cerebelar Granular Neurons},
journal = {Revista de Chimie},
volume = {70},
number = {7},
pages = {2439-2441},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.7.7357},
url = {https://revistadechimie.ro/Articles.asp?ID=7357}
}
 
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