Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines

Georgescu, Emilian; Dumitrascu, Florea; Georgescu, Florentina; Draghici, Constantin; Dumitrescu, Denisa

Emilian Georgescu, Florea Dumitrascu, Florentina Georgescu, Constantin Draghici, Denisa Dumitrescu

Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines

Abstract:

A library of new pyrrolo[1,2-c]quinazoline derivatives was obtained by the one-pot, three-component microwave-assisted synthesis, starting from quinazolines, 2-bromoacetyl derivatives and electron-deficient alkynes in 1,2-epoxybutane via 1,3-dipolar cycloaddition of quinazolinium N-ylides. This synthetic pathway offers a simple and rapid access to a large range of pyrrolo[1,2-c]quinazoline derivatives.

Keywords:
pyrrolo<1;2-c>quinazolines; microwave-assisted synthesis; one-pot three components reactions; 1;3-dipolar cycloadditions

Issue: 2019, Volume 70, Issue 9

Pages: 3094-3099

Publication date: 2019/10/15

https://doi.org/10.37358/RC.19.9.7495

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GEORGESCU, E., DUMITRASCU, F., GEORGESCU, F., DRAGHICI, C., DUMITRESCU, D., Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines, Rev. Chim., 70(9), 2019, 3094-3099.

Vancouver
Georgescu E, Dumitrascu F, Georgescu F, Draghici C, Dumitrescu D. Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines. Rev. Chim.[internet]. 2019 Sep;70(9):3094-3099. Available from: https://doi.org/10.37358/RC.19.9.7495

APA 6th edition
Georgescu, E., Dumitrascu, F., Georgescu, F., Draghici, C. & Dumitrescu, D. (2019). Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines. Revista de Chimie, 70(9), 3094-3099. https://doi.org/10.37358/RC.19.9.7495

Harvard
Georgescu, E., Dumitrascu, F., Georgescu, F., Draghici, C., Dumitrescu, D. (2019). 'Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines', Revista de Chimie, 70(9), pp. 3094-3099. https://doi.org/10.37358/RC.19.9.7495

IEEE
E. Georgescu, F. Dumitrascu, F. Georgescu, C. Draghici, D. Dumitrescu, "Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines". Revista de Chimie, vol. 70, no. 9, pp. 3094-3099, 2019. [online]. https://doi.org/10.37358/RC.19.9.7495

Text
Emilian Georgescu, Florea Dumitrascu, Florentina Georgescu, Constantin Draghici, Denisa Dumitrescu,
Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines,
Revista de Chimie,
Volume 70, Issue 9,
2019,
Pages 3094-3099,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.9.7495.
(https://revistadechimie.ro/Articles.asp?ID=7495)
Keywords: pyrrolo<1;2-c>quinazolines; microwave-assisted synthesis; one-pot three components reactions; 1;3-dipolar cycloadditions

RIS
TY - JOUR
T1 - Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines
A1 - Georgescu, Emilian
A2 - Dumitrascu, Florea
A3 - Georgescu, Florentina
A4 - Draghici, Constantin
A5 - Dumitrescu, Denisa
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 9
SP - 3094
EP - 3099
UR - https://doi.org/10.37358/RC.19.9.7495
KW - pyrrolo<1
KW - 2-c>quinazolines
KW - microwave-assisted synthesis
KW - one-pot three components reactions
KW - 1
KW - 3-dipolar cycloadditions
ER -

BibTex
@article{RevCh2019P3094,
author = {Georgescu Emilian and Dumitrascu Florea and Georgescu Florentina and Draghici Constantin and Dumitrescu Denisa},
title = {Microwave - Assisted Synthesis of a Library of Pyrrolo<1,2-c>quinazolines},
journal = {Revista de Chimie},
volume = {70},
number = {9},
pages = {3094-3099},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.9.7495},
url = {https://revistadechimie.ro/Articles.asp?ID=7495}
}

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