Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis

Filip, Alexandru; Badulescu, Oana Viola; Sirbu, Paul Dan; Cojocaru, Elena; Filip, Nina; Puha, Gabriela; Trandafir, Laura; Iancu, Cristina; Trandafirescu, Mioara Florentina; Alexa, Ovidiu

Alexandru Filip, Oana Viola Badulescu, Paul Dan Sirbu, Elena Cojocaru, Nina Filip, Gabriela Puha, Laura Trandafir, Cristina Iancu, Mioara Florentina Trandafirescu, Ovidiu Alexa

Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis

Abstract:

Although there are studies showing the link between homocysteine and bone quality, the relationship remains controversial. The purpose of the study was to investigate homocysteine levels in patients with fragility fractures of the pelvis and their association with serum Total Antioxidant Status.The study included a group of 60 patients, aged ]65years, with pelvic fragility fractures and osteoporosis admitted in our trauma department between January 2015 and January 2018 and a control group of 30 patients, aged ]65years without fragility fractures or osteoporosis.The total antioxidant status (TAS) and homocysteine (Hcy) concentrations were determined in serum of all the patients. TAS levels had a significantly lower values in the group with pelvic fragility fractures compared with the control group (p[0.001).We noticed a significant higher mean of Hcy levels (p[0.001) in patients with pelvic fragility fractures compared with the control group. As conclusion this study shows that patients with fragility fractures of the pelvis have moderately elevated levels of homocysteine and reduced serum Total Antioxidant Status.

Keywords:
fragility fracture; homocysteine; osteoporosis; oxidative stress

Issue: 2019, Volume 70, Issue 9

Pages: 3216-3219

Publication date: 2019/10/15

https://doi.org/10.37358/RC.19.9.7520

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
FILIP, A., BADULESCU, O.V., SIRBU, P.D., COJOCARU, E., FILIP, N., PUHA, G., TRANDAFIR, L., IANCU, C., TRANDAFIRESCU, M.F., ALEXA, O., Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis, Rev. Chim., 70(9), 2019, 3216-3219.

Vancouver
Filip A, Badulescu OV, Sirbu PD, Cojocaru E, Filip N, Puha G, Trandafir L, Iancu C, Trandafirescu MF, Alexa O. Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis. Rev. Chim.[internet]. 2019 Sep;70(9):3216-3219. Available from: https://doi.org/10.37358/RC.19.9.7520

APA 6th edition
Filip, A., Badulescu, O.V., Sirbu, P.D., Cojocaru, E., Filip, N., Puha, G.,... Alexa, O. (2019). Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis. Revista de Chimie, 70(9), 3216-3219. https://doi.org/10.37358/RC.19.9.7520

Harvard
Filip, A., Badulescu, O.V., Sirbu, P.D., Cojocaru, E., Filip, N., Puha, G., Trandafir, L., Iancu, C., Trandafirescu, M.F., Alexa, O. (2019). 'Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis', Revista de Chimie, 70(9), pp. 3216-3219. https://doi.org/10.37358/RC.19.9.7520

IEEE
A. Filip, O.V. Badulescu, P.D. Sirbu, E. Cojocaru, N. Filip, G. Puha, L. Trandafir, C. Iancu, M.F. Trandafirescu, O. Alexa, "Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis". Revista de Chimie, vol. 70, no. 9, pp. 3216-3219, 2019. [online]. https://doi.org/10.37358/RC.19.9.7520

Text
Alexandru Filip, Oana Viola Badulescu, Paul Dan Sirbu, Elena Cojocaru, Nina Filip, Gabriela Puha, Laura Trandafir, Cristina Iancu, Mioara Florentina Trandafirescu, Ovidiu Alexa,
Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis,
Revista de Chimie,
Volume 70, Issue 9,
2019,
Pages 3216-3219,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.9.7520.
(https://revistadechimie.ro/Articles.asp?ID=7520)
Keywords: fragility fracture; homocysteine; osteoporosis; oxidative stress

RIS
TY - JOUR
T1 - Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis
A1 - Filip, Alexandru
A2 - Badulescu, Oana Viola
A3 - Sirbu, Paul Dan
A4 - Cojocaru, Elena
A5 - Filip, Nina
A6 - Puha, Gabriela
A7 - Trandafir, Laura
A8 - Iancu, Cristina
A9 - Trandafirescu, Mioara Florentina
A10 - Alexa, Ovidiu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 9
SP - 3216
EP - 3219
UR - https://doi.org/10.37358/RC.19.9.7520
KW - fragility fracture
KW - homocysteine
KW - osteoporosis
KW - oxidative stress
ER -

BibTex
@article{RevCh2019P3216,
author = {Filip Alexandru and Badulescu Oana Viola and Sirbu Paul Dan and Cojocaru Elena and Filip Nina and Puha Gabriela and Trandafir Laura and Iancu Cristina and Trandafirescu Mioara Florentina and Alexa Ovidiu},
title = {Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis},
journal = {Revista de Chimie},
volume = {70},
number = {9},
pages = {3216-3219},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.9.7520},
url = {https://revistadechimie.ro/Articles.asp?ID=7520}
}

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