Andreea Loredana Golli, Floarea Mimi Nitu, Maria Balasoiu, Roxana Maria Nemes, Sorin Ioan Tudorache, Beatrice Mahler Boca, Mihai Olteanu
Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit
Abstract:
The emergence of multidrug-resistant (MDR) pathogens, especially for intensive care unit (ICU) patients is a serious threat to public health. To determine the frequency and antibiotic resistance pattern of bacterial pathogens isolated from tracheal aspirates of the patients admitted in ICU. The retrospective study included endotracheal aspirates from 734 patients admitted to the ICU, from January to December 2017. The analysis of the resistance patterns for the action of the appropriate antibiotics was performed using Vitek 2 Compact system and diffusion method. A total of 985 bacterial isolates were obtained, of which 227 strains of Klebsiella spp. (23.04%), followed by Nonfermenting Gram negative bacilli, other than Pseudomonas and Acinetobacter (NFB) (170- 17.25%), MRSA (134- 13.60%). Isolation rates indicates a higher value for male patients and elderly patients (over 65 years), statistically significant. High rates of MDR were found for Klebsiella spp. (70.04%) and Pseudomonas aeruginosa (66.25%) while almost all of the isolated NFB strains were MDR (98.82%). The study revealed high rates of MDR pathogens in the majority of ICU isolates which may be due to unnecessary use of higher generations of antibiotics, use of mechanical devices, age, comorbidities, and can determine a higher rate of morbidity and mortality among these patients.
Keywords: multidrug resistance (MDR); intensive care unit; endotracheal aspirates
Cite this article as: GOLLI, A.L., NITU, F.M., BALASOIU, M., NEMES, R.M., TUDORACHE, S.I., BOCA, B.M., OLTEANU, M., Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit, Rev. Chim., 70(9), 2019, 3299-3304.
Vancouver Golli AL, Nitu FM, Balasoiu M, Nemes RM, Tudorache SI, Boca BM, Olteanu M. Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit. Rev. Chim.[internet]. 2019 Sep;70(9):3299-3304. Available from: https://doi.org/10.37358/RC.19.9.7538
APA 6th edition Golli, A.L., Nitu, F.M., Balasoiu, M., Nemes, R.M., Tudorache, S.I., Boca, B.M. & Olteanu, M. (2019). Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit. Revista de Chimie, 70(9), 3299-3304. https://doi.org/10.37358/RC.19.9.7538
Harvard Golli, A.L., Nitu, F.M., Balasoiu, M., Nemes, R.M., Tudorache, S.I., Boca, B.M., Olteanu, M. (2019). 'Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit', Revista de Chimie, 70(9), pp. 3299-3304. https://doi.org/10.37358/RC.19.9.7538
IEEE A.L. Golli, F.M. Nitu, M. Balasoiu, R.M. Nemes, S.I. Tudorache, B.M. Boca, M. Olteanu, "Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit". Revista de Chimie, vol. 70, no. 9, pp. 3299-3304, 2019. [online]. https://doi.org/10.37358/RC.19.9.7538
Text Andreea Loredana Golli, Floarea Mimi Nitu, Maria Balasoiu, Roxana Maria Nemes, Sorin Ioan Tudorache, Beatrice Mahler Boca, Mihai Olteanu, Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit, Revista de Chimie, Volume 70, Issue 9, 2019, Pages 3299-3304, ISSN 2668-8212, https://doi.org/10.37358/RC.19.9.7538. (https://revistadechimie.ro/Articles.asp?ID=7538) Keywords: multidrug resistance (MDR); intensive care unit; endotracheal aspirates
RIS TY - JOUR T1 - Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit A1 - Golli, Andreea Loredana A2 - Nitu, Floarea Mimi A3 - Balasoiu, Maria A4 - Nemes, Roxana Maria A5 - Tudorache, Sorin Ioan A6 - Boca, Beatrice Mahler A7 - Olteanu, Mihai JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2019 VL - 70 IS - 9 SP - 3299 EP - 3304 UR - https://doi.org/10.37358/RC.19.9.7538 KW - multidrug resistance (MDR) KW - intensive care unit KW - endotracheal aspirates ER -
BibTex @article{RevCh2019P3299, author = {Golli Andreea Loredana and Nitu Floarea Mimi and Balasoiu Maria and Nemes Roxana Maria and Tudorache Sorin Ioan and Boca Beatrice Mahler and Olteanu Mihai}, title = {Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit}, journal = {Revista de Chimie}, volume = {70}, number = {9}, pages = {3299-3304}, year = {2019}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.19.9.7538}, url = {https://revistadechimie.ro/Articles.asp?ID=7538} }