Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease

Ardeleanu, Iuliana; Floria, Mariana; Badulescu, Oana Viola; Bojan, Iris Bararu; Vladeanu, Maria; Anghel, Larisa; Tanase, Ana; Macovei, Liviu; Statescu, Cristian; Ciocoiu, Manuela; Sirbu, Paul Dan; Georgescu, Catalina Arsenescu

Iuliana Ardeleanu, Mariana Floria, Oana Viola Badulescu, Iris Bararu Bojan, Maria Vladeanu, Larisa Anghel, Ana Tanase, Liviu Macovei, Cristian Statescu, Manuela Ciocoiu, Paul Dan Sirbu, Catalina Arsenescu Georgescu

Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease

Abstract:

The non-valvular AF, beyond the guidelines, include 2 types of patients. We aimed to analyze the clinical and biological profile of patients with non-valvular atrial fibrillation (AF)andhemodynamicsignificantvalvular heart disease. We includedretrospectively 513 patients admitted in our hospitalwithnon-valvular AF, and we divided into:study group(333 patients; 64.9%) andcontrole group(180 patients; 35.1%) hemodynamic significant valvular heart disease. From the studied group 5.5% of patients associated all four valvular heart disease, 26.7% ofpatients associated mitral, aortic and tricuspid regurgitation and 71.9%of patients associated two valvular heart disease: 32.7% with mitral and aortic, 31.4% with mitral and tricuspid, 4.5% with tricuspid and pulmonary, and3.3% withtricuspid and aortic. Dyslipidemia (higher cholesterol and trygliceride levels) was present in 14.5% of patients, statistic significantly more frequently in patients from the control group (11.4% vs 18.3%, P= 0.033). Dyslipidemia showed a significantly higher estimated risk for AF (RR=1.25; IC95%: 0.99-1.56), as well as diabetes mellitus (RR=1.36; IC95%: 1.12-1.64)and coronary heart disease (RR=3.70; IC95%: 1.83-7.46). Therefore patients with non-valvular AF and hemodynamic significant valvular heart disease, beyond the curent guidelines, could has a completely different profile and prognosis.

Keywords:
Atrial Fibrillation; Non-valvular;Valve Disease;Hemodynamicaly Significant;dyslipidemia

Issue: 2019, Volume 70, Issue 9

Pages: 3412-3415

Publication date: 2019/10/15

https://doi.org/10.37358/RC.19.9.7560

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ARDELEANU, I., FLORIA, M., BADULESCU, O.V., BOJAN, I.B., VLADEANU, M., ANGHEL, L., TANASE, A., MACOVEI, L., STATESCU, C., CIOCOIU, M., SIRBU, P.D., GEORGESCU, C.A., Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease, Rev. Chim., 70(9), 2019, 3412-3415.

Vancouver
Ardeleanu I, Floria M, Badulescu OV, Bojan IB, Vladeanu M, Anghel L, Tanase A, Macovei L, Statescu C, Ciocoiu M, Sirbu PD, Georgescu CA. Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease. Rev. Chim.[internet]. 2019 Sep;70(9):3412-3415. Available from: https://doi.org/10.37358/RC.19.9.7560

APA 6th edition
Ardeleanu, I., Floria, M., Badulescu, O.V., Bojan, I.B., Vladeanu, M., Anghel, L.,... Georgescu, C.A. (2019). Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease. Revista de Chimie, 70(9), 3412-3415. https://doi.org/10.37358/RC.19.9.7560

Harvard
Ardeleanu, I., Floria, M., Badulescu, O.V., Bojan, I.B., Vladeanu, M., Anghel, L., Tanase, A., Macovei, L., Statescu, C., Ciocoiu, M., Sirbu, P.D., Georgescu, C.A. (2019). 'Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease', Revista de Chimie, 70(9), pp. 3412-3415. https://doi.org/10.37358/RC.19.9.7560

IEEE
I. Ardeleanu, M. Floria, O.V. Badulescu, I.B. Bojan, M. Vladeanu, L. Anghel, A. Tanase, L. Macovei, C. Statescu, M. Ciocoiu, P.D. Sirbu, C.A. Georgescu, "Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease". Revista de Chimie, vol. 70, no. 9, pp. 3412-3415, 2019. [online]. https://doi.org/10.37358/RC.19.9.7560

Text
Iuliana Ardeleanu, Mariana Floria, Oana Viola Badulescu, Iris Bararu Bojan, Maria Vladeanu, Larisa Anghel, Ana Tanase, Liviu Macovei, Cristian Statescu, Manuela Ciocoiu, Paul Dan Sirbu, Catalina Arsenescu Georgescu,
Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease,
Revista de Chimie,
Volume 70, Issue 9,
2019,
Pages 3412-3415,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.9.7560.
(https://revistadechimie.ro/Articles.asp?ID=7560)
Keywords: Atrial Fibrillation; Non-valvular;Valve Disease;Hemodynamicaly Significant;dyslipidemia

RIS
TY - JOUR
T1 - Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease
A1 - Ardeleanu, Iuliana
A2 - Floria, Mariana
A3 - Badulescu, Oana Viola
A4 - Bojan, Iris Bararu
A5 - Vladeanu, Maria
A6 - Anghel, Larisa
A7 - Tanase, Ana
A8 - Macovei, Liviu
A9 - Statescu, Cristian
A10 - Ciocoiu, Manuela
A11 - Sirbu, Paul Dan
A12 - Georgescu, Catalina Arsenescu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 9
SP - 3412
EP - 3415
UR - https://doi.org/10.37358/RC.19.9.7560
KW - Atrial Fibrillation; Non-valvular;Valve Disease;Hemodynamicaly Significant;dyslipidemia
ER -

BibTex
@article{RevCh2019P3412,
author = {Ardeleanu Iuliana and Floria Mariana and Badulescu Oana Viola and Bojan Iris Bararu and Vladeanu Maria and Anghel Larisa and Tanase Ana and Macovei Liviu and Statescu Cristian and Ciocoiu Manuela and Sirbu Paul Dan and Georgescu Catalina Arsenescu},
title = {Clinical and Biological Profile of Patients with Non-Valvular Atrial Fibrillation and Hemodynamic Significant Valvular Heart Disease},
journal = {Revista de Chimie},
volume = {70},
number = {9},
pages = {3412-3415},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.9.7560},
url = {https://revistadechimie.ro/Articles.asp?ID=7560}
}

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