Biochemical Markers of Sudden Cardiac Death

Neagu, Marius; Fulga, Ana; Neagu, Anca-Iulia; Bulgaru-Iliescu, Diana; Moraru, Monica; Ciubara, Ana Maria; Fulga, Iuliu

Marius Neagu, Ana Fulga, Anca-Iulia Neagu, Diana Bulgaru-Iliescu, Monica Moraru, Ana Maria Ciubara, Iuliu Fulga

Biochemical Markers of Sudden Cardiac Death

Abstract:

The possible use of biochemical markers in the postmortem diagnosis of sudden cardiac deaths is well known in the forensic setting, though several issues have limited its widespread adoption. The aim of the present study was to describe the discovery of cardiac troponin I (cTnI), myoglobin (MYO) and creatinine kinase MB (CK-MB) in femoral whole blood (FWB), pericardial fluid (PF) and vitreous humor (VH) samples, that were collected post-mortem, in various cases of death related to ischemic heart disease, using the rapid diagnostic test 'Cardiac Markers Combo Rapid Test Device'. The authors conducted a prospective study in which they analyzed a total of 100 autopsies performed at the Legal Medicine Clinical Service of Galați County. The results of the present study showed that cardiac markers can be determined using rapid diagnostic tests for blood from the femoral vein and pericardial fluid, but not for the vitreous humor. Using postmortem biochemical markers of myocardial ischaemia requires caution and flexibility, so that the forensic pathologist has to take into consideration, when interpreting the results, both the postmortem interval, and the type of biological sample.

Keywords:
sudden death; cardiac; markers; troponin; forensic pathology

Issue: 2019, Volume 70, Issue 12

Pages: 4283-4286

Publication date: 2020/1/20

https://doi.org/10.37358/RC.19.12.7746

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
NEAGU, M., FULGA, A., NEAGU, A., BULGARU-ILIESCU, D., MORARU, M., CIUBARA, A.M., FULGA, I., Biochemical Markers of Sudden Cardiac Death, Rev. Chim., 70(12), 2019, 4283-4286.

Vancouver
Neagu M, Fulga A, Neagu A, Bulgaru-Iliescu D, Moraru M, Ciubara AM, Fulga I. Biochemical Markers of Sudden Cardiac Death. Rev. Chim.[internet]. 2019 Dec;70(12):4283-4286. Available from: https://doi.org/10.37358/RC.19.12.7746

APA 6th edition
Neagu, M., Fulga, A., Neagu, A., Bulgaru-Iliescu, D., Moraru, M., Ciubara, A.M. & Fulga, I. (2019). Biochemical Markers of Sudden Cardiac Death. Revista de Chimie, 70(12), 4283-4286. https://doi.org/10.37358/RC.19.12.7746

Harvard
Neagu, M., Fulga, A., Neagu, A., Bulgaru-Iliescu, D., Moraru, M., Ciubara, A.M., Fulga, I. (2019). 'Biochemical Markers of Sudden Cardiac Death', Revista de Chimie, 70(12), pp. 4283-4286. https://doi.org/10.37358/RC.19.12.7746

IEEE
M. Neagu, A. Fulga, A. Neagu, D. Bulgaru-Iliescu, M. Moraru, A.M. Ciubara, I. Fulga, "Biochemical Markers of Sudden Cardiac Death". Revista de Chimie, vol. 70, no. 12, pp. 4283-4286, 2019. [online]. https://doi.org/10.37358/RC.19.12.7746

Text
Marius Neagu, Ana Fulga, Anca-Iulia Neagu, Diana Bulgaru-Iliescu, Monica Moraru, Ana Maria Ciubara, Iuliu Fulga,
Biochemical Markers of Sudden Cardiac Death,
Revista de Chimie,
Volume 70, Issue 12,
2019,
Pages 4283-4286,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.12.7746.
(https://revistadechimie.ro/Articles.asp?ID=7746)
Keywords: sudden death; cardiac; markers; troponin; forensic pathology

RIS
TY - JOUR
T1 - Biochemical Markers of Sudden Cardiac Death
A1 - Neagu, Marius
A2 - Fulga, Ana
A3 - Neagu, Anca-Iulia
A4 - Bulgaru-Iliescu, Diana
A5 - Moraru, Monica
A6 - Ciubara, Ana Maria
A7 - Fulga, Iuliu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 12
SP - 4283
EP - 4286
UR - https://doi.org/10.37358/RC.19.12.7746
KW - sudden death
KW - cardiac
KW - markers
KW - troponin
KW - forensic pathology
ER -

BibTex
@article{RevCh2019P4283,
author = {Neagu Marius and Fulga Ana and Neagu Anca-Iulia and Bulgaru-Iliescu Diana and Moraru Monica and Ciubara Ana Maria and Fulga Iuliu},
title = {Biochemical Markers of Sudden Cardiac Death},
journal = {Revista de Chimie},
volume = {70},
number = {12},
pages = {4283-4286},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.12.7746},
url = {https://revistadechimie.ro/Articles.asp?ID=7746}
}

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