Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile

Golli, Andreea-Loredana; NiȚu, Floarea Mimi; BălăȘoiu, Maria; Popa, Simona Georgiana; Fortofoiu, Maria; NemeȘ, Roxana Maria; Tudorache, Sorin Ioan; NemeȘ, Alexandra Floriana; Olteanu, Mihai

Andreea-Loredana Golli, Floarea Mimi NiȚu, Maria BălăȘoiu, Simona Georgiana Popa, Maria Fortofoiu, Roxana Maria NemeȘ, Sorin Ioan Tudorache, Alexandra Floriana NemeȘ, Mihai Olteanu

Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile

Abstract:

Cancer is the second leading cause of death in Romania and worldwide. Cancer patients are at increasing risk of acquiring bacterial infection with multi-resistant germs, including multidrug-resistant (MDR) strains of Gram-negative bacteria involved in nosocomial infection. Romania is one of the South-Eastern European countries with one of the highest prevalence rates of MDR pathogens. To determine the resistance pattern of bacterial profile and antibiotic resistance pattern in cancer patients admitted at the County Emergency Clinical Hospital Craiova, Romania. A retrospective study of bacterial pathogens was carried out on 90 adult cancer patients admitted from January to December 2018. The analysis of the resistance patterns for the action of the appropriate antibiotics was performed using Vitek 2 Compact system and diffusion method. In this study there were analysed 92 samples from 90 oncological patients (37-86 years). A total of 157 bacterial isolates were obtained, of which 37 strains of Staphylococcus aureus (23.56%), followed by Streptococcus pneumoniae (23- 14.64%), Klebsiella spp. and Escherichia coli (22 - 14,01%). The most common isolates were from respiratory tract (86 isolates - 54.77%). High rates of MDR were found for E. coli (63.63%), MRSA (61,11%) and Klebsiella spp. (54,54%), while one third of the isolated strains of Pseudomonas aeruginosa, Acinetobacter spp. and Proteus spp. were MDR. The findings of this study may be the basis for further more extensive studies highlighting the germs involved in the infectious pathology of cancer patients, in order to determine the antimicrobial resistance and to improve the methods of prophylaxis and treatment.

Keywords:
multidrug resistance (MDR); cancer patients; bacterial pathogen

Issue: 2019, Volume 70, Issue 12

Pages: 4287-4294

Publication date: 2020/1/20

https://doi.org/10.37358/RC.19.12.7747

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GOLLI, A., NIȚU, F.M., BĂLĂȘOIU, M., POPA, S.G., FORTOFOIU, M., NEMEȘ, R.M., TUDORACHE, S.I., NEMEȘ, A.F., OLTEANU, M., Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile, Rev. Chim., 70(12), 2019, 4287-4294.

Vancouver
Golli A, NiȚu FM, BălăȘoiu M, Popa SG, Fortofoiu M, NemeȘ RM, Tudorache SI, NemeȘ AF, Olteanu M. Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile. Rev. Chim.[internet]. 2019 Dec;70(12):4287-4294. Available from: https://doi.org/10.37358/RC.19.12.7747

APA 6th edition
Golli, A., NiȚu, F.M., BălăȘoiu, M., Popa, S.G., Fortofoiu, M., NemeȘ, R.M.,... Olteanu, M. (2019). Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile. Revista de Chimie, 70(12), 4287-4294. https://doi.org/10.37358/RC.19.12.7747

Harvard
Golli, A., NiȚu, F.M., BălăȘoiu, M., Popa, S.G., Fortofoiu, M., NemeȘ, R.M., Tudorache, S.I., NemeȘ, A.F., Olteanu, M. (2019). 'Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile', Revista de Chimie, 70(12), pp. 4287-4294. https://doi.org/10.37358/RC.19.12.7747

IEEE
A. Golli, F.M. NiȚu, M. BălăȘoiu, S.G. Popa, M. Fortofoiu, R.M. NemeȘ, S.I. Tudorache, A.F. NemeȘ, M. Olteanu, "Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile". Revista de Chimie, vol. 70, no. 12, pp. 4287-4294, 2019. [online]. https://doi.org/10.37358/RC.19.12.7747

Text
Andreea-Loredana Golli, Floarea Mimi NiȚu, Maria BălăȘoiu, Simona Georgiana Popa, Maria Fortofoiu, Roxana Maria NemeȘ, Sorin Ioan Tudorache, Alexandra Floriana NemeȘ, Mihai Olteanu,
Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile,
Revista de Chimie,
Volume 70, Issue 12,
2019,
Pages 4287-4294,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.12.7747.
(https://revistadechimie.ro/Articles.asp?ID=7747)
Keywords: multidrug resistance (MDR); cancer patients; bacterial pathogen

RIS
TY - JOUR
T1 - Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile
A1 - Golli, Andreea-Loredana
A2 - NiȚu, Floarea Mimi
A3 - BălăȘoiu, Maria
A4 - Popa, Simona Georgiana
A5 - Fortofoiu, Maria
A6 - NemeȘ, Roxana Maria
A7 - Tudorache, Sorin Ioan
A8 - NemeȘ, Alexandra Floriana
A9 - Olteanu, Mihai
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 12
SP - 4287
EP - 4294
UR - https://doi.org/10.37358/RC.19.12.7747
KW - multidrug resistance (MDR)
KW - cancer patients
KW - bacterial pathogen
ER -

BibTex
@article{RevCh2019P4287,
author = {Golli Andreea-Loredana and NiȚu Floarea Mimi and BălăȘoiu Maria and Popa Simona Georgiana and Fortofoiu Maria and NemeȘ Roxana Maria and Tudorache Sorin Ioan and NemeȘ Alexandra Floriana and Olteanu Mihai},
title = {Distribution of Pathogens Involved in Infections in Oncological Patients and their Antibiotic Resistance Profile},
journal = {Revista de Chimie},
volume = {70},
number = {12},
pages = {4287-4294},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.12.7747},
url = {https://revistadechimie.ro/Articles.asp?ID=7747}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)