Simona Carabineanu, Dana Stoian, Flavius Olaru, Laurentiu Sima, Alexandru Blidisel, Florin Birsasteanu, Sorin Motoi, Adrian Carabineanu, Marius Craina, Marioara Boia, Dan Navolan
Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies
Abstract:
Autoimmune thyroiditis is the most frequent autoimmune disease. We analyzed the association between the presence and value of titer of anti-thyroid antibodies (atbs) and spontaneous abortion (SA). Moreover, we analyzed the association between TSH values and the presence of anti-thyroids atbs. We tested anti-TPO and anti-TG atbs in 257 women: 85 probands, 87 pregnant women with normal pregnancy outcome, and 85 with SA. We tested TSH in 87 pregnant women with normal pregnancy outcome. No significant difference was found between the prevalence of cases with positive anti-TPO and anti-TG atbs in women with normal pregnancy outcome vs. SA patients. In women with positive atbs titer, anti-TPO and anti-TG values were higher in SA group compared with normal pregnancy outcome group. A significant threshold was reached only for anti-TG atbs. TSH values were higher in pregnant women with positive anti-TPO and anti-TG values compared with those with a negative atbs titer. In pregnant women with positive anti-thyroid atbs titers, spontaneous abortion group patients have higher anti-TG titers than women with normal pregnancy outcome. TSH values are higher in the group of patients with positive anti-TPO and anti-TG atbs titers compared with the group of patients with negative anti-TPO and anti-TG values.
Cite this article as: CARABINEANU, S., STOIAN, D., OLARU, F., SIMA, L., BLIDISEL, A., BIRSASTEANU, F., MOTOI, S., CARABINEANU, A., CRAINA, M., BOIA, M., NAVOLAN, D., Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies, Rev. Chim., 70(12), 2019, 4326-4331.
Vancouver Carabineanu S, Stoian D, Olaru F, Sima L, Blidisel A, Birsasteanu F, Motoi S, Carabineanu A, Craina M, Boia M, Navolan D. Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies. Rev. Chim.[internet]. 2019 Dec;70(12):4326-4331. Available from: https://doi.org/10.37358/RC.19.12.7753
APA 6th edition Carabineanu, S., Stoian, D., Olaru, F., Sima, L., Blidisel, A., Birsasteanu, F.,... Navolan, D. (2019). Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies. Revista de Chimie, 70(12), 4326-4331. https://doi.org/10.37358/RC.19.12.7753
Harvard Carabineanu, S., Stoian, D., Olaru, F., Sima, L., Blidisel, A., Birsasteanu, F., Motoi, S., Carabineanu, A., Craina, M., Boia, M., Navolan, D. (2019). 'Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies', Revista de Chimie, 70(12), pp. 4326-4331. https://doi.org/10.37358/RC.19.12.7753
IEEE S. Carabineanu, D. Stoian, F. Olaru, L. Sima, A. Blidisel, F. Birsasteanu, S. Motoi, A. Carabineanu, M. Craina, M. Boia, D. Navolan, "Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies". Revista de Chimie, vol. 70, no. 12, pp. 4326-4331, 2019. [online]. https://doi.org/10.37358/RC.19.12.7753
Text Simona Carabineanu, Dana Stoian, Flavius Olaru, Laurentiu Sima, Alexandru Blidisel, Florin Birsasteanu, Sorin Motoi, Adrian Carabineanu, Marius Craina, Marioara Boia, Dan Navolan, Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies, Revista de Chimie, Volume 70, Issue 12, 2019, Pages 4326-4331, ISSN 2668-8212, https://doi.org/10.37358/RC.19.12.7753. (https://revistadechimie.ro/Articles.asp?ID=7753) Keywords: Anti-TPO; anti-TG; pregnancy outcome; spontaneous abortion; TSH
RIS TY - JOUR T1 - Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies A1 - Carabineanu, Simona A2 - Stoian, Dana A3 - Olaru, Flavius A4 - Sima, Laurentiu A5 - Blidisel, Alexandru A6 - Birsasteanu, Florin A7 - Motoi, Sorin A8 - Carabineanu, Adrian A9 - Craina, Marius A10 - Boia, Marioara A11 - Navolan, Dan JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2019 VL - 70 IS - 12 SP - 4326 EP - 4331 UR - https://doi.org/10.37358/RC.19.12.7753 KW - Anti-TPO KW - anti-TG KW - pregnancy outcome KW - spontaneous abortion KW - TSH ER -
BibTex @article{RevCh2019P4326, author = {Carabineanu Simona and Stoian Dana and Olaru Flavius and Sima Laurentiu and Blidisel Alexandru and Birsasteanu Florin and Motoi Sorin and Carabineanu Adrian and Craina Marius and Boia Marioara and Navolan Dan}, title = {Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies}, journal = {Revista de Chimie}, volume = {70}, number = {12}, pages = {4326-4331}, year = {2019}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.19.12.7753}, url = {https://revistadechimie.ro/Articles.asp?ID=7753} }