Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies

Carabineanu, Simona; Stoian, Dana; Olaru, Flavius; Sima, Laurentiu; Blidisel, Alexandru; Birsasteanu, Florin; Motoi, Sorin; Carabineanu, Adrian; Craina, Marius; Boia, Marioara; Navolan, Dan

Simona Carabineanu, Dana Stoian, Flavius Olaru, Laurentiu Sima, Alexandru Blidisel, Florin Birsasteanu, Sorin Motoi, Adrian Carabineanu, Marius Craina, Marioara Boia, Dan Navolan

Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies

Abstract:

Autoimmune thyroiditis is the most frequent autoimmune disease. We analyzed the association between the presence and value of titer of anti-thyroid antibodies (atbs) and spontaneous abortion (SA). Moreover, we analyzed the association between TSH values and the presence of anti-thyroids atbs. We tested anti-TPO and anti-TG atbs in 257 women: 85 probands, 87 pregnant women with normal pregnancy outcome, and 85 with SA. We tested TSH in 87 pregnant women with normal pregnancy outcome. No significant difference was found between the prevalence of cases with positive anti-TPO and anti-TG atbs in women with normal pregnancy outcome vs. SA patients. In women with positive atbs titer, anti-TPO and anti-TG values were higher in SA group compared with normal pregnancy outcome group. A significant threshold was reached only for anti-TG atbs. TSH values were higher in pregnant women with positive anti-TPO and anti-TG values compared with those with a negative atbs titer. In pregnant women with positive anti-thyroid atbs titers, spontaneous abortion group patients have higher anti-TG titers than women with normal pregnancy outcome. TSH values are higher in the group of patients with positive anti-TPO and anti-TG atbs titers compared with the group of patients with negative anti-TPO and anti-TG values.

Keywords:
Anti-TPO; anti-TG; pregnancy outcome; spontaneous abortion; TSH

Issue: 2019, Volume 70, Issue 12

Pages: 4326-4331

Publication date: 2020/1/20

https://doi.org/10.37358/RC.19.12.7753

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CARABINEANU, S., STOIAN, D., OLARU, F., SIMA, L., BLIDISEL, A., BIRSASTEANU, F., MOTOI, S., CARABINEANU, A., CRAINA, M., BOIA, M., NAVOLAN, D., Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies, Rev. Chim., 70(12), 2019, 4326-4331.

Vancouver
Carabineanu S, Stoian D, Olaru F, Sima L, Blidisel A, Birsasteanu F, Motoi S, Carabineanu A, Craina M, Boia M, Navolan D. Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies. Rev. Chim.[internet]. 2019 Dec;70(12):4326-4331. Available from: https://doi.org/10.37358/RC.19.12.7753

APA 6th edition
Carabineanu, S., Stoian, D., Olaru, F., Sima, L., Blidisel, A., Birsasteanu, F.,... Navolan, D. (2019). Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies. Revista de Chimie, 70(12), 4326-4331. https://doi.org/10.37358/RC.19.12.7753

Harvard
Carabineanu, S., Stoian, D., Olaru, F., Sima, L., Blidisel, A., Birsasteanu, F., Motoi, S., Carabineanu, A., Craina, M., Boia, M., Navolan, D. (2019). 'Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies', Revista de Chimie, 70(12), pp. 4326-4331. https://doi.org/10.37358/RC.19.12.7753

IEEE
S. Carabineanu, D. Stoian, F. Olaru, L. Sima, A. Blidisel, F. Birsasteanu, S. Motoi, A. Carabineanu, M. Craina, M. Boia, D. Navolan, "Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies". Revista de Chimie, vol. 70, no. 12, pp. 4326-4331, 2019. [online]. https://doi.org/10.37358/RC.19.12.7753

Text
Simona Carabineanu, Dana Stoian, Flavius Olaru, Laurentiu Sima, Alexandru Blidisel, Florin Birsasteanu, Sorin Motoi, Adrian Carabineanu, Marius Craina, Marioara Boia, Dan Navolan,
Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies,
Revista de Chimie,
Volume 70, Issue 12,
2019,
Pages 4326-4331,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.12.7753.
(https://revistadechimie.ro/Articles.asp?ID=7753)
Keywords: Anti-TPO; anti-TG; pregnancy outcome; spontaneous abortion; TSH

RIS
TY - JOUR
T1 - Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies
A1 - Carabineanu, Simona
A2 - Stoian, Dana
A3 - Olaru, Flavius
A4 - Sima, Laurentiu
A5 - Blidisel, Alexandru
A6 - Birsasteanu, Florin
A7 - Motoi, Sorin
A8 - Carabineanu, Adrian
A9 - Craina, Marius
A10 - Boia, Marioara
A11 - Navolan, Dan
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 12
SP - 4326
EP - 4331
UR - https://doi.org/10.37358/RC.19.12.7753
KW - Anti-TPO
KW - anti-TG
KW - pregnancy outcome
KW - spontaneous abortion
KW - TSH
ER -

BibTex
@article{RevCh2019P4326,
author = {Carabineanu Simona and Stoian Dana and Olaru Flavius and Sima Laurentiu and Blidisel Alexandru and Birsasteanu Florin and Motoi Sorin and Carabineanu Adrian and Craina Marius and Boia Marioara and Navolan Dan},
title = {Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies},
journal = {Revista de Chimie},
volume = {70},
number = {12},
pages = {4326-4331},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.12.7753},
url = {https://revistadechimie.ro/Articles.asp?ID=7753}
}

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