Uric Acid in Cardiovascular Diseases: A Factor or an Incident?

Anghel, Lucretia; Beznea, Adrian; Neagu, Anca-Iulia; Topor, Gabi; Onisor, Cristian; Fotea, Silvia

Lucretia Anghel, Adrian Beznea, Anca-Iulia Neagu, Gabi Topor, Cristian Onisor, Silvia Fotea

Uric Acid in Cardiovascular Diseases: A Factor or an Incident?

Abstract:

The pathophysiological involvement of uric acid in cardiovascular disease has been intensively addressed in the last decades by the medical community. The tendencies to elucidate its role in cardiac events have been carried out in numerous researches with controversial results. In an attempt to understand this phenomenon, the existence of a paradox is admited, according to which uric acid behaves as an antioxidant, capturing reactive oxygen species, and in the context of an existing cardiac pathology, manifests a precipitating oxidative effect of circulating lipids, there being also present. inflammatory substrate. The involvement of the target organs in hypertension, along with other factors such as hyperlipidemia, obesity, pathologies of the valvular apparatus, contributes to the appearance of hyperuricemia of excretory cause. The ability of xanthine oxidoreductase to produce reactive oxygen species that contribute to the occurrence of oxidative stress and endothelial dysfunction has redirected our visions to a more complex approach to ischemic heart disease. And the use of xanthine oxidoreductase inhibitors in cardiovascular disease in patients with hyperuricemia has allowed to appreciate real benefits in improving renal function and preventing atherosclerosis.

Keywords:
uric acid; cardiovascular disease; factor

Issue: 2019, Volume 70, Issue 12

Pages: 4442-4444

Publication date: 2020/1/20

https://doi.org/10.37358/RC.19.12.7773

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ANGHEL, L., BEZNEA, A., NEAGU, A., TOPOR, G., ONISOR, C., FOTEA, S., Uric Acid in Cardiovascular Diseases: A Factor or an Incident?, Rev. Chim., 70(12), 2019, 4442-4444.

Vancouver
Anghel L, Beznea A, Neagu A, Topor G, Onisor C, Fotea S. Uric Acid in Cardiovascular Diseases: A Factor or an Incident?. Rev. Chim.[internet]. 2019 Dec;70(12):4442-4444. Available from: https://doi.org/10.37358/RC.19.12.7773

APA 6th edition
Anghel, L., Beznea, A., Neagu, A., Topor, G., Onisor, C. & Fotea, S. (2019). Uric Acid in Cardiovascular Diseases: A Factor or an Incident?. Revista de Chimie, 70(12), 4442-4444. https://doi.org/10.37358/RC.19.12.7773

Harvard
Anghel, L., Beznea, A., Neagu, A., Topor, G., Onisor, C., Fotea, S. (2019). 'Uric Acid in Cardiovascular Diseases: A Factor or an Incident?', Revista de Chimie, 70(12), pp. 4442-4444. https://doi.org/10.37358/RC.19.12.7773

IEEE
L. Anghel, A. Beznea, A. Neagu, G. Topor, C. Onisor, S. Fotea, "Uric Acid in Cardiovascular Diseases: A Factor or an Incident?". Revista de Chimie, vol. 70, no. 12, pp. 4442-4444, 2019. [online]. https://doi.org/10.37358/RC.19.12.7773

Text
Lucretia Anghel, Adrian Beznea, Anca-Iulia Neagu, Gabi Topor, Cristian Onisor, Silvia Fotea,
Uric Acid in Cardiovascular Diseases: A Factor or an Incident?,
Revista de Chimie,
Volume 70, Issue 12,
2019,
Pages 4442-4444,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.12.7773.
(https://revistadechimie.ro/Articles.asp?ID=7773)
Keywords: uric acid; cardiovascular disease; factor

RIS
TY - JOUR
T1 - Uric Acid in Cardiovascular Diseases: A Factor or an Incident?
A1 - Anghel, Lucretia
A2 - Beznea, Adrian
A3 - Neagu, Anca-Iulia
A4 - Topor, Gabi
A5 - Onisor, Cristian
A6 - Fotea, Silvia
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 12
SP - 4442
EP - 4444
UR - https://doi.org/10.37358/RC.19.12.7773
KW - uric acid
KW - cardiovascular disease
KW - factor
ER -

BibTex
@article{RevCh2019P4442,
author = {Anghel Lucretia and Beznea Adrian and Neagu Anca-Iulia and Topor Gabi and Onisor Cristian and Fotea Silvia},
title = {Uric Acid in Cardiovascular Diseases: A Factor or an Incident?},
journal = {Revista de Chimie},
volume = {70},
number = {12},
pages = {4442-4444},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.12.7773},
url = {https://revistadechimie.ro/Articles.asp?ID=7773}
}

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