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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 12, 4445-4449

https://doi.org/10.37358/RC.19.12.7774

Georgeta Zegan, Mihaela Moscu, Eduard Radu Cernei, Elena Mihaela Carausu, Alina Sodor-Botezatu

Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens

Abstract:

Last few years antibiotics resistance known a major problem that concerns the specialists in the dentistry field due to the improper usage of anti-infectious drugs. Administration of third generation quinolones, levofloxacin (Lev), in dental practice is preferred since has few nonhazardous adverse effects, is used once daily and can be successfully applied as intra-pocket films.This study investigated the possibility of preparing levofloxacin loaded layered double hydroxides nanoparticles in order to enhance antibiotic efficacy against oral pathogens. The nanoparticles obtained under optimal conditions were physico-chemically analyzed and intercalation efficiency was tested. The results of this work revealed that the use of these nanoparticles type levofloxacin loaded layered double hydroxides has the major advantage of prolonged release of the drug, thus allowing an increase of the period between administration and the diminution of side effects of the antibiotic. Further researches should focus on biocompatible properties and antibacterial effect as these nanomaterials supposed to be a sustainable drug delivery system.
Keywords:
nanoparticles; drug carriers; antibacterial properties; public health dentistry; oral infections.

Issue: 2019, Volume 70, Issue 12
Pages: 4445-4449
Publication date: 20/01/2020
https://doi.org/10.37358/RC.19.12.7774
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
ZEGAN, G., MOSCU, M., CERNEI, E.R., CARAUSU, E.M., SODOR-BOTEZATU, A., Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens, Rev. Chim., 70(12), 2019, 4445-4449.

Vancouver
Zegan G, Moscu M, Cernei ER, Carausu EM, Sodor-Botezatu A. Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens. Rev. Chim.[internet]. 2019 Dec;70(12):4445-4449. Available from: https://doi.org/10.37358/RC.19.12.7774


APA 6th edition
Zegan, G., Moscu, M., Cernei, E.R., Carausu, E.M. & Sodor-Botezatu, A. (2019). Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens. Revista de Chimie, 70(12), 4445-4449. https://doi.org/10.37358/RC.19.12.7774


Harvard
Zegan, G., Moscu, M., Cernei, E.R., Carausu, E.M., Sodor-Botezatu, A. (2019). 'Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens', Revista de Chimie, 70(12), pp. 4445-4449. https://doi.org/10.37358/RC.19.12.7774


IEEE
G. Zegan, M. Moscu, E.R. Cernei, E.M. Carausu, A. Sodor-Botezatu, "Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens". Revista de Chimie, vol. 70, no. 12, pp. 4445-4449, 2019. [online]. https://doi.org/10.37358/RC.19.12.7774


Text
Georgeta Zegan, Mihaela Moscu, Eduard Radu Cernei, Elena Mihaela Carausu, Alina Sodor-Botezatu,
Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens,
Revista de Chimie,
Volume 70, Issue 12,
2019,
Pages 4445-4449,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.12.7774.
(https://revistadechimie.ro/Articles.asp?ID=7774)
Keywords: nanoparticles; drug carriers; antibacterial properties; public health dentistry; oral infections.


RIS
TY - JOUR
T1 - Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens
A1 - Zegan, Georgeta
A2 - Moscu, Mihaela
A3 - Cernei, Eduard Radu
A4 - Carausu, Elena Mihaela
A5 - Sodor-Botezatu, Alina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 12
SP - 4445
EP - 4449
UR - https://doi.org/10.37358/RC.19.12.7774
KW - nanoparticles
KW - drug carriers
KW - antibacterial properties
KW - public health dentistry
KW - oral infections.
ER -


BibTex
@article{RevCh2019P4445,
author = {Zegan Georgeta and Moscu Mihaela and Cernei Eduard Radu and Carausu Elena Mihaela and Sodor-Botezatu Alina},
title = {Antimicrobial Effect of Drug Incorporated Nanoparticles Against Oral Pathogens},
journal = {Revista de Chimie},
volume = {70},
number = {12},
pages = {4445-4449},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.12.7774},
url = {https://revistadechimie.ro/Articles.asp?ID=7774}
}
 
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