Influence of Iron Administration on Kidney Serum Parameters

Dronca, Dorel; Pet, Ioan; Stef, Lavinia; Dumitrescu, Gabi; Patruica, Silvia; Nicula, Marioara; Petculescu-Ciochina, Liliana; Popa, Mihaela; Ahmadi, Mirela

Dorel Dronca, Ioan Pet, Lavinia Stef, Gabi Dumitrescu, Silvia Patruica, Marioara Nicula, Liliana Petculescu-Ciochina, Mihaela Popa, Mirela Ahmadi

Influence of Iron Administration on Kidney Serum Parameters

Abstract:

Some minerals are essential nutrients for organisms being necessary in different quantities, but any homeostasis disturbance (deficiency or excess) can lead to various diseases. Iron in the body plays a critical role being directly involved in the respiration process - more precisely O2 and CO2 transportation, and also in beneficial oxidation-reduction processes. But sometimes the iron can also lead to the formation of substances with toxicogenic potential, more precisely to free radicals formed as a result of oxidative stress. In the liver, there is a specialized protein - hepcidin - which is the key regulator of circulating iron in the organism. In several cases of overdose, this protein blocks the iron transportation, binds it to the export channels of ferroportin and finally sends the excess iron to the kidney for urinal excretion. Our experiment tried to evaluate if in case of iron intraperitoneal administration in excess to rabbits, for a short period of time, it influences the serum creatinine, uric acid, and blood urea nitrogen if the rabbits were fed with a special organic diet. The results of the experiment presented a lower concentration of creatinine (with 24.46%), uric acid (with more than 41.48%), and blood urea nitrogen - BUN (6.45%) for experimental rabbits compared to the control group, proving that a well-documented diet influences the accumulation and excretion of excess iron.

Keywords:
iron; creatinine; uric acid; blood urea nitrogen

Issue: 2019, Volume 70, Issue 12

Pages: 4466-4469

Publication date: 2020/1/20

https://doi.org/10.37358/RC.19.12.7777

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
DRONCA, D., PET, I., STEF, L., DUMITRESCU, G., PATRUICA, S., NICULA, M., PETCULESCU-CIOCHINA, L., POPA, M., AHMADI, M., Influence of Iron Administration on Kidney Serum Parameters, Rev. Chim., 70(12), 2019, 4466-4469.

Vancouver
Dronca D, Pet I, Stef L, Dumitrescu G, Patruica S, Nicula M, Petculescu-Ciochina L, Popa M, Ahmadi M. Influence of Iron Administration on Kidney Serum Parameters. Rev. Chim.[internet]. 2019 Dec;70(12):4466-4469. Available from: https://doi.org/10.37358/RC.19.12.7777

APA 6th edition
Dronca, D., Pet, I., Stef, L., Dumitrescu, G., Patruica, S., Nicula, M.,... Ahmadi, M. (2019). Influence of Iron Administration on Kidney Serum Parameters. Revista de Chimie, 70(12), 4466-4469. https://doi.org/10.37358/RC.19.12.7777

Harvard
Dronca, D., Pet, I., Stef, L., Dumitrescu, G., Patruica, S., Nicula, M., Petculescu-Ciochina, L., Popa, M., Ahmadi, M. (2019). 'Influence of Iron Administration on Kidney Serum Parameters', Revista de Chimie, 70(12), pp. 4466-4469. https://doi.org/10.37358/RC.19.12.7777

IEEE
D. Dronca, I. Pet, L. Stef, G. Dumitrescu, S. Patruica, M. Nicula, L. Petculescu-Ciochina, M. Popa, M. Ahmadi, "Influence of Iron Administration on Kidney Serum Parameters". Revista de Chimie, vol. 70, no. 12, pp. 4466-4469, 2019. [online]. https://doi.org/10.37358/RC.19.12.7777

Text
Dorel Dronca, Ioan Pet, Lavinia Stef, Gabi Dumitrescu, Silvia Patruica, Marioara Nicula, Liliana Petculescu-Ciochina, Mihaela Popa, Mirela Ahmadi,
Influence of Iron Administration on Kidney Serum Parameters,
Revista de Chimie,
Volume 70, Issue 12,
2019,
Pages 4466-4469,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.12.7777.
(https://revistadechimie.ro/Articles.asp?ID=7777)
Keywords: iron; creatinine; uric acid; blood urea nitrogen

RIS
TY - JOUR
T1 - Influence of Iron Administration on Kidney Serum Parameters
A1 - Dronca, Dorel
A2 - Pet, Ioan
A3 - Stef, Lavinia
A4 - Dumitrescu, Gabi
A5 - Patruica, Silvia
A6 - Nicula, Marioara
A7 - Petculescu-Ciochina, Liliana
A8 - Popa, Mihaela
A9 - Ahmadi, Mirela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 12
SP - 4466
EP - 4469
UR - https://doi.org/10.37358/RC.19.12.7777
KW - iron
KW - creatinine
KW - uric acid
KW - blood urea nitrogen
ER -

BibTex
@article{RevCh2019P4466,
author = {Dronca Dorel and Pet Ioan and Stef Lavinia and Dumitrescu Gabi and Patruica Silvia and Nicula Marioara and Petculescu-Ciochina Liliana and Popa Mihaela and Ahmadi Mirela},
title = {Influence of Iron Administration on Kidney Serum Parameters},
journal = {Revista de Chimie},
volume = {70},
number = {12},
pages = {4466-4469},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.12.7777},
url = {https://revistadechimie.ro/Articles.asp?ID=7777}
}

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