Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis

Tilinca, Mariana Cornelia; Nania, Csilla; Pal, Sandor; Tilinca, Raluca; Szabo, Monika; Nemes-Nagy, Eniko

Mariana Cornelia Tilinca, Csilla Nania, Sandor Pal, Raluca Tilinca, Monika Szabo, Eniko Nemes-Nagy

Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis

Abstract:

Ketoacidosis is a life-threatening complication of diabetes mellitus, especially type 1 diabetic patients being predisposed to this condition. Ketoacidosis might occur also in other types of diabetes triggered by circumstances leading to shortage of insulin. The aim of the study was the assessment of metabolic, hydroelectrolytic disturbances and the relationship between different parameters in patients hospitalized with diabetic ketoacidosis. We evaluated the clinical state, parameters of blood-gas analyzer, biochemistry and hematology laboratory results of 32 patients admitted with diabetic ketoacidosis between January-November 2018 at the Department of Diabetology, Nutrition and Metabolic Diseases of the Emergency County Hospital in Tîrgu Mureș. Demographic data, associated diseases, body mass index were also evaluated. The considered threshold of significance was 0.05. The distribution of type 1 and 2 diabetes was 40.6 and 46.9% in the studied group, 53.1% being male patients. Positive correlation could be observed between pH and base excess and between pH and bicarbonate values, while negative correlation could be found between triglyceridemia and body mass index (BMI). Severe hyperglycemia, very low pH values, glucosuria, ketonuria and electrolytic imbalances were very common in the studied patients. Pancreatitis, respiratory tract and urinary infections could be found in the background of ketoacidotic manifestations in the majority of the patients, dehydration occured in each of the cases. Many severe metabolic and hydroelectrolytic disturbances could be observed in the studied patients presenting diabetic ketoacidosis. Infectious diseases are the most common triggers of metabolic imbalance in diabetic patients.

Keywords:
diabetic ketoacidosis; blood-gas analyzer; metabolic parameters

Issue: 2020, Volume 71, Issue 1

Pages: 239-243

Publication date: 2020/2/7

https://doi.org/10.37358/RC.20.1.7839

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TILINCA, M.C., NANIA, C., PAL, S., TILINCA, R., SZABO, M., NEMES-NAGY, E., Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis, Rev. Chim., 71(1), 2020, 239-243.

Vancouver
Tilinca MC, Nania C, Pal S, Tilinca R, Szabo M, Nemes-Nagy E. Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis. Rev. Chim.[internet]. 2020 Jan;71(1):239-243. Available from: https://doi.org/10.37358/RC.20.1.7839

APA 6th edition
Tilinca, M.C., Nania, C., Pal, S., Tilinca, R., Szabo, M. & Nemes-Nagy, E. (2020). Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis. Revista de Chimie, 71(1), 239-243. https://doi.org/10.37358/RC.20.1.7839

Harvard
Tilinca, M.C., Nania, C., Pal, S., Tilinca, R., Szabo, M., Nemes-Nagy, E. (2020). 'Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis', Revista de Chimie, 71(1), pp. 239-243. https://doi.org/10.37358/RC.20.1.7839

IEEE
M.C. Tilinca, C. Nania, S. Pal, R. Tilinca, M. Szabo, E. Nemes-Nagy, "Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis". Revista de Chimie, vol. 71, no. 1, pp. 239-243, 2020. [online]. https://doi.org/10.37358/RC.20.1.7839

Text
Mariana Cornelia Tilinca, Csilla Nania, Sandor Pal, Raluca Tilinca, Monika Szabo, Eniko Nemes-Nagy,
Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis,
Revista de Chimie,
Volume 71, Issue 1,
2020,
Pages 239-243,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.1.7839.
(https://revistadechimie.ro/Articles.asp?ID=7839)
Keywords: diabetic ketoacidosis; blood-gas analyzer; metabolic parameters

RIS
TY - JOUR
T1 - Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis
A1 - Tilinca, Mariana Cornelia
A2 - Nania, Csilla
A3 - Pal, Sandor
A4 - Tilinca, Raluca
A5 - Szabo, Monika
A6 - Nemes-Nagy, Eniko
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 1
SP - 239
EP - 243
UR - https://doi.org/10.37358/RC.20.1.7839
KW - diabetic ketoacidosis
KW - blood-gas analyzer
KW - metabolic parameters
ER -

BibTex
@article{RevCh2020P239,
author = {Tilinca Mariana Cornelia and Nania Csilla and Pal Sandor and Tilinca Raluca and Szabo Monika and Nemes-Nagy Eniko},
title = {Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis},
journal = {Revista de Chimie},
volume = {71},
number = {1},
pages = {239-243},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.1.7839},
url = {https://revistadechimie.ro/Articles.asp?ID=7839}
}

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