Elena Mihalceanu, Ioana Sadyre Scripcariu, Ioan Tudor Lazar, Alexandra Pangal, Ana Maria Adam, Virgil Bulimar, Cristina Daniela Dimitriu, Irina Negru
Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia
Abstract:
Toxaemia is a pathological condition specific to the period of pregnancy which begins and is indissolubly related to the presence of placenta. Antiangiogenic factors, such as sFLT-1 (soluble tyrosine kinase receptor fms-like) and sEng (soluble endoglin) play an important role in the first part of pregnancy. They are linked to physiological vascular neoformation, and, in the second part of the pregnancy, grant the endothelial functionality and physiological vascular remodeling. The aim of the study is to try to establish the levels of the sFLT- 1/PIGF ratio, as a prognostic tool in the patient with pre-eclampsia, depending on the influence of the cumulative risk factors. The sFLT-1 / PIGF report is a potential prognostic parameter in monitoring preeclampsia. The results of our study confirm the importance of deterring these markers for the diagnosis and monitoring of hypertensive pregnancies and at the same time to emphasize that the sFLT-1/PIGF ratio is a good predictor of preeclampsia.
Cite this article as: MIHALCEANU, E., SCRIPCARIU, I.S., LAZAR, I.T., PANGAL, A., ADAM, A.M., BULIMAR, V., DIMITRIU, C.D., NEGRU, I., Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia, Rev. Chim., 71(1), 2020, 450-457.
Vancouver Mihalceanu E, Scripcariu IS, Lazar IT, Pangal A, Adam AM, Bulimar V, Dimitriu CD, Negru I. Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia. Rev. Chim.[internet]. 2020 Jan;71(1):450-457. Available from: https://doi.org/10.37358/RC.20.1.7874
APA 6th edition Mihalceanu, E., Scripcariu, I.S., Lazar, I.T., Pangal, A., Adam, A.M., Bulimar, V., Dimitriu, C.D. & Negru, I. (2020). Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia. Revista de Chimie, 71(1), 450-457. https://doi.org/10.37358/RC.20.1.7874
Harvard Mihalceanu, E., Scripcariu, I.S., Lazar, I.T., Pangal, A., Adam, A.M., Bulimar, V., Dimitriu, C.D., Negru, I. (2020). 'Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia', Revista de Chimie, 71(1), pp. 450-457. https://doi.org/10.37358/RC.20.1.7874
IEEE E. Mihalceanu, I.S. Scripcariu, I.T. Lazar, A. Pangal, A.M. Adam, V. Bulimar, C.D. Dimitriu, I. Negru, "Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia". Revista de Chimie, vol. 71, no. 1, pp. 450-457, 2020. [online]. https://doi.org/10.37358/RC.20.1.7874
Text Elena Mihalceanu, Ioana Sadyre Scripcariu, Ioan Tudor Lazar, Alexandra Pangal, Ana Maria Adam, Virgil Bulimar, Cristina Daniela Dimitriu, Irina Negru, Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia, Revista de Chimie, Volume 71, Issue 1, 2020, Pages 450-457, ISSN 2668-8212, https://doi.org/10.37358/RC.20.1.7874. (https://revistadechimie.ro/Articles.asp?ID=7874) Keywords: pregnancy; antiangiogenic factors; toxaemia
RIS TY - JOUR T1 - Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia A1 - Mihalceanu, Elena A2 - Scripcariu, Ioana Sadyre A3 - Lazar, Ioan Tudor A4 - Pangal, Alexandra A5 - Adam, Ana Maria A6 - Bulimar, Virgil A7 - Dimitriu, Cristina Daniela A8 - Negru, Irina JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2020 VL - 71 IS - 1 SP - 450 EP - 457 UR - https://doi.org/10.37358/RC.20.1.7874 KW - pregnancy KW - antiangiogenic factors KW - toxaemia ER -
BibTex @article{RevCh2020P450, author = {Mihalceanu Elena and Scripcariu Ioana Sadyre and Lazar Ioan Tudor and Pangal Alexandra and Adam Ana Maria and Bulimar Virgil and Dimitriu Cristina Daniela and Negru Irina}, title = {Expression of PIGF and sFLT-1 Biomarkers in Pregnancy Toxaemia}, journal = {Revista de Chimie}, volume = {71}, number = {1}, pages = {450-457}, year = {2020}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.20.1.7874}, url = {https://revistadechimie.ro/Articles.asp?ID=7874} }
