Electrochemical Detection of the Exhaled Nitric Oxide in Children

Diaconu, Radu; Dumitrescu, Florentina; Stoica, Loredana; Ciobanu, Ovidiu Mircea; Udristoiu, Ion; Stan, Iustina Violeta; Berbece, Sorin; Selaru, Loredana

Radu Diaconu, Florentina Dumitrescu, Loredana Stoica, Ovidiu Mircea Ciobanu, Ion Udristoiu, Iustina Violeta Stan, Sorin Berbece, Loredana Selaru

Electrochemical Detection of the Exhaled Nitric Oxide in Children

Abstract:

Dosage of gaseous inflammatory markers is a promising method of evaluating various types of pediatric pathologies and not only. The fraction of exhaled nitric oxide (FeNO) can be quantified by electrochemical detection using a portable analyzer that delivers fast, reproducible, and widely available results. The objectives of our study were to evaluate the accessibility of the pediatric dosing method and the utility of FeNO for the diagnosis of atopic pathology in hospitalized children. We conducted a retrospective study that included children aged over 6 years admitted to the Pediatric Department of the Municipal Hospital Filantropia in Craiova who were evaluated according to the type of training performed for the determination of FeNO and according to the diagnosis of admission. Results. Using a human model was more effective in obtaining a valid result compared to the use of the demo provided by the manufacturer, especially at younger age (p = 0.05 and respectively, 0.04 - Student t test). Among the various allergic pathologies studied, children with asthma were the ones who recorded the highest levels of nitric oxide, even when compared to the rest of atopic children (p = 0.01 - t test). Moreover, the proportion of cases with positive values was increased in asthmatic children compared to the rest of the type of allergic pathology, but these values were at the limit of statistical significance (p = 0.08 - chi square and Mid-P exact test). The conclusion of our study was that it is possible to improve compliance with FeNO assessment especially at younger age, and the utility of the method is still limited, especially in asthma cases.

Keywords:
electrochemical; children; nitric oxide; atopy

Issue: 2020, Volume 71, Issue 2

Pages: 105-109

Publication date: 2020/3/3

https://doi.org/10.37358/RC.20.2.7900

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
DIACONU, R., DUMITRESCU, F., STOICA, L., CIOBANU, O.M., UDRISTOIU, I., STAN, I.V., BERBECE, S., SELARU, L., Electrochemical Detection of the Exhaled Nitric Oxide in Children, Rev. Chim., 71(2), 2020, 105-109.

Vancouver
Diaconu R, Dumitrescu F, Stoica L, Ciobanu OM, Udristoiu I, Stan IV, Berbece S, Selaru L. Electrochemical Detection of the Exhaled Nitric Oxide in Children. Rev. Chim.[internet]. 2020 Feb;71(2):105-109. Available from: https://doi.org/10.37358/RC.20.2.7900

APA 6th edition
Diaconu, R., Dumitrescu, F., Stoica, L., Ciobanu, O.M., Udristoiu, I., Stan, I.V., Berbece, S. & Selaru, L. (2020). Electrochemical Detection of the Exhaled Nitric Oxide in Children. Revista de Chimie, 71(2), 105-109. https://doi.org/10.37358/RC.20.2.7900

Harvard
Diaconu, R., Dumitrescu, F., Stoica, L., Ciobanu, O.M., Udristoiu, I., Stan, I.V., Berbece, S., Selaru, L. (2020). 'Electrochemical Detection of the Exhaled Nitric Oxide in Children', Revista de Chimie, 71(2), pp. 105-109. https://doi.org/10.37358/RC.20.2.7900

IEEE
R. Diaconu, F. Dumitrescu, L. Stoica, O.M. Ciobanu, I. Udristoiu, I.V. Stan, S. Berbece, L. Selaru, "Electrochemical Detection of the Exhaled Nitric Oxide in Children". Revista de Chimie, vol. 71, no. 2, pp. 105-109, 2020. [online]. https://doi.org/10.37358/RC.20.2.7900

Text
Radu Diaconu, Florentina Dumitrescu, Loredana Stoica, Ovidiu Mircea Ciobanu, Ion Udristoiu, Iustina Violeta Stan, Sorin Berbece, Loredana Selaru,
Electrochemical Detection of the Exhaled Nitric Oxide in Children,
Revista de Chimie,
Volume 71, Issue 2,
2020,
Pages 105-109,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.2.7900.
(https://revistadechimie.ro/Articles.asp?ID=7900)
Keywords: electrochemical; children; nitric oxide; atopy

RIS
TY - JOUR
T1 - Electrochemical Detection of the Exhaled Nitric Oxide in Children
A1 - Diaconu, Radu
A2 - Dumitrescu, Florentina
A3 - Stoica, Loredana
A4 - Ciobanu, Ovidiu Mircea
A5 - Udristoiu, Ion
A6 - Stan, Iustina Violeta
A7 - Berbece, Sorin
A8 - Selaru, Loredana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 2
SP - 105
EP - 109
UR - https://doi.org/10.37358/RC.20.2.7900
KW - electrochemical
KW - children
KW - nitric oxide
KW - atopy
ER -

BibTex
@article{RevCh2020P105,
author = {Diaconu Radu and Dumitrescu Florentina and Stoica Loredana and Ciobanu Ovidiu Mircea and Udristoiu Ion and Stan Iustina Violeta and Berbece Sorin and Selaru Loredana},
title = {Electrochemical Detection of the Exhaled Nitric Oxide in Children},
journal = {Revista de Chimie},
volume = {71},
number = {2},
pages = {105-109},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.2.7900},
url = {https://revistadechimie.ro/Articles.asp?ID=7900}
}

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